DK1399023T3 - Sammensætninger til systemisk indgivelse af sekvenser, der koder for knoglemorfogenese-proteiner - Google Patents

Sammensætninger til systemisk indgivelse af sekvenser, der koder for knoglemorfogenese-proteiner

Info

Publication number
DK1399023T3
DK1399023T3 DK02734594T DK02734594T DK1399023T3 DK 1399023 T3 DK1399023 T3 DK 1399023T3 DK 02734594 T DK02734594 T DK 02734594T DK 02734594 T DK02734594 T DK 02734594T DK 1399023 T3 DK1399023 T3 DK 1399023T3
Authority
DK
Denmark
Prior art keywords
compositions
systemic administration
methods
sequences encoding
bone morphogenesis
Prior art date
Application number
DK02734594T
Other languages
Danish (da)
English (en)
Inventor
Brian Clancy
Debra D Pittman
Howard Seeherman
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1399023T3 publication Critical patent/DK1399023T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
DK02734594T 2001-06-01 2002-05-31 Sammensætninger til systemisk indgivelse af sekvenser, der koder for knoglemorfogenese-proteiner DK1399023T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29515301P 2001-06-01 2001-06-01
PCT/US2002/017011 WO2002099037A2 (fr) 2001-06-01 2002-05-31 Compositions et methodes pour l'administration systemique de sequences codant pour des proteines morphogenetiques osseuses

Publications (1)

Publication Number Publication Date
DK1399023T3 true DK1399023T3 (da) 2008-08-18

Family

ID=23136452

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02734594T DK1399023T3 (da) 2001-06-01 2002-05-31 Sammensætninger til systemisk indgivelse af sekvenser, der koder for knoglemorfogenese-proteiner

Country Status (11)

Country Link
US (2) US7226587B2 (fr)
EP (1) EP1399023B1 (fr)
JP (1) JP2005500280A (fr)
AT (1) ATE393573T1 (fr)
CA (1) CA2449008A1 (fr)
DE (1) DE60226321T2 (fr)
DK (1) DK1399023T3 (fr)
ES (1) ES2305246T3 (fr)
HK (1) HK1063201A1 (fr)
NZ (1) NZ530045A (fr)
WO (1) WO2002099037A2 (fr)

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AU2006230434A1 (en) * 2005-03-30 2006-10-05 Wyeth Methods for stimulating hair growth by administering BMPs
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US20070105769A1 (en) * 2005-11-07 2007-05-10 Ebi, L.P. Methods of treating tissue defects
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
EP2186823A1 (fr) 2005-11-14 2010-05-19 Merial Limited Thérapie génique pour traiter l'insuffisance rénale
EP1998796A2 (fr) * 2006-03-28 2008-12-10 Wyeth a Corporation of the State of Delaware Modulateurs de gdf-9/bmp-15 pour le traitement de troubles des os
US8034014B2 (en) 2007-03-06 2011-10-11 Biomet Biologics, Llc Angiogenesis initation and growth
DK2331057T3 (da) * 2008-09-10 2019-06-17 Univ Bradford Sammensætninger og fremgangsmåder til modulering af hudpigmentering
US10136891B2 (en) * 2015-03-25 2018-11-27 Ethicon Llc Naturally derived bioabsorbable polymer gel adhesive for releasably attaching a staple buttress to a surgical stapler
AU2016333996B2 (en) 2015-10-05 2020-05-28 Salk Institute For Biological Studies Synthetic adenoviruses with tropism to damaged tissue for use in promoting wound repair and tissue regeneration

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IT1302534B1 (it) * 1998-12-21 2000-09-05 Fidia Advanced Biopolymers Srl Composizioni iniettabili, biocompatibili e biodegradabili comprendentialmeno un derivato dell'acido ialuronico, cellule condrogeniche, per
US6603362B2 (en) * 2000-03-14 2003-08-05 Intersil Americas Inc. Subsampling digitizer-based frequency synthesizer
WO2002099037A2 (fr) * 2001-06-01 2002-12-12 Wyeth Compositions et methodes pour l'administration systemique de sequences codant pour des proteines morphogenetiques osseuses

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JP2005500280A (ja) 2005-01-06
EP1399023B1 (fr) 2008-04-30
DE60226321D1 (de) 2008-06-12
EP1399023A2 (fr) 2004-03-24
WO2002099037A2 (fr) 2002-12-12
US20030170208A1 (en) 2003-09-11
US20060099186A1 (en) 2006-05-11
ES2305246T3 (es) 2008-11-01
WO2002099037A3 (fr) 2003-02-27
CA2449008A1 (fr) 2002-12-12
ATE393573T1 (de) 2008-05-15
DE60226321T2 (de) 2009-07-09
NZ530045A (en) 2007-07-27
EP1399023A4 (fr) 2006-02-01
US7226587B2 (en) 2007-06-05
HK1063201A1 (en) 2004-12-17

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