DK1381614T3 - Antidepressive azaheterocyclylmethylderivater af 2,3-dihydro-1,4-dioxino[2,3-f]quinoxalin - Google Patents

Antidepressive azaheterocyclylmethylderivater af 2,3-dihydro-1,4-dioxino[2,3-f]quinoxalin

Info

Publication number
DK1381614T3
DK1381614T3 DK02725787T DK02725787T DK1381614T3 DK 1381614 T3 DK1381614 T3 DK 1381614T3 DK 02725787 T DK02725787 T DK 02725787T DK 02725787 T DK02725787 T DK 02725787T DK 1381614 T3 DK1381614 T3 DK 1381614T3
Authority
DK
Denmark
Prior art keywords
azaheterocyclyl
dioxino
antidepressant
quinoxaline
dihydro
Prior art date
Application number
DK02725787T
Other languages
Danish (da)
English (en)
Inventor
Jonathan Laird Gross
Gary Paul Stack
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of DK1381614T3 publication Critical patent/DK1381614T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK02725787T 2001-04-26 2002-04-23 Antidepressive azaheterocyclylmethylderivater af 2,3-dihydro-1,4-dioxino[2,3-f]quinoxalin DK1381614T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28643801P 2001-04-26 2001-04-26

Publications (1)

Publication Number Publication Date
DK1381614T3 true DK1381614T3 (da) 2006-11-06

Family

ID=23098606

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02725787T DK1381614T3 (da) 2001-04-26 2002-04-23 Antidepressive azaheterocyclylmethylderivater af 2,3-dihydro-1,4-dioxino[2,3-f]quinoxalin

Country Status (13)

Country Link
US (1) US6617327B2 (pt)
EP (1) EP1381614B1 (pt)
JP (1) JP2004527563A (pt)
CN (1) CN1250553C (pt)
AT (1) ATE334989T1 (pt)
AU (1) AU2002256334A1 (pt)
BR (1) BR0209342A (pt)
CA (1) CA2445581A1 (pt)
DE (1) DE60213576T2 (pt)
DK (1) DK1381614T3 (pt)
ES (1) ES2269678T3 (pt)
MX (1) MXPA03009826A (pt)
WO (1) WO2002088144A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040192730A1 (en) * 2003-03-13 2004-09-30 Dynogen Pharmaceuticals, Inc. Methods of using compounds with combined 5-HT1A and SSRI activities as-needed to treat sexual dysfunction
EP2332940B1 (en) 2004-03-30 2012-10-31 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of JAK and other protein kinases
WO2006089053A2 (en) * 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
JP5406039B2 (ja) 2006-12-21 2014-02-05 バーテックス ファーマシューティカルズ インコーポレイテッド タンパク質キナーゼ阻害剤として有用な５−シアノ−４−（ピロロ［２，３ｂ］ピリジン−３−イル）−ピリミジン誘導体
ES2604667T3 (es) 2009-06-17 2017-03-08 Vertex Pharmaceuticals Incorporated Inhibidores de la replicación de virus de influenza
CA2822057A1 (en) 2010-12-16 2012-06-21 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
MX2016006200A (es) 2013-11-13 2016-08-08 Vertex Pharma Metodos para preparar inhibidores de la replicacion de virus de influenza.
EP3068776B1 (en) 2013-11-13 2019-05-29 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
EP3294735B8 (en) 2015-05-13 2022-01-05 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
EP3294717B1 (en) 2015-05-13 2020-07-29 Vertex Pharmaceuticals Inc. Methods of preparing inhibitors of influenza viruses replication

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991013872A1 (en) 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
US5756532A (en) 1995-11-06 1998-05-26 American Home Products Corporation Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9526495D0 (en) * 1995-12-23 1996-02-28 Knoll Ag Therapeutic agents
US5869490A (en) 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one

Also Published As

Publication number Publication date
DE60213576T2 (de) 2007-10-18
WO2002088144A3 (en) 2002-12-19
EP1381614B1 (en) 2006-08-02
MXPA03009826A (es) 2005-03-07
US20020183329A1 (en) 2002-12-05
CA2445581A1 (en) 2002-11-07
BR0209342A (pt) 2004-06-15
EP1381614A2 (en) 2004-01-21
US6617327B2 (en) 2003-09-09
JP2004527563A (ja) 2004-09-09
CN1250553C (zh) 2006-04-12
CN1503801A (zh) 2004-06-09
WO2002088144A2 (en) 2002-11-07
ES2269678T3 (es) 2007-04-01
DE60213576D1 (de) 2006-09-14
AU2002256334A1 (en) 2002-11-11
ATE334989T1 (de) 2006-08-15

Similar Documents

Publication Publication Date Title
WO2002085896A8 (en) Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan
MXPA06001647A (es) 6-(2, 2, 2-trifluoroetilamino) -7-cloro-2, 3, 4, 5-tetrahidro- 1h-benzo[d] azepina como un agonista del receptor 5-ht2c.
UA85699C2 (en) 6-substituted 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
EA200601269A1 (ru) Лекарственное средство, содержащее производные фенилпиперазина
HK1068622A1 (en) Novel heteroaryl derivatives, their preparation and use
DK1381614T3 (da) Antidepressive azaheterocyclylmethylderivater af 2,3-dihydro-1,4-dioxino[2,3-f]quinoxalin
WO2005099702A3 (en) R(-)-11-hydroxyaporphine derivatives and uses thereof
DK1381613T3 (da) Antidepressive azaheterocyclylmethylderivater af oxaheterocyclokondenserede 1,4-benzodioxaner
ATE277934T1 (de) Antidepressive azaheterocyclylmethylderivate von 7,8-dihydro-1,6,9-trioxa-3- azacyclopenta(a)naphthalin
DE60201592D1 (de) ANTIDEPRESSIVE INDOLTETRAHYDROPYRIDIN-DERIVATE VON 2,3-DIHYDRO-7H[1,4]DIOXINO[2,3-e]INDOL
ATE304016T1 (de) Antidepressive (sssri) azaheterocyclylmethylderivate von 7,8-dihydro-3h- 6,9-dioxa-1,3-diazacyclopenta (a) naphthalin
DK1532131T3 (da) Motilid-forbindelser
DK1392697T3 (da) Antidepressive azaheterocyclylmethylderivater af 2,3-dihydro-1,4-dioxino[2.3-f]quinolin
MXPA05010678A (es) Derivados de 4-(2-fenilsulfanil-fenil)-1,2,3,6-tetrahidropiridina como inhibidores de recaptacion de serotonina.
CA2451229A1 (en) Indole derivatives
EA200500865A1 (ru) Синергетическая комбинация, включающая рофлумиласт и r,r-формотерол