DK1370571T3 - Fremgangsmåde og apparat til gelfri kvalitativ og kvantitativ proteomanalyse samt anvendelser deraf - Google Patents

Fremgangsmåde og apparat til gelfri kvalitativ og kvantitativ proteomanalyse samt anvendelser deraf

Info

Publication number
DK1370571T3
DK1370571T3 DK02735176T DK02735176T DK1370571T3 DK 1370571 T3 DK1370571 T3 DK 1370571T3 DK 02735176 T DK02735176 T DK 02735176T DK 02735176 T DK02735176 T DK 02735176T DK 1370571 T3 DK1370571 T3 DK 1370571T3
Authority
DK
Denmark
Prior art keywords
peptides
gel
applications
qualitative
proteomic analysis
Prior art date
Application number
DK02735176T
Other languages
Danish (da)
English (en)
Inventor
Joel Vandekerckhove
Kris Gevaert
Original Assignee
Vlaams Interuniv Inst Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vlaams Interuniv Inst Biotech filed Critical Vlaams Interuniv Inst Biotech
Application granted granted Critical
Publication of DK1370571T3 publication Critical patent/DK1370571T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8411—Intermediate storage of effluent, including condensation on surface
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G01N30/467—Flow patterns using more than one column with separation columns in parallel all columns being identical
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/80—Fraction collectors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK02735176T 2001-03-22 2002-03-22 Fremgangsmåde og apparat til gelfri kvalitativ og kvantitativ proteomanalyse samt anvendelser deraf DK1370571T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27817101P 2001-03-22 2001-03-22
US31874901P 2001-09-12 2001-09-12
US32399901P 2001-09-20 2001-09-20
PCT/EP2002/003368 WO2002077016A2 (en) 2001-03-22 2002-03-22 Methods and apparatus for gel-free qualitative and quantitative proteome analysis, and uses therefore

Publications (1)

Publication Number Publication Date
DK1370571T3 true DK1370571T3 (da) 2005-10-17

Family

ID=27402974

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02735176T DK1370571T3 (da) 2001-03-22 2002-03-22 Fremgangsmåde og apparat til gelfri kvalitativ og kvantitativ proteomanalyse samt anvendelser deraf

Country Status (11)

Country Link
US (2) US6908740B2 (de)
EP (1) EP1370571B1 (de)
JP (1) JP4300029B2 (de)
AT (1) ATE297944T1 (de)
AU (2) AU2002310985B2 (de)
CA (2) CA2504413A1 (de)
DE (1) DE60204669T2 (de)
DK (1) DK1370571T3 (de)
ES (1) ES2242864T3 (de)
PT (1) PT1370571E (de)
WO (1) WO2002077016A2 (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078375B1 (en) * 1996-10-25 2006-07-18 Peter Mose Larsen Diabetes-mediating proteins and therapeutic uses thereof
PT1370571E (pt) * 2001-03-22 2005-09-30 Vlaams Interuniv Inst Biotech Processos e aparelhos para analises qualitativas e quantitativas, isentas de gel, do proteoma e as suas utilizacoes
CA2349265A1 (en) * 2001-05-30 2002-11-30 Andrew Emili Protein expression profile database
CA2393726A1 (en) * 2002-07-16 2004-01-16 Steven J. Locke Quantitative proteomics via isotopically differentiated derivatization
US7846748B2 (en) 2002-12-02 2010-12-07 The University Of North Carolina At Chapel Hill Methods of quantitation and identification of peptides and proteins
US7041472B2 (en) * 2002-12-25 2006-05-09 Shimadzu Corporation Method for selectively collecting N-terminal peptide fragment of protein
US7422865B2 (en) 2003-01-13 2008-09-09 Agilent Technologies, Inc. Method of identifying peptides in a proteomic sample
CA2529863A1 (en) * 2003-06-17 2004-12-23 Vib Vzw Peptide combos and their uses
DE10340521B4 (de) * 2003-09-03 2012-01-05 Bruker Daltonik Gmbh Verfahren selektiver Kapillarelektrophorese
JP4576972B2 (ja) * 2003-10-16 2010-11-10 株式会社島津製作所 タンパク質又はペプチドのスルホン酸誘導体化されたｎ末端ペプチドフラグメントを質量分析する方法
US20050153309A1 (en) 2003-12-22 2005-07-14 David Hoon Method and apparatus for in vivo surveillance of circulating biological components
US7553625B2 (en) * 2003-12-22 2009-06-30 John Wayne Cancer Institute Method and apparatus for in vivo collection of circulating biological components
WO2005079360A2 (en) * 2004-02-12 2005-09-01 Ionwerks, Inc. Advanced optics for rapidly patterned lasser profiles in analytical spectrometry
ATE421733T1 (de) * 2004-03-16 2009-02-15 Centre Nat Rech Scient Methode zur identifizierung von unbekannten proteinen mittels zwei-dimensionaler auftrennung und verwendung von markern
GB0414233D0 (en) * 2004-06-25 2004-07-28 Bioinvent Int Ab Analysis method
US7024800B2 (en) 2004-07-19 2006-04-11 Earthrenew, Inc. Process and system for drying and heat treating materials
US20070084077A1 (en) * 2004-07-19 2007-04-19 Gorbell Brian N Control system for gas turbine in material treatment unit
US7685737B2 (en) 2004-07-19 2010-03-30 Earthrenew, Inc. Process and system for drying and heat treating materials
US7024796B2 (en) * 2004-07-19 2006-04-11 Earthrenew, Inc. Process and apparatus for manufacture of fertilizer products from manure and sewage
JP5188804B2 (ja) * 2004-08-03 2013-04-24 トランステック ファーマ，インコーポレイティド Ｒａｇｅ融合タンパク質及びその使用方法
WO2006037059A2 (en) * 2004-09-27 2006-04-06 The Johns Hopkins Universtiy Point-of-care mass spectrometer system
JP4563764B2 (ja) * 2004-10-01 2010-10-13 丸善製薬株式会社 ペプチドの定量方法
WO2006055615A2 (en) 2004-11-15 2006-05-26 University Of North Dakota A method for single oxygen atom incorporation into digested peptides using peptidases
US7417223B2 (en) * 2005-10-28 2008-08-26 Mds Inc. Method, system and computer software product for specific identification of reaction pairs associated by specific neutral differences
US7610692B2 (en) 2006-01-18 2009-11-03 Earthrenew, Inc. Systems for prevention of HAP emissions and for efficient drying/dehydration processes
US20070163316A1 (en) * 2006-01-18 2007-07-19 Earthrenew Organics Ltd. High organic matter products and related systems for restoring organic matter and nutrients in soil
US20080319678A1 (en) * 2006-02-15 2008-12-25 University Of Virginia Patent Foundation Mass Tagging for Quantitative Analysis of Biomolecules using 13C Labeled Phenylisocyanate
DE602007009954D1 (de) 2006-03-22 2010-12-02 Viral Logic Systems Technology Verfahren zur identifizierung von polypeptid-targets
JP4609370B2 (ja) * 2006-04-24 2011-01-12 株式会社島津製作所 硫黄含有ペプチドの処理法及び硫黄原子含有ペプチドの解析法
US8580534B2 (en) * 2006-06-30 2013-11-12 The University Of North Dakota Method for incorporation of two oxygen atoms into digested peptides using peptidases
WO2008073146A2 (en) * 2006-07-06 2008-06-19 University Of Wyoming Method and apparatus for pyrolysis-induced cleavage in peptides and proteins
US8637325B2 (en) * 2009-02-16 2014-01-28 University Of Wyoming Method and apparatus for pyrolysis-induced cleavage in peptides and proteins
WO2008138916A1 (en) * 2007-05-10 2008-11-20 Pronota N.V. Isolation of peptides and proteomics platform
WO2009003952A2 (en) * 2007-06-29 2009-01-08 Pronota N.V. Column and method for preparing a biological sample for protein profiling
WO2009050261A1 (en) * 2007-10-19 2009-04-23 Pronota N.V. Preparation of samples for proteome analysis
EP2062911A1 (de) * 2007-11-26 2009-05-27 Koninklijke Philips Electronics N.V. Selektive Anreicherung von posttranslational-modifizierten Proteinen
JP4998230B2 (ja) * 2007-11-26 2012-08-15 株式会社島津製作所 タンパク質試料中のメチオニン残基の酸化状態を解析する方法
EP2062910A1 (de) * 2007-11-26 2009-05-27 Koninklijke Philips Electronics N.V. Selektive Anreicherung von posttranslational modifizierten Proteinen und/oder Peptiden aus komplexen Proben
CN103713073B (zh) 2007-12-05 2016-10-05 全技术联合公司 用于分析样本和收集样本流份的方法和装置
EP2108654A1 (de) * 2008-04-07 2009-10-14 Koninklijke Philips Electronics N.V. Selektive Anreicherung von N-terminal modifizierten Peptiden aus komplexen Proben
JP5181908B2 (ja) * 2008-08-04 2013-04-10 株式会社島津製作所 質量分析データ解析装置
EP2373422A4 (de) 2008-12-04 2017-01-18 Büchi Labortechnik AG Verfahren und vorrichtung zur übertragung aliquoter proben einer flüssigkeit
CN102316950A (zh) 2008-12-10 2012-01-11 全技术联合公司 色谱系统和系统部件
WO2010086382A1 (en) 2009-01-30 2010-08-05 Pronota N.V. Target for treatment of acute heart failure
WO2010086384A1 (en) 2009-01-30 2010-08-05 Pronota N.V. Target for treatment of acute heart failure
CA2746128C (en) 2009-01-30 2020-07-28 Pronota N.V. Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
US8314934B2 (en) 2009-09-01 2012-11-20 Alltech Associates, Inc. Methods and apparatus for analyzing samples and collecting sample fractions
WO2011128357A2 (en) 2010-04-13 2011-10-20 Pronota N.V. Biomarkers for hypertensive disorders of pregnancy
FR2982367B1 (fr) * 2011-11-08 2013-12-27 Biomerieux Sa Procede de detection de l'hemolysine delta de staphylococcus aureus par spectrometrie de masse directement a partir d'une population bacterienne
US9145764B2 (en) 2011-11-22 2015-09-29 International Strategic Alliance, Lc Pass-through bulkhead connection switch for a perforating gun
EP2956768B1 (de) 2013-02-13 2023-10-18 Promega Corporation Verfahren zur bewertung der leistung eines instruments mit funktionalitäten der flüssigkeitschromatographie und der massenspektrometrie
US20170370813A1 (en) * 2015-01-09 2017-12-28 Children's Medical Center Corporation Methods of membrane-based proteomic sample preparation
US20170168055A1 (en) * 2015-12-11 2017-06-15 Expression Pathology, Inc. SRM/MRM Assays
US10775384B2 (en) 2016-02-02 2020-09-15 Sandoz Ag Sensitive detection of protein heterogeneity by use of enzyme cascades
CN109561890A (zh) 2016-06-09 2019-04-02 海马切克公司 用于检测和可逆地捕获活体内体液中的细胞的收集器
US10429364B2 (en) * 2017-01-31 2019-10-01 Thermo Finnigan Llc Detecting low level LCMS components by chromatographic reconstruction
GB201701986D0 (en) 2017-02-07 2017-03-22 Thermo Fisher Scient (Bremen) Gmbh n
WO2020021496A1 (en) * 2018-07-27 2020-01-30 Waters Technologies Corporation Liquid chromatography/mass spectrometry methods for the analysis of polar molecules
EP3910329A1 (de) * 2020-05-14 2021-11-17 LG Chem, Ltd. Online-system zur verbesserung der nachweisempfindlichkeit von analyten durch flüssigkeitschromatographie und analyseverfahren damit
JP2023011436A (ja) * 2021-07-12 2023-01-24 株式会社日立ハイテク 質量分析システム、処理装置及び異常検出方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE253126T1 (de) * 1998-08-25 2003-11-15 Univ Washington Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
EP1006362A1 (de) * 1998-12-02 2000-06-07 Michael Dr. Cahill Methode und Apparat für die Abtrennung von Komponenten aus einem biologischen Material
US6818454B2 (en) * 2001-02-16 2004-11-16 Battelle Memorial Institute Phosphoprotein binding agents and methods of their use
PT1370571E (pt) * 2001-03-22 2005-09-30 Vlaams Interuniv Inst Biotech Processos e aparelhos para analises qualitativas e quantitativas, isentas de gel, do proteoma e as suas utilizacoes

Also Published As

Publication number Publication date
AU2006201455B2 (en) 2008-10-09
CA2419492A1 (en) 2002-10-03
WO2002077016A2 (en) 2002-10-03
WO2002077016A3 (en) 2003-10-09
DE60204669T2 (de) 2006-05-04
US6908740B2 (en) 2005-06-21
US20050196823A1 (en) 2005-09-08
AU2002310985B2 (en) 2006-05-11
DE60204669D1 (de) 2005-07-21
CA2419492C (en) 2005-07-05
JP2005500990A (ja) 2005-01-13
ES2242864T3 (es) 2005-11-16
EP1370571B1 (de) 2005-06-15
CA2504413A1 (en) 2002-10-03
PT1370571E (pt) 2005-09-30
ATE297944T1 (de) 2005-07-15
US20040005633A1 (en) 2004-01-08
EP1370571A2 (de) 2003-12-17
AU2006201455A1 (en) 2006-04-27
JP4300029B2 (ja) 2009-07-22

Similar Documents

Publication Publication Date Title
DK1370571T3 (da) Fremgangsmåde og apparat til gelfri kvalitativ og kvantitativ proteomanalyse samt anvendelser deraf
GB2430794A (en) Method and apparatus for identifying proteins in mixtures
DK1502102T3 (da) Forbindelser og fremgangsmåder til analysering af proteomet
IS7611A (is) Örfylki og aðferð til þess að framkvæma blöndunarhvörf fyrir fjölda sýna á einu örfylki
ATE327511T1 (de) Proteom-analyseverfahren
WO2001084140A3 (de) Verfahren und vorrichtung zur qualitativen und/oder quantitativen bestimmung eines protein- und/oder peptidmusters einer flüssigkeitsprobe, die dem menschlichen oder tierischen körper entnommen wird
GB2423819A (en) Apparatus and method for analysis of molecules
HUP0200400A2 (hu) Fehérjék izolálása és elemzése
WO2004040257A3 (en) Nox monitor using differential mobility spectrometry
CA2405501A1 (en) A method and device for analysis of charged molecules by solution isoelectric focusing
WO2004064972A3 (en) Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
WO2002090929A3 (en) Process for analyzing protein samples
IL154188A0 (en) Method and system for identifying and quantifying chemical components of a mixture
DE69905265T2 (de) Charakterisierung von polypeptiden durch spaltung und massenspektrometrie
ATE268903T1 (de) Verfahren und vorrichtung zur identifikation oder karakterisierung von polypeptiden
ATE506616T1 (de) Screening-verfahren
WO2002086081A3 (en) Methods and systems for identifying proteins
Righetti et al. The proteome: anno Domini 2002
AU2002361075A1 (en) Test result analysis apparatus, method, and program, and learning support system and method
AU2174002A (en) Method for analyzing proteins
WO2003025213A3 (en) Yeast proteome analysis
ATE443711T1 (de) Verfahren zur erkennung, analyse und isolation von entstehenden proteinen
NO20015470L (no) Anordning for sammenkobling av, samt analysesystem omfattende et apparat for kapill¶r elektroforese og et apparat for massespektrometri
DE69927691D1 (de) Verfahren zur eiweissanalyse
WO2002072863A3 (en) Methods for large scale protein matching