DK1370243T3 - Fremgangsmåde til at opnå mikropartikler, der indeholder en H+,K+-ATPase-inhibitor - Google Patents
Fremgangsmåde til at opnå mikropartikler, der indeholder en H+,K+-ATPase-inhibitorInfo
- Publication number
- DK1370243T3 DK1370243T3 DK02701872T DK02701872T DK1370243T3 DK 1370243 T3 DK1370243 T3 DK 1370243T3 DK 02701872 T DK02701872 T DK 02701872T DK 02701872 T DK02701872 T DK 02701872T DK 1370243 T3 DK1370243 T3 DK 1370243T3
- Authority
- DK
- Denmark
- Prior art keywords
- sup
- microparticles containing
- atpase inhibitor
- obtaining microparticles
- atp
- Prior art date
Links
- 239000011859 microparticle Substances 0.000 title abstract 4
- 229940121819 ATPase inhibitor Drugs 0.000 title abstract 3
- 239000000362 adenosine triphosphatase inhibitor Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000002253 acid Substances 0.000 abstract 1
- 238000009477 fluid bed granulation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Disintegrating Or Milling (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0100822A SE0100822D0 (sv) | 2001-03-09 | 2001-03-09 | Method II to obtain microparticles |
| PCT/SE2002/000400 WO2002072071A1 (en) | 2001-03-09 | 2002-03-06 | Method to obtain microparticles containing a h+, k+ -atp-ase inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1370243T3 true DK1370243T3 (da) | 2008-10-13 |
Family
ID=20283293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02701872T DK1370243T3 (da) | 2001-03-09 | 2002-03-06 | Fremgangsmåde til at opnå mikropartikler, der indeholder en H+,K+-ATPase-inhibitor |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20040101565A1 (OSRAM) |
| EP (1) | EP1370243B1 (OSRAM) |
| JP (1) | JP2004522796A (OSRAM) |
| KR (1) | KR20030081506A (OSRAM) |
| CN (1) | CN1507343A (OSRAM) |
| AT (1) | ATE400253T1 (OSRAM) |
| AU (1) | AU2002235101B8 (OSRAM) |
| BR (1) | BR0207827A (OSRAM) |
| CA (1) | CA2440163A1 (OSRAM) |
| DE (1) | DE60227488D1 (OSRAM) |
| DK (1) | DK1370243T3 (OSRAM) |
| ES (1) | ES2307722T3 (OSRAM) |
| IL (1) | IL157467A0 (OSRAM) |
| MX (1) | MXPA03007887A (OSRAM) |
| NO (1) | NO20033966L (OSRAM) |
| NZ (1) | NZ527997A (OSRAM) |
| PT (1) | PT1370243E (OSRAM) |
| SE (1) | SE0100822D0 (OSRAM) |
| SI (1) | SI1370243T1 (OSRAM) |
| WO (1) | WO2002072071A1 (OSRAM) |
| ZA (1) | ZA200306614B (OSRAM) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060159756A1 (en) * | 1999-09-10 | 2006-07-20 | Brita Sjoblom | Method to obtain microparticles containing an H+,K+-ATP-ASE inhibitor |
| SE0100823D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method I to obtain microparticles |
| US6607784B2 (en) | 2000-12-22 | 2003-08-19 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US7193084B2 (en) | 2000-12-22 | 2007-03-20 | Baxter International Inc. | Polymorphic form of itraconazole |
| US6977085B2 (en) | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
| US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| US6951656B2 (en) | 2000-12-22 | 2005-10-04 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6884436B2 (en) | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
| SE0100822D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method II to obtain microparticles |
| SE0100824D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method III to obtain microparticles |
| US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
| AU2002337692B2 (en) | 2001-09-26 | 2007-09-13 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
| US7112340B2 (en) | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
| WO2004080439A1 (ja) | 2003-03-12 | 2004-09-23 | Takeda Pharmaceutical Company Limited | 高濃度に活性成分を球形核に付着させた医薬組成物 |
| DE10325989A1 (de) * | 2003-06-07 | 2005-01-05 | Glatt Gmbh | Verfahren zur Herstellung von und daraus resultierende Mikropellets sowie deren Verwendung |
| US20050181052A1 (en) * | 2004-02-17 | 2005-08-18 | Patel Satishkumar A. | Lansoprazole microtablets |
| US20070207266A1 (en) * | 2006-02-15 | 2007-09-06 | Lemke Harald K | Method and apparatus for coating particulates utilizing physical vapor deposition |
| CH698658B1 (de) * | 2006-04-24 | 2009-09-30 | Mepha Ag | Orale pharmazeutische Formulierung mit schneller Freisetzung für Pyridylmethylsulfinyl-Benzimidazole. |
| US20090087569A1 (en) * | 2007-09-27 | 2009-04-02 | Fenchem Enterprises Ltd. | Methods for Preparing Highly Stable Hyaluronic Acid |
| IT1401284B1 (it) * | 2010-08-06 | 2013-07-18 | Valpharma S P A | Nuove formulazioni farmaceutiche idonee per la somministrazione orale di esomeprazolo magnesio diidrato, in forma di compresse mups (multi unit pellets system). |
| US10736855B2 (en) | 2016-02-25 | 2020-08-11 | Dexcel Pharma Technologies Ltd. | Compositions comprising proton pump inhibitors |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| JPWO2021153525A1 (OSRAM) * | 2020-01-27 | 2021-08-05 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0163836B1 (de) * | 1984-04-07 | 1988-10-12 | Bayer Ag | Verfahren und Vorrichtung zur Herstellung von Granulaten |
| IL75400A (en) * | 1984-06-16 | 1988-10-31 | Byk Gulden Lomberg Chem Fab | Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same |
| GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
| DE3909455A1 (de) * | 1989-03-22 | 1990-09-27 | Hoechst Ag | Verfahren zur herstellung von wasserdispergierbaren granulaten |
| CZ289804B6 (cs) * | 1994-07-08 | 2002-04-17 | Astrazeneca Ab | Multijednotková tabletovaná dávková forma I |
| FR2725623A1 (fr) * | 1994-10-18 | 1996-04-19 | Flamel Tech Sa | Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os |
| DE19613395A1 (de) * | 1996-04-03 | 1997-10-09 | Basf Ag | Granulate hygroskopischer, wasserlöslicher Produkte |
| DE19733094A1 (de) * | 1997-07-31 | 1999-02-04 | Merck Patent Gmbh | Formulierung auf der Basis von Ascorbinsäure mit verbesserter Farbstabilität |
| DE59813833D1 (de) * | 1997-10-15 | 2007-01-11 | Merck Patent Gmbh | Herstellung eines direkt verpressbaren tablettierhilfsstoffes |
| US6174548B1 (en) * | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| ATE303809T1 (de) * | 1997-12-08 | 2005-09-15 | Altana Pharma Ag | Orale verabreichungsform enthaltend einen protonenpumpeninhbitor (z.b. pantoprazole) |
| US20060159756A1 (en) * | 1999-09-10 | 2006-07-20 | Brita Sjoblom | Method to obtain microparticles containing an H+,K+-ATP-ASE inhibitor |
| SE0100823D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method I to obtain microparticles |
| SE9903236D0 (sv) * | 1999-09-10 | 1999-09-10 | Astra Ab | Method to obtain microparticles |
| SE0100824D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method III to obtain microparticles |
| SE0100822D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method II to obtain microparticles |
-
2001
- 2001-03-09 SE SE0100822A patent/SE0100822D0/xx unknown
-
2002
- 2002-03-06 ES ES02701872T patent/ES2307722T3/es not_active Expired - Lifetime
- 2002-03-06 US US10/471,314 patent/US20040101565A1/en not_active Abandoned
- 2002-03-06 NZ NZ527997A patent/NZ527997A/en unknown
- 2002-03-06 IL IL15746702A patent/IL157467A0/xx unknown
- 2002-03-06 BR BR0207827-9A patent/BR0207827A/pt not_active IP Right Cessation
- 2002-03-06 JP JP2002571030A patent/JP2004522796A/ja active Pending
- 2002-03-06 MX MXPA03007887A patent/MXPA03007887A/es active IP Right Grant
- 2002-03-06 EP EP02701872A patent/EP1370243B1/en not_active Expired - Lifetime
- 2002-03-06 AT AT02701872T patent/ATE400253T1/de not_active IP Right Cessation
- 2002-03-06 SI SI200230729T patent/SI1370243T1/sl unknown
- 2002-03-06 DK DK02701872T patent/DK1370243T3/da active
- 2002-03-06 CA CA002440163A patent/CA2440163A1/en not_active Abandoned
- 2002-03-06 PT PT02701872T patent/PT1370243E/pt unknown
- 2002-03-06 WO PCT/SE2002/000400 patent/WO2002072071A1/en not_active Ceased
- 2002-03-06 AU AU2002235101A patent/AU2002235101B8/en not_active Ceased
- 2002-03-06 CN CNA028095987A patent/CN1507343A/zh active Pending
- 2002-03-06 DE DE60227488T patent/DE60227488D1/de not_active Expired - Fee Related
- 2002-03-06 KR KR10-2003-7011781A patent/KR20030081506A/ko not_active Ceased
-
2003
- 2003-08-25 ZA ZA200306614A patent/ZA200306614B/xx unknown
- 2003-09-08 NO NO20033966A patent/NO20033966L/no not_active Application Discontinuation
-
2007
- 2007-07-16 US US11/778,298 patent/US20080175917A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080175917A1 (en) | 2008-07-24 |
| WO2002072071A1 (en) | 2002-09-19 |
| NO20033966D0 (no) | 2003-09-08 |
| SE0100822D0 (sv) | 2001-03-09 |
| ES2307722T3 (es) | 2008-12-01 |
| DE60227488D1 (de) | 2008-08-21 |
| PT1370243E (pt) | 2008-09-16 |
| CN1507343A (zh) | 2004-06-23 |
| MXPA03007887A (es) | 2003-12-04 |
| IL157467A0 (en) | 2004-03-28 |
| AU2002235101B2 (en) | 2006-07-13 |
| EP1370243B1 (en) | 2008-07-09 |
| SI1370243T1 (sl) | 2008-12-31 |
| NO20033966L (no) | 2003-11-03 |
| JP2004522796A (ja) | 2004-07-29 |
| EP1370243A1 (en) | 2003-12-17 |
| ATE400253T1 (de) | 2008-07-15 |
| NZ527997A (en) | 2005-02-25 |
| AU2002235101B8 (en) | 2006-08-31 |
| KR20030081506A (ko) | 2003-10-17 |
| BR0207827A (pt) | 2004-03-02 |
| CA2440163A1 (en) | 2002-09-19 |
| ZA200306614B (en) | 2004-11-25 |
| US20040101565A1 (en) | 2004-05-27 |
| HK1059896A1 (en) | 2004-07-23 |
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