DK136861B - Analogifremgangsmåde til fremstilling af 5-, 6-, 7- eller 8-(2-hydroxy-3-alkylamino)propoxycarbostyriler eller syreadditionssalte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af 5-, 6-, 7- eller 8-(2-hydroxy-3-alkylamino)propoxycarbostyriler eller syreadditionssalte deraf.Info
- Publication number
- DK136861B DK136861B DK663673AA DK663673A DK136861B DK 136861 B DK136861 B DK 136861B DK 663673A A DK663673A A DK 663673AA DK 663673 A DK663673 A DK 663673A DK 136861 B DK136861 B DK 136861B
- Authority
- DK
- Denmark
- Prior art keywords
- propoxycarbostyriles
- alkylamino
- hydroxy
- preparation
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP47125857A JPS5239035B2 (no) | 1972-12-14 | 1972-12-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK136861B true DK136861B (da) | 1977-12-05 |
DK136861C DK136861C (no) | 1978-05-08 |
Family
ID=14920647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK663673AA DK136861B (da) | 1972-12-14 | 1973-12-07 | Analogifremgangsmåde til fremstilling af 5-, 6-, 7- eller 8-(2-hydroxy-3-alkylamino)propoxycarbostyriler eller syreadditionssalte deraf. |
Country Status (11)
Country | Link |
---|---|
US (1) | US3953456A (no) |
JP (1) | JPS5239035B2 (no) |
AR (1) | AR197270A1 (no) |
BE (1) | BE808593A (no) |
CA (1) | CA1022555A (no) |
CH (1) | CH589060A5 (no) |
DE (1) | DE2362278C2 (no) |
DK (1) | DK136861B (no) |
ES (1) | ES421430A1 (no) |
FR (1) | FR2210408B1 (no) |
NL (1) | NL166931C (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4022784A (en) * | 1974-01-31 | 1977-05-10 | Otsuka Pharmaceutical Company Limited | 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives |
FI58329C (fi) * | 1974-11-08 | 1981-01-12 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat |
GB1504424A (en) * | 1975-08-09 | 1978-03-22 | Beecham Group Ltd | Isoquinoline-derived aminoethers |
CH619453A5 (no) * | 1976-03-17 | 1980-09-30 | Otsuka Pharma Co Ltd | |
GB1574665A (en) * | 1976-05-08 | 1980-09-10 | Otsuka Pharma Co Ltd | 3,4-dihydrocarbostyril derivatives and process for preparing the same |
US4139537A (en) * | 1976-06-29 | 1979-02-13 | Cooper Laboratories, Inc. | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds |
NZ187452A (en) * | 1977-06-10 | 1980-05-27 | Otsuka Pharma Co Ltd | N- substituted-aminocarbonylpropoxy-carbostyrils and their preparation |
AU518814B2 (en) * | 1979-01-30 | 1981-10-22 | Otsuka Pharamaceutical Co. | Glaucoma treatment |
DE2934609A1 (de) | 1979-08-28 | 1981-03-12 | Cassella Ag, 6000 Frankfurt | Tetrahydrochinolinderivate, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische zubereitungen. |
DE3034237A1 (de) * | 1979-09-18 | 1981-04-16 | Otsuka Pharmaceutical Co. Ltd., Tokyo | Carbostyrilderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende, antihistaminisch wirkende mittel |
PH17194A (en) * | 1980-03-06 | 1984-06-19 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives,and pharmaceutical composition containing the same |
ES2048108B1 (es) * | 1992-07-17 | 1994-10-01 | Lusochimica Spa | Procedimiento para la preparacion de 5-(3-terc-butilamino-2-hidroxipropoxi)-3,4-dihidrocarboestirilo. |
EP2130828A4 (en) | 2007-02-28 | 2010-12-29 | Asahi Kasei Pharma Corp | sulfonamide |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
GB1047927A (en) * | 1964-03-09 | 1966-11-09 | Ici Ltd | Alkanolamine derivatives |
GB1079989A (en) * | 1965-09-28 | 1967-08-16 | Ici Ltd | Carbocyclic propanolamines |
-
1972
- 1972-12-14 JP JP47125857A patent/JPS5239035B2/ja not_active Expired
-
1973
- 1973-12-06 CA CA187,578A patent/CA1022555A/en not_active Expired
- 1973-12-07 DK DK663673AA patent/DK136861B/da not_active IP Right Cessation
- 1973-12-12 AR AR251483A patent/AR197270A1/es active
- 1973-12-13 BE BE138830A patent/BE808593A/xx not_active IP Right Cessation
- 1973-12-13 NL NL7317090.A patent/NL166931C/xx not_active IP Right Cessation
- 1973-12-13 ES ES421430A patent/ES421430A1/es not_active Expired
- 1973-12-14 DE DE2362278A patent/DE2362278C2/de not_active Expired
- 1973-12-14 US US05/424,965 patent/US3953456A/en not_active Expired - Lifetime
- 1973-12-14 FR FR7344825A patent/FR2210408B1/fr not_active Expired
- 1973-12-14 CH CH1751373A patent/CH589060A5/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NL166931B (nl) | 1981-05-15 |
DE2362278A1 (de) | 1974-06-20 |
US3953456A (en) | 1976-04-27 |
FR2210408A1 (no) | 1974-07-12 |
JPS5239035B2 (no) | 1977-10-03 |
CH589060A5 (no) | 1977-06-30 |
DK136861C (no) | 1978-05-08 |
FR2210408B1 (no) | 1977-03-11 |
NL166931C (nl) | 1981-10-15 |
DE2362278C2 (de) | 1983-03-24 |
ES421430A1 (es) | 1976-05-01 |
NL7317090A (no) | 1974-06-18 |
AU6338573A (en) | 1975-07-10 |
JPS4981372A (no) | 1974-08-06 |
CA1022555A (en) | 1977-12-13 |
BE808593A (fr) | 1974-03-29 |
AR197270A1 (es) | 1974-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |