DK136718B - Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyran-9-oner. - Google Patents

Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyran-9-oner.

Info

Publication number
DK136718B
DK136718B DK573174AA DK573174A DK136718B DK 136718 B DK136718 B DK 136718B DK 573174A A DK573174A A DK 573174AA DK 573174 A DK573174 A DK 573174A DK 136718 B DK136718 B DK 136718B
Authority
DK
Denmark
Prior art keywords
dibenzo
pyran
ones
preparation
analogous process
Prior art date
Application number
DK573174AA
Other languages
Danish (da)
English (en)
Other versions
DK573174A (fr
DK136718C (fr
Inventor
Robert Allen Archer
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK573174A publication Critical patent/DK573174A/da
Publication of DK136718B publication Critical patent/DK136718B/da
Application granted granted Critical
Publication of DK136718C publication Critical patent/DK136718C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Cosmetics (AREA)
DK573174AA 1973-11-05 1974-11-04 Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyran-9-oner. DK136718B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US413009A US3928598A (en) 1973-11-05 1973-11-05 Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug

Publications (3)

Publication Number Publication Date
DK573174A DK573174A (fr) 1975-07-07
DK136718B true DK136718B (da) 1977-11-14
DK136718C DK136718C (fr) 1978-04-24

Family

ID=23635412

Family Applications (1)

Application Number Title Priority Date Filing Date
DK573174AA DK136718B (da) 1973-11-05 1974-11-04 Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyran-9-oner.

Country Status (25)

Country Link
US (1) US3928598A (fr)
JP (1) JPS6033834B2 (fr)
AR (1) AR206409A1 (fr)
AT (1) AT337178B (fr)
BE (1) BE821719A (fr)
BG (1) BG25995A3 (fr)
CA (1) CA1029383A (fr)
CH (1) CH611290A5 (fr)
CS (1) CS193506B2 (fr)
DD (1) DD116229A5 (fr)
DE (1) DE2451932C2 (fr)
DK (1) DK136718B (fr)
ES (1) ES431675A1 (fr)
FR (1) FR2249663B1 (fr)
GB (1) GB1487636A (fr)
HU (1) HU169192B (fr)
IE (1) IE40025B1 (fr)
IL (1) IL45662A (fr)
NL (1) NL180979C (fr)
PH (1) PH10476A (fr)
PL (2) PL100502B1 (fr)
SE (1) SE415761B (fr)
SU (1) SU515457A3 (fr)
YU (1) YU36946B (fr)
ZA (1) ZA745794B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4051152A (en) * 1976-01-07 1977-09-27 Sharps Associates Oxo C-ring benzopyrans
US4087545A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiemetic drugs
US4087546A (en) * 1976-02-17 1978-05-02 Eli Lilly And Company Hexahydro-dibenzo[b,d]pyran-9-ones as antiasthmatic drugs
SE7704749L (sv) * 1976-05-17 1977-12-05 Pfizer Kinoliner och forfarande och mellanprodukter for framstellning derav
US4054581A (en) * 1976-07-06 1977-10-18 Eli Lilly And Company Preparation of cis-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-ones and intermediates therefor
US4102902A (en) * 1976-11-10 1978-07-25 Eli Lilly And Company Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor
US4309545A (en) * 1980-07-28 1982-01-05 Pfizer Inc. Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof
US4351833A (en) * 1980-07-28 1982-09-28 Pfizer Inc. 9-Amino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof as analgesics and anti-emetics
US5498419A (en) * 1994-06-03 1996-03-12 Pars; Harry G. Fumarate salt of 4-(diethyl-3-(1-methyloctyl)-7,8,9,10-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-ol, 4-(diethyl-amino) butyric
DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
WO2001028329A1 (fr) 1999-10-18 2001-04-26 University Of Connecticut Ligands selectifs de recepteurs (cb2) de cannabinoides peripheriques
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
AU2001296402A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
AU2002213429A1 (en) * 2000-09-28 2002-04-08 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
WO2002058636A2 (fr) * 2001-01-26 2002-08-01 University Of Connecticut Nouveaux ligands cannabimimetiques
WO2002060447A1 (fr) 2001-01-29 2002-08-08 University Of Connecticut Aminoalkylindoles cannabimimetiques selectifs d'un recepteur
EP1414775B1 (fr) * 2001-07-13 2012-12-19 The University of Connecticut Cannabinoide bicyclique
CA2464333C (fr) * 2001-10-26 2011-07-26 University Of Connecticut Heteroindanes: nouvelle classe de ligands cannabimimetiques efficaces
US20030232101A1 (en) * 2002-03-18 2003-12-18 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636058A (en) * 1966-03-25 1972-01-18 Hoffmann La Roche 7 10 - dihydro - 3 - alkyl - 6h - dibenzo(b d) pyran-6 9(8h)-diones and 5-hydroxy-7-alkyl-4-chromanones
US3507885A (en) * 1966-03-25 1970-04-21 Hoffmann La Roche 3-alkyl-6h-dibenzo(b,d)pyrans

Also Published As

Publication number Publication date
US3928598A (en) 1975-12-23
AT337178B (de) 1977-06-10
BE821719A (fr) 1975-04-30
GB1487636A (en) 1977-10-05
SU515457A3 (ru) 1976-05-25
PL94965B1 (fr) 1977-09-30
IE40025B1 (en) 1979-02-28
YU36946B (en) 1984-08-31
NL7414437A (nl) 1975-05-07
PL100502B1 (pl) 1978-10-31
CH611290A5 (fr) 1979-05-31
NL180979C (nl) 1987-06-01
ZA745794B (en) 1976-04-28
AU7329074A (en) 1976-03-18
NL180979B (nl) 1987-01-02
DD116229A5 (fr) 1975-11-12
FR2249663B1 (fr) 1978-03-24
FR2249663A1 (fr) 1975-05-30
SE7413832L (fr) 1975-05-06
JPS5082073A (fr) 1975-07-03
IL45662A0 (en) 1974-11-29
PH10476A (en) 1977-05-11
DE2451932A1 (de) 1975-05-07
IL45662A (en) 1978-03-10
CS193506B2 (en) 1979-10-31
HU169192B (fr) 1976-10-28
ES431675A1 (es) 1977-04-16
DK573174A (fr) 1975-07-07
DK136718C (fr) 1978-04-24
CA1029383A (fr) 1978-04-11
ATA886274A (de) 1976-10-15
YU261974A (en) 1982-06-18
IE40025L (en) 1975-05-05
JPS6033834B2 (ja) 1985-08-05
DE2451932C2 (de) 1983-09-29
BG25995A3 (bg) 1979-01-12
SE415761B (sv) 1980-10-27
AR206409A1 (es) 1976-07-23

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