DK1363951T3 - Polynukleært jern(III)kompleks med pullulanoligomerer, fremgangsmåde til dens opnåelse og farmaceutiske præparater på basis af komplekset - Google Patents

Polynukleært jern(III)kompleks med pullulanoligomerer, fremgangsmåde til dens opnåelse og farmaceutiske præparater på basis af komplekset

Info

Publication number
DK1363951T3
DK1363951T3 DK01999583T DK01999583T DK1363951T3 DK 1363951 T3 DK1363951 T3 DK 1363951T3 DK 01999583 T DK01999583 T DK 01999583T DK 01999583 T DK01999583 T DK 01999583T DK 1363951 T3 DK1363951 T3 DK 1363951T3
Authority
DK
Denmark
Prior art keywords
complex
pullulanol
oligomers
iii
obtaining
Prior art date
Application number
DK01999583T
Other languages
English (en)
Inventor
Slobodan Stankovic
Ljubomir Ilic
Suzana Ristic
Milorad Cakic
Goran Nikolic
Original Assignee
Ad Zdravlje Farmaceutsko Hemij
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ad Zdravlje Farmaceutsko Hemij filed Critical Ad Zdravlje Farmaceutsko Hemij
Application granted granted Critical
Publication of DK1363951T3 publication Critical patent/DK1363951T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0018—Pullulan, i.e. (alpha-1,4)(alpha-1,6)-D-glucan; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C12P19/10—Pullulan

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01999583T 2000-12-07 2001-12-07 Polynukleært jern(III)kompleks med pullulanoligomerer, fremgangsmåde til dens opnåelse og farmaceutiske præparater på basis af komplekset DK1363951T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
YUP076900 2000-12-07
PCT/YU2001/000031 WO2002046241A2 (en) 2000-12-07 2001-12-07 Polynuclear complex fe(iii) with pullulan oligomers, process of its obtaining, and pharmaceutical preparations on the basis of the complex

Publications (1)

Publication Number Publication Date
DK1363951T3 true DK1363951T3 (da) 2007-03-12

Family

ID=37012737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01999583T DK1363951T3 (da) 2000-12-07 2001-12-07 Polynukleært jern(III)kompleks med pullulanoligomerer, fremgangsmåde til dens opnåelse og farmaceutiske præparater på basis af komplekset

Country Status (5)

Country Link
EP (1) EP1363951B1 (da)
AU (1) AU2002220280A1 (da)
DK (1) DK1363951T3 (da)
RU (1) RU2003121403A (da)
WO (1) WO2002046241A2 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10249552A1 (de) 2002-10-23 2004-05-13 Vifor (International) Ag Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel
ES2333814T3 (es) 2005-02-09 2010-03-01 Vifor (International) Ag Uso de compuestos de complejo de hierro (iii).
GB0517077D0 (en) * 2005-08-19 2005-09-28 Isis Innovation Imaging agent
EP1757299A1 (de) * 2005-08-25 2007-02-28 Vifor (International) Ag Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung
EP1790356A1 (de) * 2005-11-24 2007-05-30 Vifor (International) Ag Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en)
WO2007081744A2 (en) 2006-01-06 2007-07-19 Luitpold Pharmaceuticals, Inc. Methods and compositions for administration of iron
GB0618524D0 (en) 2006-09-20 2006-11-01 Isis Innovation Multimeric particles
ES2556985T3 (es) 2011-01-11 2016-01-21 Capsugel Belgium Nv Nuevas cápsulas duras que comprenden pululano
CN103946019B (zh) * 2011-10-13 2016-10-05 维达西姆公司 铁-纤维组合物、其制备和用途
WO2014138016A1 (en) * 2013-03-08 2014-09-12 Vidasym, Inc. Metal ion-functional fiber component complex compositions, preparation and uses thereof
CA2932075C (en) * 2015-09-01 2020-11-17 Particle Dynamics International, Llc Iron-polysaccharide complexes and methods for the preparation thereof
US10258647B2 (en) 2015-09-01 2019-04-16 Particle Dynamics International, Llc Iron-polysaccharide complexes and methods for the preparation thereof
CA3059527A1 (en) 2017-04-14 2018-10-18 Capsugel Belgium Nv Pullulan capsules
BR112019021396A2 (pt) 2017-04-14 2020-04-28 Capsugel Belgium Nv processo para fabricação de pululano

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617463A1 (de) * 1965-11-20 1971-04-08 Bayer Ag Verfahren zur Herstellung von injizierbaren kolloidalen Eisenzubereitungen
JP5064612B2 (ja) * 1999-04-09 2012-10-31 エーエムエージー ファーマシューティカルズ，インコーポレイテッド 還元された炭水化物類及び炭水化物誘導体で被覆された熱的に安定なコロイド状酸化鉄

Also Published As

Publication number Publication date
WO2002046241A2 (en) 2002-06-13
RU2003121403A (ru) 2004-12-27
AU2002220280A1 (en) 2002-06-18
EP1363951A2 (en) 2003-11-26
WO2002046241A3 (en) 2002-08-08
EP1363951B1 (en) 2006-10-25

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