DK135808B - Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf.

Info

Publication number
DK135808B
DK135808B DK251975AA DK251975A DK135808B DK 135808 B DK135808 B DK 135808B DK 251975A A DK251975A A DK 251975AA DK 251975 A DK251975 A DK 251975A DK 135808 B DK135808 B DK 135808B
Authority
DK
Denmark
Prior art keywords
benzo
preparation
acid addition
addition salts
thiophene derivatives
Prior art date
Application number
DK251975AA
Other languages
Danish (da)
English (en)
Other versions
DK135808C (es
DK251975A (es
Inventor
Marcel Descamps
Jean Gubin
Original Assignee
Labaz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz filed Critical Labaz
Publication of DK251975A publication Critical patent/DK251975A/da
Publication of DK135808B publication Critical patent/DK135808B/da
Application granted granted Critical
Publication of DK135808C publication Critical patent/DK135808C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK251975AA 1974-06-06 1975-06-04 Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf. DK135808B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2525674A GB1456323A (en) 1974-06-06 1974-06-06 Benzothiophenes process for preparing them and pharmaceutical compositions containing the same

Publications (3)

Publication Number Publication Date
DK251975A DK251975A (es) 1975-12-07
DK135808B true DK135808B (da) 1977-06-27
DK135808C DK135808C (es) 1977-11-28

Family

ID=10224753

Family Applications (1)

Application Number Title Priority Date Filing Date
DK251975AA DK135808B (da) 1974-06-06 1975-06-04 Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf.

Country Status (20)

Country Link
US (1) US4007204A (es)
JP (1) JPS516958A (es)
AR (2) AR207152A1 (es)
AT (1) AT341517B (es)
BE (1) BE829837A (es)
CA (1) CA1030972A (es)
CH (1) CH605910A5 (es)
DE (1) DE2522655A1 (es)
DK (1) DK135808B (es)
ES (1) ES438303A1 (es)
FI (1) FI751602A (es)
GB (1) GB1456323A (es)
HU (1) HU172820B (es)
IT (1) IT1038094B (es)
NL (1) NL7504921A (es)
NO (1) NO751989L (es)
OA (1) OA05022A (es)
SE (1) SE7505482L (es)
SU (1) SU578002A3 (es)
ZA (1) ZA752871B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
AU509682B2 (en) * 1975-10-28 1980-05-22 Eli Lilly And Company 2-Aroyl-3-Phenylbenzothiophene Derivatives
US5175184A (en) * 1982-10-19 1992-12-29 Kotobuki Seiyaku Company Limited Benzothiophene derivatives and antihyperuricemia thereof
NO174506B (no) * 1984-10-30 1994-02-07 Usv Pharma Corp Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser
US4806663A (en) * 1987-04-06 1989-02-21 The University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4851554A (en) * 1987-04-06 1989-07-25 University Of Tennessee Research Corporation Certain 3-substituted 2-alkyl benzofuran derivatives
US4912642A (en) * 1987-09-03 1990-03-27 The Boeing Company Coordinated engine autothrottle
AU2543388A (en) * 1987-09-30 1989-04-18 University Of Tennessee Research Corporation, The Certain 3-substituted 2-alkyl benzothiophene derivatives
US4831156A (en) * 1987-09-30 1989-05-16 The University Of Tennessee Research Corp. 3-substituted 2-alkyl indole derivatives
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
DE69525763T2 (de) * 1994-04-11 2002-10-02 Chugai Pharmaceutical Co Ltd 4,6-DI-t-BUTYL-2,3-DIHYDROBENZOTHIOPHENE, DIE LDL OXIDATION HEMMEN
CO4410190A1 (es) * 1994-09-19 1997-01-09 Lilly Co Eli 3-[4-(2-AMINOETOXI)-BENZOIL]-2-ARIL-6-HIDROXIBENZO [b] TIOFENO CRISTALINO
US6417199B1 (en) * 1995-03-10 2002-07-09 Eli Lilly And Company 3-benzyl-benzothiophenes
US6653328B1 (en) * 1995-03-10 2003-11-25 Eli Lilly And Company 3-benzyl-benzothiophenes
CA2236007A1 (en) * 1995-10-31 1997-07-17 Gerald Floyd Smith Antithrombotic diamines
CA2249406A1 (en) * 1996-03-19 1997-09-25 Eli Lilly And Company Synthesis of 3-¬4-(2-aminoethoxy)-benzoyl|-2-aryl-6-hydroxy-benzo¬b|thiophenes
CN1254280A (zh) * 1997-04-30 2000-05-24 伊莱利利公司 用于制备取代的苯并[b]噻吩的区域选择性烷基化方法
JP2002514217A (ja) 1997-04-30 2002-05-14 イーライ・リリー・アンド・カンパニー 抗血栓物質
JP2001522373A (ja) 1997-04-30 2001-11-13 イーライ・リリー・アンド・カンパニー 抗血栓剤
ES2232946T3 (es) 1997-04-30 2005-06-01 Eli Lilly And Company Agentes antitromboticos.
JP2002513415A (ja) 1997-04-30 2002-05-08 イーライ・リリー・アンド・カンパニー 抗血栓剤
US6284756B1 (en) 1998-04-30 2001-09-04 Eli Lilly And Company Antithrombotic agents
EP0997460B1 (en) * 1998-10-28 2002-12-11 Eli Lilly And Company Benzothiophene compounds as antithrombotic agents and intermediates
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
EA025307B1 (ru) * 2010-08-06 2016-12-30 Тасли Фармасьютикал Груп Ко., Лтд. Применение медицинской композиции в приготовлении лекарственного средства для вторичной профилактики ишемической болезни сердца (ибс) у пациентов с диагнозом стенокардия ii или iii степени по классификации канадского кардиоваскулярного общества

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3514465A (en) * 1966-12-30 1970-05-26 Degussa Certain thiazolyl- and pyridinylaminoketones
US3706747A (en) * 1970-06-05 1972-12-19 Pfizer Benzothieno(3,2-d)- and benzofuro(3,2-d)pyrimidines

Also Published As

Publication number Publication date
NO751989L (es) 1975-12-09
SE7505482L (sv) 1975-12-08
BE829837A (fr) 1975-12-04
ES438303A1 (es) 1977-01-16
US4007204A (en) 1977-02-08
ATA431175A (de) 1977-06-15
CA1030972A (en) 1978-05-09
CH605910A5 (es) 1978-10-13
AR210265A1 (es) 1977-07-15
HU172820B (hu) 1978-12-28
NL7504921A (nl) 1975-12-09
JPS516958A (en) 1976-01-20
IT1038094B (it) 1979-11-20
AR207152A1 (es) 1976-09-15
OA05022A (fr) 1980-12-31
ZA752871B (en) 1976-04-28
AT341517B (de) 1978-02-10
FI751602A (es) 1975-12-07
DK135808C (es) 1977-11-28
SU578002A3 (ru) 1977-10-25
DK251975A (es) 1975-12-07
AU8102275A (en) 1976-11-11
DE2522655A1 (de) 1975-12-18
GB1456323A (en) 1976-11-24

Similar Documents

Publication Publication Date Title
DK135808B (da) Analogifremgangsmåde til fremstilling af benzo(b)thiophen-derivater eller syreadditionssalte deraf.
DK140840B (da) Analogifremgangsmåde til fremstilling af benzimidazolderivater eller syreadditionssalte deraf.
DK140430B (da) Analogifremgangsmåde til fremstilling af 3-aryloxy-3-phenylpropylaminer eller syreadditionssalte heraf.
DK138076B (da) Analogifremgangsmåde til fremstilling af indolderivater eller syreadditionssalte deraf.
DK150512C (da) Analogifremgangsmaade til fremstilling af 3-quino-lincarboxylsyrederivater eller syreadditionssalte deraf
DK352875A (da) Fremgangsmade til fremstilling af 5,9-betadisubstituerede 2-tetrahydrofurfuryl-6,7-benzomorphaner eller syreadditionssalte heraf
DK137835B (da) Analogifremgangsmåde til fremstilling af thienothiazinderivater.
DK139358B (da) Analogifremgangsmåde til fremstilling af vincaminderivater eller syreadditionssalte deraf.
DK139580B (da) Analogifremgangsmåde til fremstilling af additionssalte af piperidylindolderivater.
DK130213B (da) Analogifremgangsmåde til fremstilling af 9-(4-piperidyliden) thioxanthenderivater eller syreadditionssalte deraf.
DK138321B (da) Analogifremgangsmåde til fremstilling af 5-halogen-2,3-kresotinsyrederivater.
DK137679B (da) Analogifremgangsmåde til fremstilling af thienotriazoldiazepinderivater eller syreadditionssalte deraf.
DK137953B (da) Analogifremgangsmåde til fremstilling af amidoximderivater eller syreadditionssalte deraf.
DK136529B (da) Analogifremgangsmåde til fremstilling af benzofuranderivater.
DK144697C (da) Analogifremgangsmaade til fremstilling af 3,4-dihydrocarbostyrilderivater eller syreadditionssalte deraf
DK139574B (da) Analogifremgangsmåde til fremstilling af terpeno-phenoxy-alkylaminer eller syreadditionssalte deraf.
DK131857B (da) Analogifremgangsmåde til fremstilling af 4-hydroxymethyl-1-phthalazonderivater eller syreadditionssalte deraf.
DK140590B (da) Analogifremgangsmåde til fremstilling af 4-cyclopropylmethylenoxy-3-chlorphenyleddikesyre eller salte heraf.
DK130344B (da) Analogifremgangsmåde til fremstilling af benzofuranderivater eller syreadditionssalte deraf.
DK139682B (da) Analogifremgangsmåde til fremstilling af eburnameninderivater.
DK140841B (da) Analogifremgangsmåde til fremstilling af isoquinolinderivater eller salte deraf.
DK111094B (da) Fremgangsmåde til fremstilling af basisk substituerede benzo (b)tiofenderivater eller syreadditionssalte deraf.
DK140670B (da) Analogifremgangsmåde til fremstilling af ergopeptinderivater.
DK138993B (da) Analogifremgangsmåde til fremstilling af indolo(1,7-ab)(1)benzazepinderivater eller syreadditionssalte deraf.
DK138540B (da) Analogifremgangsmåde til fremstilling af benzhydryloxyalkylaminderivater eller farmaceutisk acceptable syreadditionssalte deraf.