DK132739B - Fremgangsmade til udvinding af et humant carcinoembryonisk antigenmateriale og eventuelt de enkelte komponenter a og/eller b heraf - Google Patents

Fremgangsmade til udvinding af et humant carcinoembryonisk antigenmateriale og eventuelt de enkelte komponenter a og/eller b heraf

Info

Publication number
DK132739B
DK132739B DK260171AA DK260171A DK132739B DK 132739 B DK132739 B DK 132739B DK 260171A A DK260171A A DK 260171AA DK 260171 A DK260171 A DK 260171A DK 132739 B DK132739 B DK 132739B
Authority
DK
Denmark
Prior art keywords
extraction
procedure
individual components
carcinoembryonic antigen
human carcinoembryonic
Prior art date
Application number
DK260171AA
Other languages
English (en)
Other versions
DK132739C (da
Inventor
H J Hansen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to DK377573A priority Critical patent/DK138357B/da
Priority to DK377673A priority patent/DK140375B/da
Publication of DK132739B publication Critical patent/DK132739B/da
Application granted granted Critical
Publication of DK132739C publication Critical patent/DK132739C/da

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00Ion-exchange processes in general; Apparatus therefor
    • B01J47/02Column or bed processes
    • B01J47/04Mixed-bed processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1048Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell determinant being a carcino embryonic antigen
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26Cation exchangers for chromatographic processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J47/00Ion-exchange processes in general; Apparatus therefor
    • B01J47/014Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007Carcino-embryonic Antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57473Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
    • Y10S436/813Cancer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/825Pretreatment for removal of interfering factors from sample
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806Antigenic peptides or proteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/828Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK260171A 1970-06-01 1971-05-28 Fremgangsmade til udvinding af et humant carcinoembryonins anfremgangsmade til udvinding af et humant carcinoembryonisk antigenmateriale og eventyelt de enkelte komponenter a og/ellertigenmateriale og eventuelt de enkelte komponenter a og/eller b heraf DK132739C (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK377573A DK138357B (da) 1970-06-01 1973-07-06 Fremgangsmåde til udvinding af humant carcinoembryonisk antigenmateriale og eventuelt de enkelte komponenter A og/eller B deraf.
DK377673A DK140375B (da) 1970-06-01 1973-07-06 Carcinoembryonisk antigenkomponent til anvendelse som reagens ved en diagnostisk testmetode.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4252670A 1970-06-01 1970-06-01
US11028871A 1971-01-27 1971-01-27
US13340471A 1971-04-12 1971-04-12

Publications (2)

Publication Number Publication Date
DK132739B true DK132739B (da) 1976-02-02
DK132739C DK132739C (da) 1976-07-12

Family

ID=27366145

Family Applications (1)

Application Number Title Priority Date Filing Date
DK260171A DK132739C (da) 1970-06-01 1971-05-28 Fremgangsmade til udvinding af et humant carcinoembryonins anfremgangsmade til udvinding af et humant carcinoembryonisk antigenmateriale og eventyelt de enkelte komponenter a og/ellertigenmateriale og eventuelt de enkelte komponenter a og/eller b heraf

Country Status (13)

Country Link
US (1) US3697638A (da)
JP (1) JPS542247B1 (da)
BE (1) BE767801A (da)
CA (1) CA965351A (da)
CH (4) CH596554A5 (da)
DE (1) DE2126680B2 (da)
DK (1) DK132739C (da)
FR (1) FR2095644A5 (da)
GB (4) GB1358828A (da)
IL (1) IL36950A (da)
IT (1) IT998033B (da)
NL (1) NL161457C (da)
SE (5) SE400083B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3867363A (en) * 1970-06-01 1975-02-18 Hans John Hansen Carcinoembryonic antigens
US3956258A (en) * 1972-05-12 1976-05-11 Hoffmann-La Roche Inc. Carcinoembryonic antigens
CH583036A5 (da) * 1972-05-12 1976-12-31 Hoffmann La Roche
ZA723264B (en) * 1972-10-13 1974-08-28 H Van Til Improvements in toys
US3867518A (en) * 1973-03-09 1975-02-18 Hoffmann La Roche Radioimmunoassay for insulin
US3927193A (en) * 1973-05-18 1975-12-16 Hoffmann La Roche Localization of tumors by radiolabelled antibodies
US4022876A (en) * 1973-06-21 1977-05-10 Stanford Research Institute Mass spectrometric immunoassay
US4132769A (en) * 1974-10-30 1979-01-02 Osther Kurt B Cancer antigen, cancer therapy, and cancer diagnosis
US4152410A (en) * 1975-09-03 1979-05-01 Eisai Co., Ltd. Diagnosis reagent for neoplasm and method for diagnosis of neoplasm
US4132767A (en) * 1976-04-05 1979-01-02 Eisai Co., Ltd. Preparation of α-L antibody, purification of α-L antigen and reagent for detection of α-L antibody and α-L antigen
US4144031A (en) * 1976-04-19 1979-03-13 International Radioimmune Systems, Inc. Cell test for detecting human chorionic gonadotropin
US4140753A (en) * 1976-04-30 1979-02-20 Scripps Clinic & Research Foundation Diagnostic method and reagent
US4145336A (en) * 1976-04-30 1979-03-20 Scripps Clinic And Research Foundation Carcinoembryonic antigen isomer
US4146603A (en) * 1977-02-18 1979-03-27 Research Corporation Tumor specific glycoproteins and method for detecting tumorigenic cancers
US4234476A (en) * 1978-03-07 1980-11-18 Research Corporation Application of protein-protein interaction as an assay for the detection of cancer
US4228127A (en) * 1978-10-06 1980-10-14 International Radioimmune Systems, Inc. Kit for detecting human chorionic gonadotropin
US4241044A (en) * 1978-12-28 1980-12-23 Abbott Laboratories Method of diagnosing cancer by detecting elevated anti-T antibody activity
US4349528A (en) * 1979-11-21 1982-09-14 The Wistar Institute Monocolonal hybridoma antibody specific for high molecular weight carcinoembryonic antigen
US4299815A (en) * 1980-02-08 1981-11-10 Hoffmann-La Roche Inc. Carcinoembryonic antigen determination
US4578349A (en) * 1982-04-08 1986-03-25 Abbott Laboratories Immunoassay for carcinoembryonic antigen (CEA)
DE3276968D1 (en) * 1982-08-09 1987-09-17 Centocor Inc Immunoassay for carbohydrate antigenic determinant
DK557483A (da) * 1982-12-06 1984-06-07 Hoffmann La Roche Fremgangsmaade til bestemmelse af cea
US4962187A (en) * 1984-11-28 1990-10-09 Cota Biotech Common antigen for colorectal and mucinous ovarian tumors and process for isolating the same
US5030559A (en) * 1986-04-01 1991-07-09 Board Of Regents, The University Of Texas System Methods and compositions for the identification of metastatic human tumors
US6013772A (en) * 1986-08-13 2000-01-11 Bayer Corporation Antibody preparations specifically binding to unique determinants of CEA antigens or fragments thereof and use of the antibody preparations in immunoassays
US5217903A (en) * 1990-05-15 1993-06-08 Trustees Of Boston University Measuring connective tissue breakdown products in body fluids

Also Published As

Publication number Publication date
IL36950A0 (en) 1971-11-29
SE7413187L (da) 1974-10-18
JPS542247B1 (da) 1979-02-05
GB1358828A (en) 1974-07-03
FR2095644A5 (da) 1972-02-11
IL36950A (en) 1975-04-25
DE2126680B2 (de) 1980-10-09
GB1356911A (en) 1974-06-19
GB1358827A (en) 1974-07-03
SE7413185L (da) 1974-10-18
US3697638A (en) 1972-10-10
NL161457C (nl) 1980-02-15
CH596554A5 (da) 1978-03-15
CH606067A5 (da) 1978-10-13
DE2126680A1 (de) 1971-12-09
GB1356912A (en) 1974-06-19
DK132739C (da) 1976-07-12
SE419482B (sv) 1981-08-03
IT998033B (it) 1976-01-20
CH604665A5 (da) 1978-09-15
CH595636A5 (da) 1978-02-15
SE397139B (sv) 1977-10-17
SE7413184L (da) 1974-10-18
BE767801A (fr) 1971-11-29
SE419481B (sv) 1981-08-03
SE7413186L (da) 1974-10-18
CA965351A (en) 1975-04-01
NL7107499A (da) 1971-12-03
SE400083B (sv) 1978-03-13
SE421425B (sv) 1981-12-21
NL161457B (nl) 1979-09-17

Similar Documents

Publication Publication Date Title
DK132739B (da) Fremgangsmade til udvinding af et humant carcinoembryonisk antigenmateriale og eventuelt de enkelte komponenter a og/eller b heraf
SE7708341L (sv) Analysforfarande och -apparat
BE754242A (fr) Diamino-s-triazines et dinitro-s-triazines
DK145283C (da) Vaccine til forhindring af graviditet og fremgangsmaade til fremstilling af vaccinen
IT942440B (it) Protesi ossea
SE389190B (sv) Raketutskjutningsanordning
AT329175B (de) Leibstutz- und huftgurtel
DK143454C (da) Fremgangsmaade til ekstraktion af zinkferritholdigt materiale
DK131598B (da) Lynlås og fremgangsmåde til fremstilling af samme.
IT942878B (it) Procedimento per la cucitura di calzemaglia o cosiddetti collants senza tasselli e apparecchio per la sua attuazion
CH527285A (de) Vorrichtung zur Übergabe und Verdichtung von Fasermaterial
RO69019A (ro) Material preimpregnat si procedeu de realizare a acestuia
BE775441A (fr) Composes diglycidyliques et melanges durcissables qui en contiennent
DK144693C (da) Forbindsstof og fremgangsmaade til fremstilling deraf
BE793659A (fr) Diglycidylimidazolidones et melanges durcissables qui en renferment
TR17380A (tr) Ueruen ve usul
DK28077A (da) Fremgangsmade til ekstraktion af antigen og anvendelse deraf samt produkter fremstillet deraf
IT974264B (it) Procedimento e dispositivo per lo sviluppo di materiale fotosensi bile
IT988618B (it) Procedimento e apparecchiatura c arburants et lubrificant
DK135369B (da) Fremgangsmade til vakuumpakning af kod og veskeabsorberende indleg til udovelse af fremgangsmaden
IT976334B (it) Fotomaschera e procedimento per ot tenerla
DK133129C (da) Fremgangsmade til udvinding af et histamihopexisk glycoprotein af human serisk oprindelse
DK131599B (da) Fremgangsmåde til fremstilling af skruelinieformede låsestrimler til lynlåse og et apparat til udøvelse af fremgangsmåden.
BE785958A (nl) Thermografische registreerwerkwijze en daarbij gebruikt materiaal
IT982046B (it) Procedimento e dispositivo per scavare ardesia

Legal Events

Date Code Title Description
PBP Patent lapsed