DK1325001T3 - New anticholinergics for use as a drug as well as methods for their preparation - Google Patents

New anticholinergics for use as a drug as well as methods for their preparation

Info

Publication number
DK1325001T3
DK1325001T3 DK01982374T DK01982374T DK1325001T3 DK 1325001 T3 DK1325001 T3 DK 1325001T3 DK 01982374 T DK01982374 T DK 01982374T DK 01982374 T DK01982374 T DK 01982374T DK 1325001 T3 DK1325001 T3 DK 1325001T3
Authority
DK
Denmark
Prior art keywords
drug
preparation
methods
well
anticholinergics
Prior art date
Application number
DK01982374T
Other languages
Danish (da)
Inventor
Michael Paul Pieper
Helmut Meissner
Gerd Morschhaeuser
Gerald Pohl
Richard Reichl
Georg Speck
Rolf Banholzer
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK1325001T3 publication Critical patent/DK1325001T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
DK01982374T 2000-10-14 2001-09-28 New anticholinergics for use as a drug as well as methods for their preparation DK1325001T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10050994A DE10050994A1 (en) 2000-10-14 2000-10-14 New diphenylalkanoic acid azabicyclooctane ester quaternary salts useful as anticholinergic agents, especially in treatment of asthma and chronic obstructive pulmonary disease
PCT/EP2001/011226 WO2002032899A1 (en) 2000-10-14 2001-09-28 Novel anticholinergic agents that can be used as medicaments and method for the production thereof

Publications (1)

Publication Number Publication Date
DK1325001T3 true DK1325001T3 (en) 2004-06-21

Family

ID=7659808

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01982374T DK1325001T3 (en) 2000-10-14 2001-09-28 New anticholinergics for use as a drug as well as methods for their preparation

Country Status (38)

Country Link
EP (2) EP1382606A3 (en)
JP (2) JP4109106B2 (en)
KR (1) KR100830359B1 (en)
CN (1) CN1275962C (en)
AR (1) AR035589A1 (en)
AT (1) ATE259805T1 (en)
AU (2) AU1397502A (en)
BG (1) BG66225B1 (en)
BR (1) BR0114635A (en)
CA (1) CA2425557C (en)
DE (2) DE10050994A1 (en)
DK (1) DK1325001T3 (en)
EA (1) EA005816B1 (en)
EC (1) ECSP034542A (en)
EE (1) EE05179B1 (en)
ES (1) ES2215147T3 (en)
HK (1) HK1060566A1 (en)
HR (1) HRP20030278B1 (en)
HU (1) HUP0301203A3 (en)
IL (2) IL155334A0 (en)
ME (1) MEP39908A (en)
MX (1) MXPA03003160A (en)
MY (1) MY127144A (en)
NO (1) NO328207B1 (en)
NZ (1) NZ525836A (en)
PE (1) PE20020433A1 (en)
PL (1) PL207311B1 (en)
PT (1) PT1325001E (en)
RS (1) RS50464B (en)
SA (1) SA01220414B1 (en)
SI (1) SI1325001T1 (en)
SK (1) SK287138B6 (en)
TR (1) TR200400376T4 (en)
TW (1) TWI306098B (en)
UA (1) UA73804C2 (en)
UY (1) UY26958A1 (en)
WO (1) WO2002032899A1 (en)
ZA (1) ZA200302914B (en)

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DE10216429A1 (en) * 2002-04-12 2003-10-23 Boehringer Ingelheim Pharma Synergistic medicaments for treating inflammatory or obstructive respiratory tract diseases, containing quaternized scopine ester anticholinergic agent and steroid, e.g. budesonide
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Also Published As

Publication number Publication date
TR200400376T4 (en) 2004-03-22
BG107688A (en) 2003-09-30
CN1468236A (en) 2004-01-14
EP1382606A2 (en) 2004-01-21
CA2425557C (en) 2007-11-13
EE200300151A (en) 2003-06-16
CA2425557A1 (en) 2003-04-11
HUP0301203A3 (en) 2006-05-29
AU2002213975B2 (en) 2006-11-09
UY26958A1 (en) 2002-06-20
SI1325001T1 (en) 2004-08-31
DE50101524D1 (en) 2004-03-25
ATE259805T1 (en) 2004-03-15
RS50464B (en) 2010-03-02
HUP0301203A2 (en) 2003-10-28
EP1382606A3 (en) 2004-10-13
HK1060566A1 (en) 2004-08-13
HRP20030278B1 (en) 2006-02-28
NO328207B1 (en) 2010-01-11
PE20020433A1 (en) 2002-06-28
UA73804C2 (en) 2005-09-15
JP2008120834A (en) 2008-05-29
AU1397502A (en) 2002-04-29
EE05179B1 (en) 2009-06-15
AR035589A1 (en) 2004-06-16
IL155334A0 (en) 2003-11-23
YU29503A (en) 2006-03-03
PL360673A1 (en) 2004-09-20
ZA200302914B (en) 2003-11-14
SA01220414B1 (en) 2007-01-20
TWI306098B (en) 2009-02-11
PL207311B1 (en) 2010-11-30
KR100830359B1 (en) 2008-05-20
EP1325001A1 (en) 2003-07-09
EA005816B1 (en) 2005-06-30
JP4109106B2 (en) 2008-07-02
IL155334A (en) 2009-02-11
PT1325001E (en) 2004-07-30
EA200300459A1 (en) 2003-10-30
ECSP034542A (en) 2003-06-25
WO2002032899A1 (en) 2002-04-25
BR0114635A (en) 2004-02-10
MEP39908A (en) 2011-02-10
NO20031693L (en) 2003-05-28
CN1275962C (en) 2006-09-20
DE10050994A1 (en) 2002-04-18
SK4352003A3 (en) 2003-08-05
ES2215147T3 (en) 2004-10-01
MXPA03003160A (en) 2005-09-09
MY127144A (en) 2006-11-30
HRP20030278A2 (en) 2005-02-28
NO20031693D0 (en) 2003-04-11
NZ525836A (en) 2004-09-24
KR20030041165A (en) 2003-05-23
EP1325001B1 (en) 2004-02-18
BG66225B1 (en) 2012-06-29
JP2004511557A (en) 2004-04-15
SK287138B6 (en) 2010-01-07

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