MEP39908A - Novel anticholinergic agents that can be used as medicaments and method for the production thereof - Google Patents

Novel anticholinergic agents that can be used as medicaments and method for the production thereof

Info

Publication number
MEP39908A
MEP39908A MEP-399/08A MEP39908A MEP39908A ME P39908 A MEP39908 A ME P39908A ME P39908 A MEP39908 A ME P39908A ME P39908 A MEP39908 A ME P39908A
Authority
ME
Montenegro
Prior art keywords
medicaments
production
anticholinergic agents
novel anticholinergic
novel
Prior art date
Application number
MEP-399/08A
Other languages
Bosnian (bs)
Inventor
Helmut Meissner
Gerd Morschhaeuser
Michael Paul Pieper
Gerald Pohl
Richard Reichl
Georg Speck
Rolf Banholzer
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MEP39908A publication Critical patent/MEP39908A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Predmetni pronalazak se odnosi na nove antiholinergike opšte formule (I) u kojoj A, X i radikali R1, R2, R3, R4, R5, R6 i R7 mogu imati ista značenja koja su navedena u patentnim zahtjevima i opisu pronalaska, na postupak za njihovo dobijanje, kao i na njihovu primjenu kao ljekovi.The present invention relates to novel anticholinergics of general formula (I) in which A, X and the radicals R1, R2, R3, R4, R5, R6 and R7 may have the same meanings as stated in the claims and the description of the invention, to a process for their obtaining, as well as on their application as drugs.

MEP-399/08A 2000-10-14 2001-09-28 Novel anticholinergic agents that can be used as medicaments and method for the production thereof MEP39908A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10050994A DE10050994A1 (en) 2000-10-14 2000-10-14 New diphenylalkanoic acid azabicyclooctane ester quaternary salts useful as anticholinergic agents, especially in treatment of asthma and chronic obstructive pulmonary disease
YUP-295/03A RS50464B (en) 2000-10-14 2001-09-28 Novel anticholinergic agents that can be used as medicaments and method for the production thereof
PCT/EP2001/011226 WO2002032899A1 (en) 2000-10-14 2001-09-28 Novel anticholinergic agents that can be used as medicaments and method for the production thereof

Publications (1)

Publication Number Publication Date
MEP39908A true MEP39908A (en) 2011-02-10

Family

ID=7659808

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-399/08A MEP39908A (en) 2000-10-14 2001-09-28 Novel anticholinergic agents that can be used as medicaments and method for the production thereof

Country Status (38)

Country Link
EP (2) EP1382606A3 (en)
JP (2) JP4109106B2 (en)
KR (1) KR100830359B1 (en)
CN (1) CN1275962C (en)
AR (1) AR035589A1 (en)
AT (1) ATE259805T1 (en)
AU (2) AU1397502A (en)
BG (1) BG66225B1 (en)
BR (1) BR0114635A (en)
CA (1) CA2425557C (en)
DE (2) DE10050994A1 (en)
DK (1) DK1325001T3 (en)
EA (1) EA005816B1 (en)
EC (1) ECSP034542A (en)
EE (1) EE05179B1 (en)
ES (1) ES2215147T3 (en)
HK (1) HK1060566A1 (en)
HR (1) HRP20030278B1 (en)
HU (1) HUP0301203A3 (en)
IL (2) IL155334A0 (en)
ME (1) MEP39908A (en)
MX (1) MXPA03003160A (en)
MY (1) MY127144A (en)
NO (1) NO328207B1 (en)
NZ (1) NZ525836A (en)
PE (1) PE20020433A1 (en)
PL (1) PL207311B1 (en)
PT (1) PT1325001E (en)
RS (1) RS50464B (en)
SA (1) SA01220414B1 (en)
SI (1) SI1325001T1 (en)
SK (1) SK287138B6 (en)
TR (1) TR200400376T4 (en)
TW (1) TWI306098B (en)
UA (1) UA73804C2 (en)
UY (1) UY26958A1 (en)
WO (1) WO2002032899A1 (en)
ZA (1) ZA200302914B (en)

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Also Published As

Publication number Publication date
TR200400376T4 (en) 2004-03-22
BG107688A (en) 2003-09-30
CN1468236A (en) 2004-01-14
EP1382606A2 (en) 2004-01-21
CA2425557C (en) 2007-11-13
EE200300151A (en) 2003-06-16
CA2425557A1 (en) 2003-04-11
HUP0301203A3 (en) 2006-05-29
AU2002213975B2 (en) 2006-11-09
UY26958A1 (en) 2002-06-20
SI1325001T1 (en) 2004-08-31
DE50101524D1 (en) 2004-03-25
ATE259805T1 (en) 2004-03-15
RS50464B (en) 2010-03-02
HUP0301203A2 (en) 2003-10-28
EP1382606A3 (en) 2004-10-13
HK1060566A1 (en) 2004-08-13
HRP20030278B1 (en) 2006-02-28
NO328207B1 (en) 2010-01-11
PE20020433A1 (en) 2002-06-28
UA73804C2 (en) 2005-09-15
JP2008120834A (en) 2008-05-29
AU1397502A (en) 2002-04-29
EE05179B1 (en) 2009-06-15
AR035589A1 (en) 2004-06-16
IL155334A0 (en) 2003-11-23
YU29503A (en) 2006-03-03
PL360673A1 (en) 2004-09-20
ZA200302914B (en) 2003-11-14
SA01220414B1 (en) 2007-01-20
DK1325001T3 (en) 2004-06-21
TWI306098B (en) 2009-02-11
PL207311B1 (en) 2010-11-30
KR100830359B1 (en) 2008-05-20
EP1325001A1 (en) 2003-07-09
EA005816B1 (en) 2005-06-30
JP4109106B2 (en) 2008-07-02
IL155334A (en) 2009-02-11
PT1325001E (en) 2004-07-30
EA200300459A1 (en) 2003-10-30
ECSP034542A (en) 2003-06-25
WO2002032899A1 (en) 2002-04-25
BR0114635A (en) 2004-02-10
NO20031693L (en) 2003-05-28
CN1275962C (en) 2006-09-20
DE10050994A1 (en) 2002-04-18
SK4352003A3 (en) 2003-08-05
ES2215147T3 (en) 2004-10-01
MXPA03003160A (en) 2005-09-09
MY127144A (en) 2006-11-30
HRP20030278A2 (en) 2005-02-28
NO20031693D0 (en) 2003-04-11
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KR20030041165A (en) 2003-05-23
EP1325001B1 (en) 2004-02-18
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JP2004511557A (en) 2004-04-15
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