DK1315519T3 - Farmaceutiske sammensætninger og fremgangsmåder, der kan anvendes til behandling af cancer eller leverfibrose - Google Patents

Farmaceutiske sammensætninger og fremgangsmåder, der kan anvendes til behandling af cancer eller leverfibrose

Info

Publication number
DK1315519T3
DK1315519T3 DK01958338.4T DK01958338T DK1315519T3 DK 1315519 T3 DK1315519 T3 DK 1315519T3 DK 01958338 T DK01958338 T DK 01958338T DK 1315519 T3 DK1315519 T3 DK 1315519T3
Authority
DK
Denmark
Prior art keywords
methods
pharmaceutical compositions
liver fibrosis
treat cancer
mammalian tissue
Prior art date
Application number
DK01958338.4T
Other languages
English (en)
Inventor
Stela Gengrovitch
Gera Neufeld
Gal Akiri
Zahava Vadasz
Original Assignee
Technion Res & Dev Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Res & Dev Foundation filed Critical Technion Res & Dev Foundation
Application granted granted Critical
Publication of DK1315519T3 publication Critical patent/DK1315519T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03013—Protein-lysine 6-oxidase (1.4.3.13), i.e. lysyl-oxidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK01958338.4T 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder, der kan anvendes til behandling af cancer eller leverfibrose DK1315519T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22373900P 2000-08-08 2000-08-08
PCT/IL2001/000728 WO2002011667A2 (en) 2000-08-08 2001-08-07 Pharmaceutical compositions and methods useful for modulating angiogenesis

Publications (1)

Publication Number Publication Date
DK1315519T3 true DK1315519T3 (da) 2011-04-11

Family

ID=22837793

Family Applications (4)

Application Number Title Priority Date Filing Date
DK08020754.1T DK2078531T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder, der kan anvendes til modulering af angiogenese
DK10012457.7T DK2359853T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder, der er anvendelige til at modulere antiogenese
DK10012458.5T DK2359854T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder egnet til modulering af angiogenese
DK01958338.4T DK1315519T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder, der kan anvendes til behandling af cancer eller leverfibrose

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DK08020754.1T DK2078531T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder, der kan anvendes til modulering af angiogenese
DK10012457.7T DK2359853T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder, der er anvendelige til at modulere antiogenese
DK10012458.5T DK2359854T3 (da) 2000-08-08 2001-08-07 Farmaceutiske sammensætninger og fremgangsmåder egnet til modulering af angiogenese

Country Status (10)

Country Link
EP (4) EP2359853B1 (da)
AT (1) ATE493147T1 (da)
AU (1) AU2001280056A1 (da)
CY (3) CY1111869T1 (da)
DE (1) DE60143754D1 (da)
DK (4) DK2078531T3 (da)
ES (4) ES2437093T3 (da)
HK (3) HK1131912A1 (da)
PT (4) PT2078531E (da)
WO (1) WO2002011667A2 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
US20030224989A1 (en) * 2002-02-12 2003-12-04 Kerry Quinn Compositions and methods for treatment of osteoarthritis
FR2855968B1 (fr) 2003-06-13 2012-11-30 Coletica Stimulation de la synthese et de l'activite d'une isoforme de la lysyl oxydase-like loxl pour stimuler la formation de fibres elastiques
WO2005069975A2 (en) 2004-01-23 2005-08-04 Massachusetts Eye & Ear Infirmary Lysyl oxidase-like 1 (loxl1) and elastogenesis
WO2006128740A2 (en) * 2005-06-02 2006-12-07 Centelion Anti-vascular methods and therapies employing lysyl oxidase inhibitors
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
SI2185198T1 (sl) 2007-08-02 2015-04-30 Gilead Biologics, Inc. Inhibitorji LOX in LOXL2 ter njihova uporaba
DE102007051006A1 (de) * 2007-10-25 2009-04-30 Lanxess Deutschland Gmbh Stabile, synergistische Mischungen
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
SG2014004816A (en) 2009-08-21 2014-03-28 Gilead Biologics Inc Catalytic domains from lysyl oxidase and loxl2
CA2789022A1 (en) 2010-02-04 2011-08-11 Gilead Biologics, Inc. Antibodies that bind to lysyl oxidase-like 2 (loxl2) and methods of use therefor

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NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
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US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
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US5021404A (en) * 1988-04-20 1991-06-04 The Children's Medical Center Corporation Angiostatic collagen modulators
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DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
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Also Published As

Publication number Publication date
PT2078531E (pt) 2012-08-06
CY1113142T1 (el) 2016-04-13
HK1161115A1 (en) 2012-08-24
DE60143754D1 (de) 2011-02-10
ES2358581T3 (es) 2011-05-12
WO2002011667A3 (en) 2003-03-27
CY1111869T1 (el) 2015-11-04
EP1315519B1 (en) 2010-12-29
EP2359853A1 (en) 2011-08-24
EP1315519A4 (en) 2005-09-14
ES2440932T3 (es) 2014-01-31
PT1315519E (pt) 2011-03-17
HK1161113A1 (en) 2012-08-24
PT2359853E (pt) 2013-12-26
WO2002011667A2 (en) 2002-02-14
DK2359854T3 (da) 2013-11-04
EP2078531A2 (en) 2009-07-15
EP2359853B1 (en) 2013-11-06
DK2359853T3 (da) 2013-12-09
HK1131912A1 (en) 2010-02-12
EP2078531A3 (en) 2010-01-20
EP2359854B1 (en) 2013-10-09
ES2387329T3 (es) 2012-09-20
CY1114734T1 (el) 2016-12-14
EP1315519A2 (en) 2003-06-04
PT2359854E (pt) 2013-11-22
ES2437093T3 (es) 2014-01-08
ATE493147T1 (de) 2011-01-15
EP2078531B1 (en) 2012-05-30
DK2078531T3 (da) 2012-09-10
EP2359854A1 (en) 2011-08-24
AU2001280056A1 (en) 2002-02-18

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