DK129234B - Fremgangsmåde til fremstilling af levo-1-n-butyl-2',6'-pipecoloxylidid. - Google Patents

Fremgangsmåde til fremstilling af levo-1-n-butyl-2',6'-pipecoloxylidid.

Info

Publication number
DK129234B
DK129234B DK226968AA DK226968A DK129234B DK 129234 B DK129234 B DK 129234B DK 226968A A DK226968A A DK 226968AA DK 226968 A DK226968 A DK 226968A DK 129234 B DK129234 B DK 129234B
Authority
DK
Denmark
Prior art keywords
pipecoloxylidide
levo
butyl
preparation
Prior art date
Application number
DK226968AA
Other languages
Danish (da)
English (en)
Other versions
DK129234C (de
Inventor
F Luduena
B Tullar
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of DK129234B publication Critical patent/DK129234B/da
Application granted granted Critical
Publication of DK129234C publication Critical patent/DK129234C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK226968AA 1967-05-18 1968-05-16 Fremgangsmåde til fremstilling af levo-1-n-butyl-2',6'-pipecoloxylidid. DK129234B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63927767A 1967-05-18 1967-05-18

Publications (2)

Publication Number Publication Date
DK129234B true DK129234B (da) 1974-09-16
DK129234C DK129234C (de) 1975-02-03

Family

ID=24563449

Family Applications (1)

Application Number Title Priority Date Filing Date
DK226968AA DK129234B (da) 1967-05-18 1968-05-16 Fremgangsmåde til fremstilling af levo-1-n-butyl-2',6'-pipecoloxylidid.

Country Status (13)

Country Link
AT (2) AT286298B (de)
BE (1) BE715188A (de)
CH (1) CH498834A (de)
DE (1) DE1770408C3 (de)
DK (1) DK129234B (de)
ES (1) ES354352A1 (de)
FI (1) FI50333C (de)
FR (2) FR1583872A (de)
GB (1) GB1180712A (de)
IL (1) IL29958A (de)
NL (1) NL6806995A (de)
NO (1) NO124540B (de)
SE (1) SE341404B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU560367B2 (en) * 1983-08-01 1987-04-02 Astra Lakemedel Aktiebolag L-n-n-propylpipecolic acid-2,6-xylidide and method for preparing the same
SE451840B (sv) * 1986-01-03 1987-11-02 Astra Laekemedel Ab Optiskt rent monohydrat av s-(-)-1-propyl-2',6'-pipekoloxylididhydroklorid, sett att framstella denna och farmaceutiska beredningar for lokalbedovning
CA2200355C (en) * 1994-10-25 2007-03-06 Marianne Langston Crystallisation of levobupivacaine and analogues thereof
SE9501808D0 (sv) * 1995-05-16 1995-05-16 Astra Ab New process
KR100844336B1 (ko) * 2007-01-16 2008-07-07 하나제약 주식회사 레보부피바카인 및 이의 염산염의 신규한 제조방법
WO2014009964A1 (en) * 2012-07-11 2014-01-16 Neon Laboratories Limited Process for enantiomeric enrichment of 2 ', 6 ' - pipecoloxylidide
CN105315196A (zh) * 2015-11-28 2016-02-10 山东齐都药业有限公司 一种高纯度盐酸左布比卡因精制方法
CN109896992A (zh) * 2017-12-08 2019-06-18 武汉软件工程职业学院 制备离子液体的方法及其应用

Also Published As

Publication number Publication date
DK129234C (de) 1975-02-03
IL29958A0 (en) 1968-07-25
FR1583872A (de) 1969-12-05
NO124540B (de) 1972-05-02
CH498834A (de) 1970-11-15
NL6806995A (de) 1968-11-19
DE1770408A1 (de) 1971-10-21
FI50333C (fi) 1976-02-10
BE715188A (de) 1968-09-30
DE1770408C3 (de) 1974-11-07
DE1770408B2 (de) 1974-04-11
FI50333B (de) 1975-10-31
ES354352A1 (es) 1969-11-01
GB1180712A (en) 1970-02-11
AT286298B (de) 1970-12-10
IL29958A (en) 1971-04-28
AT284843B (de) 1970-09-25
FR8160M (de) 1970-08-24
SE341404B (de) 1971-12-27

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