DK1282690T3 - Isolation af precursorceller og anvendelse deraf til vævsreparation - Google Patents
Isolation af precursorceller og anvendelse deraf til vævsreparationInfo
- Publication number
- DK1282690T3 DK1282690T3 DK00965662T DK00965662T DK1282690T3 DK 1282690 T3 DK1282690 T3 DK 1282690T3 DK 00965662 T DK00965662 T DK 00965662T DK 00965662 T DK00965662 T DK 00965662T DK 1282690 T3 DK1282690 T3 DK 1282690T3
- Authority
- DK
- Denmark
- Prior art keywords
- precursor cells
- marker
- expressed
- detectable
- morphogenic protein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1317—Chondrocytes
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99203274 | 1999-10-06 | ||
EP99203290 | 1999-10-07 | ||
PCT/BE2000/000120 WO2001025402A1 (en) | 1999-10-06 | 2000-10-06 | Isolation of precursor cells and their use for tissue repair |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1282690T3 true DK1282690T3 (da) | 2005-02-28 |
Family
ID=26153376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00965662T DK1282690T3 (da) | 1999-10-06 | 2000-10-06 | Isolation af precursorceller og anvendelse deraf til vævsreparation |
Country Status (10)
Country | Link |
---|---|
US (2) | US7863045B2 (da) |
EP (1) | EP1282690B9 (da) |
AT (1) | ATE283349T1 (da) |
AU (1) | AU7634400A (da) |
CA (1) | CA2386506C (da) |
DE (2) | DE20023640U1 (da) |
DK (1) | DK1282690T3 (da) |
ES (1) | ES2230157T3 (da) |
PT (1) | PT1282690E (da) |
WO (1) | WO2001025402A1 (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7482114B2 (en) | 1999-10-06 | 2009-01-27 | Tigenix N.V. | In vivo assay and molecular markers for testing the phenotypic stability of cell populations, and selected cell populations for autologous transplantation |
PT1218037E (pt) | 1999-10-06 | 2005-05-31 | Tigenix Nv | Ensaios in vitro e marcadores moleculares para testar a estabilidade fenotipica de populacoes de celulas, e populacoes de celulas seleccionadas para transplantacao autologa |
AU2002309330A1 (en) * | 2001-05-17 | 2002-11-25 | Isotis N.V. | Isolation method of mesenchymal cells |
US7375077B2 (en) | 2003-09-19 | 2008-05-20 | The Board Of Trustees Of The University Of Illinois | In vivo synthesis of connective tissues |
EP1576957A1 (en) | 2004-03-18 | 2005-09-21 | Universiteit Twente | Tissue repair using pluripotent cells |
EP2004806A2 (en) | 2006-03-20 | 2008-12-24 | Tigenix N.V. | Methods to maintain, improve and restore the cartilage phenotype of chondrocytes |
NZ576360A (en) | 2006-11-24 | 2011-07-29 | Tigenix Nv | Marker genes for use in the identification of chondrocyte phenotypic stability and in the screening of factors influencing cartilage production |
EA018959B1 (ru) | 2008-09-22 | 2013-12-30 | Аркариос Б.В. | Карбоксиэтилированные полисульфаты циклодекстрина, подходящие для применения в качестве лекарственных средств |
ES2370794B1 (es) * | 2010-05-25 | 2012-10-31 | Servicio Andaluz De Salud | Biomarcador de células cartilaginosas humanas. |
EP2625264B1 (en) | 2010-10-08 | 2022-12-07 | Terumo BCT, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
US20160090569A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled Feed |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
EP3464565A4 (en) | 2016-05-25 | 2020-01-01 | Terumo BCT, Inc. | CELL EXPANSION |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
US11629332B2 (en) | 2017-03-31 | 2023-04-18 | Terumo Bct, Inc. | Cell expansion |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
WO2019118768A1 (en) * | 2017-12-13 | 2019-06-20 | Rita Perlingeiro | Enhanced differentiation and maturation of pluripotent stem cell-derived myogenic cells |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5904717A (en) * | 1986-01-28 | 1999-05-18 | Thm Biomedical, Inc. | Method and device for reconstruction of articular cartilage |
US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5197985A (en) | 1990-11-16 | 1993-03-30 | Caplan Arnold I | Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells |
US5226914A (en) | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
US5733542A (en) | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
US5811094A (en) * | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
US6010696A (en) | 1990-11-16 | 2000-01-04 | Osiris Therapeutics, Inc. | Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells |
US5837539A (en) | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
AU3692395A (en) * | 1994-07-29 | 1996-03-04 | United States Of America, As Represented By The Secretary Of Agriculture, The | Saccharomyces treatment to diminish campylobacter and salmonella populations in poultry |
US5972703A (en) * | 1994-08-12 | 1999-10-26 | The Regents Of The University Of Michigan | Bone precursor cells: compositions and methods |
CA2199377A1 (en) * | 1994-09-09 | 1996-03-14 | Emma E. Moore | Preparation of immortalized cells |
US5683906A (en) | 1994-09-09 | 1997-11-04 | Zymogenetics, Inc. | Preparation of immortalized cells |
US5648219A (en) | 1995-06-07 | 1997-07-15 | Zymogenetics, Inc. | Immortalized dendritic cells |
US5830682A (en) | 1994-09-09 | 1998-11-03 | Zymogenetics | Preparation of immortalized cells |
DK0836380T3 (da) * | 1995-06-12 | 2002-04-22 | Yeda Res & Dev | FGF9 som en specifik ligand for FGFR3 |
WO1997007200A1 (en) * | 1995-08-16 | 1997-02-27 | The Board Of Trustees Of The Leland Stanford Junior University | Adult oligodendrocyte precursor cell compositions and methods |
EP0877795A4 (en) * | 1996-01-16 | 2003-03-05 | Depuy Orthopaedics Inc | INSULATION OF PROCUREMENT CELLS FROM HEMATOPOIETIC AND NON-HEMATOPOIETIC TISSUES AND THEIR USE |
US6200606B1 (en) * | 1996-01-16 | 2001-03-13 | Depuy Orthopaedics, Inc. | Isolation of precursor cells from hematopoietic and nonhematopoietic tissues and their use in vivo bone and cartilage regeneration |
US5919702A (en) | 1996-10-23 | 1999-07-06 | Advanced Tissue Science, Inc. | Production of cartilage tissue using cells isolated from Wharton's jelly |
AU6144498A (en) * | 1997-02-06 | 1998-08-26 | Osiris Therapeutics, Inc. | P21cip1 or p27kip1 effects on the regulation of differentiation of human mesenchymal stem cells |
WO1998059035A2 (en) | 1997-06-25 | 1998-12-30 | The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services, National Institutes Of Health | Serum-free cell growth medium |
US6235527B1 (en) * | 1997-11-29 | 2001-05-22 | University Of Utah Research Foundation | Lineage restricted glial precursors from the central nervous system |
-
2000
- 2000-10-06 WO PCT/BE2000/000120 patent/WO2001025402A1/en active IP Right Grant
- 2000-10-06 AU AU76344/00A patent/AU7634400A/en not_active Abandoned
- 2000-10-06 DE DE20023640U patent/DE20023640U1/de not_active Expired - Lifetime
- 2000-10-06 PT PT00965662T patent/PT1282690E/pt unknown
- 2000-10-06 DK DK00965662T patent/DK1282690T3/da active
- 2000-10-06 DE DE60016288T patent/DE60016288T2/de not_active Expired - Lifetime
- 2000-10-06 EP EP00965662A patent/EP1282690B9/en not_active Expired - Lifetime
- 2000-10-06 AT AT00965662T patent/ATE283349T1/de active
- 2000-10-06 ES ES00965662T patent/ES2230157T3/es not_active Expired - Lifetime
- 2000-10-06 CA CA2386506A patent/CA2386506C/en not_active Expired - Lifetime
-
2008
- 2008-07-18 US US12/176,256 patent/US7863045B2/en not_active Expired - Fee Related
-
2011
- 2011-01-03 US US12/983,658 patent/US20110158960A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE283349T1 (de) | 2004-12-15 |
US20110158960A1 (en) | 2011-06-30 |
CA2386506A1 (en) | 2001-04-12 |
EP1282690B1 (en) | 2004-11-24 |
AU7634400A (en) | 2001-05-10 |
DE60016288D1 (de) | 2004-12-30 |
EP1282690B9 (en) | 2005-03-02 |
PT1282690E (pt) | 2005-02-28 |
EP1282690A1 (en) | 2003-02-12 |
US20090123927A1 (en) | 2009-05-14 |
CA2386506C (en) | 2012-02-21 |
DE20023640U1 (de) | 2005-06-23 |
ES2230157T3 (es) | 2005-05-01 |
US7863045B2 (en) | 2011-01-04 |
WO2001025402A1 (en) | 2001-04-12 |
DE60016288T2 (de) | 2005-12-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1282690T3 (da) | Isolation af precursorceller og anvendelse deraf til vævsreparation | |
Phillips et al. | Directed differentiation of human induced pluripotent stem cells toward bone and cartilage: in vitro versus in vivo assays | |
CN1934245B (zh) | 多能干细胞的增殖方法 | |
WO2005103716A3 (en) | Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts | |
Tsuchiya et al. | Osteogenic differentiation capacity of porcine dental follicle progenitor cells | |
Harkness et al. | Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential | |
WO2003022988A3 (en) | Adipose-derived stem cells and lattices | |
Delannet et al. | Transforming growth factor-β control of cell-substratum adhesion during avian neural crest cell emigration in vitro | |
AR020735A1 (es) | Un procedimiento para la obtencion de un polipeptido glucosilado a partir de celulas eucarioticas | |
CA2345397A1 (en) | Trophoblast cell preparations | |
WO2006127809A3 (en) | Methods for expansion and analysis of cultured hematopoietic stem cells | |
Koudan et al. | Multiparametric analysis of tissue spheroids fabricated from different types of cells | |
KR102263824B1 (ko) | 심장 세포 배양 재료 | |
Fleming et al. | Bioengineered human skeletal muscle capable of functional regeneration | |
CN110128546A (zh) | 一种用于rna示踪的融合蛋白及其应用 | |
ATE513851T1 (de) | Menschliches gen zur fruchtbarkeit entscheidend | |
Hadjiargyrou et al. | The E11 osteoblastic lineage marker is differentially expressed during fracture healing | |
Bissiere et al. | Cell fate decisions during preimplantation mammalian development | |
Ono et al. | Developmental biology of musculoskeletal tissues for tissue engineers | |
GB2425312A (en) | Method for cell surface display of target proteins using fadl of e coli | |
ATE508183T1 (de) | Sekretierte proteine für zelldifferenzierungsmarker | |
Sen et al. | Very late antigen-5 facilitates stromal progenitor cell differentiation into myofibroblast | |
Sadeghi et al. | Co-culture of mouse blastocysts on a human recellularized endometrial scaffold: an in vitro model for future implantation studies | |
Levi et al. | An antibody against a sequence of human topoisomerase II gives different immunofluorescence patterns in quiescent and proliferating nuclei of Pisum sativum L. | |
CN101422631B (zh) | PLGA材料在ADSCs为基础的组织工程肝单元构建中的应用 |