DK1280890T3 - Mutante stammer, der er i stand til at producere kemisk differentierede proteiner ved inkorporering af ikke-traditionelle aminosyrer - Google Patents

Mutante stammer, der er i stand til at producere kemisk differentierede proteiner ved inkorporering af ikke-traditionelle aminosyrer

Info

Publication number
DK1280890T3
DK1280890T3 DK01929739T DK01929739T DK1280890T3 DK 1280890 T3 DK1280890 T3 DK 1280890T3 DK 01929739 T DK01929739 T DK 01929739T DK 01929739 T DK01929739 T DK 01929739T DK 1280890 T3 DK1280890 T3 DK 1280890T3
Authority
DK
Denmark
Prior art keywords
proteins
incorporation
amino acids
mutant strains
strains capable
Prior art date
Application number
DK01929739T
Other languages
English (en)
Inventor
Henning Mootz
Philippe Marliere
Volker Doring
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of DK1280890T3 publication Critical patent/DK1280890T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
DK01929739T 2000-04-28 2001-04-27 Mutante stammer, der er i stand til at producere kemisk differentierede proteiner ved inkorporering af ikke-traditionelle aminosyrer DK1280890T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0005547A FR2808284B1 (fr) 2000-04-28 2000-04-28 Souches mutantes capables de produire des proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels
PCT/FR2001/001306 WO2001083718A1 (fr) 2000-04-28 2001-04-27 Souches mutantes capables de produire des proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels

Publications (1)

Publication Number Publication Date
DK1280890T3 true DK1280890T3 (da) 2007-03-12

Family

ID=8849772

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01929739T DK1280890T3 (da) 2000-04-28 2001-04-27 Mutante stammer, der er i stand til at producere kemisk differentierede proteiner ved inkorporering af ikke-traditionelle aminosyrer

Country Status (15)

Country Link
US (1) US20040014942A1 (da)
EP (1) EP1280890B1 (da)
JP (1) JP2004518404A (da)
AT (1) ATE350469T1 (da)
AU (2) AU5643301A (da)
CA (1) CA2407595A1 (da)
CY (1) CY1105936T1 (da)
DE (1) DE60125754T2 (da)
DK (1) DK1280890T3 (da)
ES (1) ES2273836T3 (da)
FR (1) FR2808284B1 (da)
MX (1) MXPA02010462A (da)
NZ (1) NZ522805A (da)
PT (1) PT1280890E (da)
WO (1) WO2001083718A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344836T1 (de) 2001-04-19 2006-11-15 Pasteur Institut Methode für die erweiterung der chemischen zusammensetzung von proteinen produziert in vivo unter verwendung von mutierten aminoacyl-trna- synthetasen ohne korrekturfunktion
EP1251175B1 (en) * 2001-04-19 2006-11-08 Institut Pasteur Method for diversifying the chemical composition of protein produced in vivo by genetically disabling the editing function of their aminoacyl tRNA synthetases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2785291B1 (fr) * 1998-10-28 2003-03-07 Pasteur Institut Procede de production in vivo de proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels

Also Published As

Publication number Publication date
FR2808284A1 (fr) 2001-11-02
JP2004518404A (ja) 2004-06-24
DE60125754D1 (de) 2007-02-15
MXPA02010462A (es) 2003-05-23
AU2001256433C1 (en) 2001-11-12
DE60125754T2 (de) 2007-10-31
CA2407595A1 (fr) 2001-11-08
EP1280890A1 (fr) 2003-02-05
CY1105936T1 (el) 2011-04-06
EP1280890B1 (fr) 2007-01-03
ES2273836T3 (es) 2007-05-16
AU2001256433B2 (en) 2006-07-06
WO2001083718A1 (fr) 2001-11-08
PT1280890E (pt) 2007-02-28
AU5643301A (en) 2001-11-12
FR2808284B1 (fr) 2004-11-19
US20040014942A1 (en) 2004-01-22
ATE350469T1 (de) 2007-01-15
NZ522805A (en) 2004-09-24

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