DE60125754D1 - Mutantenstämme geeignet zur herstellung von chemisch unterschiedlichen proteinen, die nicht-konventionelle aminosäuren enthalten - Google Patents

Mutantenstämme geeignet zur herstellung von chemisch unterschiedlichen proteinen, die nicht-konventionelle aminosäuren enthalten

Info

Publication number
DE60125754D1
DE60125754D1 DE60125754T DE60125754T DE60125754D1 DE 60125754 D1 DE60125754 D1 DE 60125754D1 DE 60125754 T DE60125754 T DE 60125754T DE 60125754 T DE60125754 T DE 60125754T DE 60125754 D1 DE60125754 D1 DE 60125754D1
Authority
DE
Germany
Prior art keywords
mutant
manufacture
amino acids
conventional amino
containing non
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60125754T
Other languages
English (en)
Other versions
DE60125754T2 (de
Inventor
Philippe Marliere
Volker Doring
Henning Mootz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Publication of DE60125754D1 publication Critical patent/DE60125754D1/de
Application granted granted Critical
Publication of DE60125754T2 publication Critical patent/DE60125754T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60125754T 2000-04-28 2001-04-27 Mutantenstämme geeignet zur herstellung von chemisch unterschiedlichen proteinen, die nicht-konventionelle aminosäuren enthalten Expired - Lifetime DE60125754T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0005547 2000-04-28
FR0005547A FR2808284B1 (fr) 2000-04-28 2000-04-28 Souches mutantes capables de produire des proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels
PCT/FR2001/001306 WO2001083718A1 (fr) 2000-04-28 2001-04-27 Souches mutantes capables de produire des proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels

Publications (2)

Publication Number Publication Date
DE60125754D1 true DE60125754D1 (de) 2007-02-15
DE60125754T2 DE60125754T2 (de) 2007-10-31

Family

ID=8849772

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60125754T Expired - Lifetime DE60125754T2 (de) 2000-04-28 2001-04-27 Mutantenstämme geeignet zur herstellung von chemisch unterschiedlichen proteinen, die nicht-konventionelle aminosäuren enthalten

Country Status (15)

Country Link
US (1) US20040014942A1 (de)
EP (1) EP1280890B1 (de)
JP (1) JP2004518404A (de)
AT (1) ATE350469T1 (de)
AU (2) AU2001256433B2 (de)
CA (1) CA2407595A1 (de)
CY (1) CY1105936T1 (de)
DE (1) DE60125754T2 (de)
DK (1) DK1280890T3 (de)
ES (1) ES2273836T3 (de)
FR (1) FR2808284B1 (de)
MX (1) MXPA02010462A (de)
NZ (1) NZ522805A (de)
PT (1) PT1280890E (de)
WO (1) WO2001083718A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344836T1 (de) 2001-04-19 2006-11-15 Pasteur Institut Methode für die erweiterung der chemischen zusammensetzung von proteinen produziert in vivo unter verwendung von mutierten aminoacyl-trna- synthetasen ohne korrekturfunktion
EP1251175B1 (de) * 2001-04-19 2006-11-08 Institut Pasteur Methode für die Erweiterung der chemischen Zusammensetzung von Proteinen produziert in vivo unter Verwendung von mutierten Aminoacyl-tRNA-Synthetasen ohne Korrekturfunktion

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2785291B1 (fr) * 1998-10-28 2003-03-07 Pasteur Institut Procede de production in vivo de proteines chimiquement diversifiees par incorporation d'acides amines non conventionnels

Also Published As

Publication number Publication date
US20040014942A1 (en) 2004-01-22
DK1280890T3 (da) 2007-03-12
AU5643301A (en) 2001-11-12
WO2001083718A1 (fr) 2001-11-08
NZ522805A (en) 2004-09-24
CY1105936T1 (el) 2011-04-06
FR2808284B1 (fr) 2004-11-19
EP1280890A1 (de) 2003-02-05
ATE350469T1 (de) 2007-01-15
CA2407595A1 (fr) 2001-11-08
DE60125754T2 (de) 2007-10-31
ES2273836T3 (es) 2007-05-16
MXPA02010462A (es) 2003-05-23
AU2001256433B2 (en) 2006-07-06
AU2001256433C1 (en) 2001-11-12
JP2004518404A (ja) 2004-06-24
EP1280890B1 (de) 2007-01-03
FR2808284A1 (fr) 2001-11-02
PT1280890E (pt) 2007-02-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: DF-MP, 80333 MUENCHEN