DK127887A - Interleukin-1beta-derivater og medikamenter indeholdende saadanne derivater - Google Patents

Interleukin-1beta-derivater og medikamenter indeholdende saadanne derivater

Info

Publication number
DK127887A
DK127887A DK127887A DK127887A DK127887A DK 127887 A DK127887 A DK 127887A DK 127887 A DK127887 A DK 127887A DK 127887 A DK127887 A DK 127887A DK 127887 A DK127887 A DK 127887A
Authority
DK
Denmark
Prior art keywords
derivatives
1beta
interleukin
medicines containing
medicines
Prior art date
Application number
DK127887A
Other languages
English (en)
Other versions
DK127887D0 (da
DK171648B1 (da
Inventor
Satoru Nakai
Mayumi Kaneta
Yoshikazu Kikumoto
Yeong-Man Hong
Kazuyoshi Kawai
Setsuko Takegata
Kiyoshi Ishii
Yasuo Yanagihara
Yoshikatsu Hirai
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of DK127887D0 publication Critical patent/DK127887D0/da
Publication of DK127887A publication Critical patent/DK127887A/da
Application granted granted Critical
Publication of DK171648B1 publication Critical patent/DK171648B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK127887A 1986-03-14 1987-03-12 Polypeptid, der er et interleukin-1beta-derivat, gen, der koder for polypeptidet, vektor indeholdende genet, mikroorganisme indeholdende vektoren, og lægemidel indeholdende polypeptidet DK171648B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP5788586 1986-03-14
JP5788586 1986-03-14
JP14583086 1986-06-20
JP14583086 1986-06-20
JP16118486 1986-07-09
JP16118486 1986-07-09
JP20032486 1986-08-27
JP20032486 1986-08-27

Publications (3)

Publication Number Publication Date
DK127887D0 DK127887D0 (da) 1987-03-12
DK127887A true DK127887A (da) 1987-09-15
DK171648B1 DK171648B1 (da) 1997-03-03

Family

ID=27463573

Family Applications (1)

Application Number Title Priority Date Filing Date
DK127887A DK171648B1 (da) 1986-03-14 1987-03-12 Polypeptid, der er et interleukin-1beta-derivat, gen, der koder for polypeptidet, vektor indeholdende genet, mikroorganisme indeholdende vektoren, og lægemidel indeholdende polypeptidet

Country Status (5)

Country Link
EP (2) EP0569042A1 (da)
JP (1) JP2591615B2 (da)
DE (1) DE3751593T2 (da)
DK (1) DK171648B1 (da)
ES (1) ES2009215A6 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047505A (en) * 1987-01-27 1991-09-10 Du Pont Merck Pharmaceutical Company High level expression in E. coli of soluble mature HIL-1beta and derivatives with altered biological activity
US4904584A (en) * 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
JP2698976B2 (ja) * 1988-02-03 1998-01-19 大日本製薬株式会社 新規ポリペプチド及びそれをコードするｄｎａ
KR960008010B1 (ko) * 1988-07-29 1996-06-19 오오쓰까세이야꾸 가부시끼가이샤 IL-1α 유도체 및 혈소판 감소증 치료 약제
JP2554528B2 (ja) * 1988-09-19 1996-11-13 大塚製薬株式会社 副腎皮質刺激ホルモン分泌能検査薬
WO1990006127A1 (en) * 1988-12-06 1990-06-14 Otsuka Pharmaceutical Co., Ltd. STABILIZED COMPOSITION OF INTERLEUKIN-1$g(b)
US5039790A (en) * 1989-01-11 1991-08-13 Monsanto Company Bioactive fragment of interleukin-1-B that has antagonistic activity
DK0460052T3 (da) * 1989-02-27 1999-03-08 New England Medical Center Inc Inhibitorer af IL-1's biologiske aktivitet
US5723117A (en) * 1990-08-10 1998-03-03 Otsuka Pharmaceutical Co., Ltd. Use of interleukin-1 (IL-1) to inhibit development of hepatitis
JP2678689B2 (ja) * 1990-08-10 1997-11-17 大塚製薬株式会社 肝炎予防・治療剤
EP0495131B1 (en) * 1990-08-10 1997-05-14 Otsuka Pharmaceutical Co., Ltd. Agent for preventing and treating hepatitis
FR2667601A1 (fr) * 1990-10-05 1992-04-10 Rhone Poulenc Sante Polypeptides derives de l'interleukine-1 beta, procede de preparation et utilisation, notamment dans le cadre des pathologies osteoarticulaires.
AU1270592A (en) * 1991-02-05 1992-09-07 University Of Maryland Modified interleukin-1beta
SE9201966D0 (sv) * 1992-06-25 1992-06-25 Trion Forskning & Utveckling Interleukin-1beta deletion mutant
GB9916630D0 (en) * 1999-07-16 1999-09-15 Univ Manchester Molecules derived from interleukins
DE60040740D1 (de) * 1999-12-03 2008-12-18 Celltech Chiroscience Ltd VERWENDUNG OF INTERLEUkIN-1 MUTEIN ALS IMPFSTOFFADJUVANS
DE10141749A1 (de) * 2000-08-29 2002-03-14 Max Delbrueck Centrum Mittel zur Beeinflussung der Angiogenese
CN1960744A (zh) * 2004-02-27 2007-05-09 瓦克斯咨询公司 肽IL1β和TNFα以及应用其治疗的方法
UA99990C2 (uk) * 2009-03-17 2012-10-25 Общєство С Огранічєнной Отвєтствєнностью "Сєнгара" Інтерлейкін-1 бета в косметичних композиціях і способи його використання

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816436A (en) * 1986-10-29 1989-03-28 Immunex Corporation Anti-arthritic use of interleukin-1 proteins

Also Published As

Publication number Publication date
EP0237967A3 (en) 1990-03-28
DK127887D0 (da) 1987-03-12
EP0237967B1 (en) 1995-11-15
DE3751593T2 (de) 1996-03-28
EP0569042A1 (en) 1993-11-10
DE3751593D1 (de) 1995-12-21
DK171648B1 (da) 1997-03-03
EP0237967A2 (en) 1987-09-23
JPS63152398A (ja) 1988-06-24
JP2591615B2 (ja) 1997-03-19
ES2009215A6 (es) 1989-09-16

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed