DK127428B - Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on. - Google Patents

Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on.

Info

Publication number
DK127428B
DK127428B DK60370A DK60370A DK127428B DK 127428 B DK127428 B DK 127428B DK 60370 A DK60370 A DK 60370A DK 60370 A DK60370 A DK 60370A DK 127428 B DK127428 B DK 127428B
Authority
DK
Denmark
Prior art keywords
benzodiazepin
dihydro
chloro
phenyl
methyl
Prior art date
Application number
DK60370A
Other languages
English (en)
Inventor
F Kajfez
N Blazevic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK127428B publication Critical patent/DK127428B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK60370A 1969-10-16 1970-02-09 Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on. DK127428B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1549969A CH537393A (de) 1969-10-16 1969-10-16 Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten

Publications (1)

Publication Number Publication Date
DK127428B true DK127428B (da) 1973-11-05

Family

ID=4409581

Family Applications (1)

Application Number Title Priority Date Filing Date
DK60370A DK127428B (da) 1969-10-16 1970-02-09 Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on.

Country Status (7)

Country Link
JP (1) JPS5313637B1 (da)
CH (1) CH537393A (da)
DK (1) DK127428B (da)
FI (1) FI49831C (da)
NL (1) NL159973C (da)
NO (1) NO125095B (da)
SE (1) SE367632B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK155326B (da) * 1972-08-21 1989-03-28 Hoffmann La Roche Fremgangsmaade til fremstilling af 1,4-benzodiazepin-2-on-derivater

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4155904A (en) * 1973-02-08 1979-05-22 Schering Corporation Process for the preparation of 1,4-benzo-diazepines and 1,4-benzodiazepinones
US3996209A (en) * 1973-05-14 1976-12-07 Hoffmann-La Roche Inc. Process for preparing benzodiazepines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK155326B (da) * 1972-08-21 1989-03-28 Hoffmann La Roche Fremgangsmaade til fremstilling af 1,4-benzodiazepin-2-on-derivater

Also Published As

Publication number Publication date
SE367632B (da) 1974-06-04
NL159973C (nl) 1979-09-17
NL7001765A (da) 1971-04-20
DE2016084A1 (de) 1971-04-29
JPS5313637B1 (da) 1978-05-11
FI49831C (fi) 1975-10-10
CH537393A (de) 1973-05-31
DE2016084B2 (de) 1976-06-16
FI49831B (da) 1975-06-30
NO125095B (da) 1972-07-17

Similar Documents

Publication Publication Date Title
DK140697B (da) Fremgangsmåde til fremstilling af 2-amino-4-hydroxy-6-hydroxymethyl-7,7-dimethyl-7,8-dihydropteridin.
DK131904B (da) Analogifremgangsmåde til fremstilling af 1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepinderivater.
DK120492B (da) Fremgangsmåde til fremstilling af 3-acylamido-5-aryl-1,3-dihydro-2H-1,4-benzodiazepin-2-on-forbindelser.
DK127428B (da) Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on.
DK120901B (da) Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on.
DK137754B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK112527B (da) Fremgangsmåde til fremstilling af 1,3,4,5-tetrahydro-1,4-benzodiazepinderivater.
DK127784B (da) Fremgangsmåde til fremstilling af 1-aryl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-oner.
DK117499B (da) Fremgangsmåde til fremstilling af 1,3-dihydro-3-hydroxy-1,4-benzodiazepin-2-oner.
FI49168C (fi) Menetelmä 7-halogeeni-1-alkyyli-5-fenyyli-2,3-dihydro-1H-1,4-bentso-di atsepiinien valmistamiseksi.
DK138370B (da) Fremgangsmåde til fremstilling af 1-methyl-7-halogen-2,3-dihyro-5-phenyl-1,4-benzodiazepiner.
DK137573C (da) Fremgangsmaade til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-on
DK118953B (da) Fremgangsmåde til fremstilling af 1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-on-derivater.
DK127115B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK115921B (da) Fremgangsmåde til fremstilling af 3-acyloxy-5-aryl-1,3-dihydro-2H-1,4-benzodiazepin-2-oner.
DK137855B (da) Analogifremgangsmåde til fremstilling af optisk aktive 1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-on-derivater.
DK134433B (da) Fremgangsmåde til fremstilling af 7-chlor-1-methyl-5-phenyl-2,3-dihyro-1H-1,4-benzodiazepin-2-on.
DK118086B (da) Fremgangsmåde til fremstilling af 3-hydroxy-1,4-benzodiazepin-2-oner.
DK128777B (da) Fremgangsmåde til fremstilling af 3β-alkanoyloxy-6-halogen-pregna-4,6-dien-20-oner.
DK140282B (da) Analogifremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK115998B (da) Fremgangsmåde til fremstilling af 3H-1,4-benzodiazepin-2-on-forbindelser.
DK133779B (da) Analogifremgangsmåde til fremstilling af 3-amino-5-aryl-1,3-dihydro-2H-1,4-benzodiazepin-2-on-forbindelser.
DK126190B (da) Fremgangsmåde til fremstilling af 4-chlor-14β-hydroxy-carda-4,20(22)-dienolider.
FI50123C (fi) Menetelmä 1-metyyli-2,3-dihydro-1H-1,4-bentsodiatsepiinien tai 1-metyy li-1,3-dihydro-2H-1,4-bentsodiatsepiini-2-onien valmistamiseksi.
DK136422B (da) Fremgangsmåde til rensning af 1,4-benzodiazepin-2-onderivater.