NL159973C - Werkwijze voor de bereiding van 7-chloor-1,3-dihydro-1- -methyl-5-fenyl-2h-1,4-benzodiazepin-2-on. - Google Patents

Werkwijze voor de bereiding van 7-chloor-1,3-dihydro-1- -methyl-5-fenyl-2h-1,4-benzodiazepin-2-on.

Info

Publication number
NL159973C
NL159973C NL7001765A NL7001765A NL159973C NL 159973 C NL159973 C NL 159973C NL 7001765 A NL7001765 A NL 7001765A NL 7001765 A NL7001765 A NL 7001765A NL 159973 C NL159973 C NL 159973C
Authority
NL
Netherlands
Prior art keywords
benzodiazepin
dihydro
chloro
phenyl
methyl
Prior art date
Application number
NL7001765A
Other languages
English (en)
Dutch (nl)
Other versions
NL7001765A (da
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL7001765A publication Critical patent/NL7001765A/xx
Application granted granted Critical
Publication of NL159973C publication Critical patent/NL159973C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NL7001765A 1969-10-16 1970-02-06 Werkwijze voor de bereiding van 7-chloor-1,3-dihydro-1- -methyl-5-fenyl-2h-1,4-benzodiazepin-2-on. NL159973C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1549969A CH537393A (de) 1969-10-16 1969-10-16 Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten

Publications (2)

Publication Number Publication Date
NL7001765A NL7001765A (da) 1971-04-20
NL159973C true NL159973C (nl) 1979-09-17

Family

ID=4409581

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7001765A NL159973C (nl) 1969-10-16 1970-02-06 Werkwijze voor de bereiding van 7-chloor-1,3-dihydro-1- -methyl-5-fenyl-2h-1,4-benzodiazepin-2-on.

Country Status (7)

Country Link
JP (1) JPS5313637B1 (da)
CH (1) CH537393A (da)
DK (1) DK127428B (da)
FI (1) FI49831C (da)
NL (1) NL159973C (da)
NO (1) NO125095B (da)
SE (1) SE367632B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH578544A5 (da) * 1972-08-21 1976-08-13 Hoffmann La Roche
US4155904A (en) * 1973-02-08 1979-05-22 Schering Corporation Process for the preparation of 1,4-benzo-diazepines and 1,4-benzodiazepinones
US3996209A (en) * 1973-05-14 1976-12-07 Hoffmann-La Roche Inc. Process for preparing benzodiazepines

Also Published As

Publication number Publication date
FI49831C (fi) 1975-10-10
DE2016084B2 (de) 1976-06-16
FI49831B (da) 1975-06-30
CH537393A (de) 1973-05-31
SE367632B (da) 1974-06-04
DE2016084A1 (de) 1971-04-29
NO125095B (da) 1972-07-17
NL7001765A (da) 1971-04-20
DK127428B (da) 1973-11-05
JPS5313637B1 (da) 1978-05-11

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: HOFFMANN