CH537393A - Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten - Google Patents

Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten

Info

Publication number
CH537393A
CH537393A CH1549969A CH1549969A CH537393A CH 537393 A CH537393 A CH 537393A CH 1549969 A CH1549969 A CH 1549969A CH 1549969 A CH1549969 A CH 1549969A CH 537393 A CH537393 A CH 537393A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH1549969A
Other languages
German (de)
English (en)
Inventor
Kajfez Franjo Ing Dr
Blazevic Nikola
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1549969A priority Critical patent/CH537393A/de
Priority to NL7001765A priority patent/NL159973C/xx
Priority to DK60370A priority patent/DK127428B/da
Priority to FI37370A priority patent/FI49831C/fi
Priority to NO48670A priority patent/NO125095B/no
Priority to JP1337770A priority patent/JPS5313637B1/ja
Priority to SE242070A priority patent/SE367632B/xx
Priority to DE19702016084 priority patent/DE2016084C3/de
Publication of CH537393A publication Critical patent/CH537393A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/30—Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1549969A 1969-10-16 1969-10-16 Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten CH537393A (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CH1549969A CH537393A (de) 1969-10-16 1969-10-16 Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten
NL7001765A NL159973C (nl) 1969-10-16 1970-02-06 Werkwijze voor de bereiding van 7-chloor-1,3-dihydro-1- -methyl-5-fenyl-2h-1,4-benzodiazepin-2-on.
DK60370A DK127428B (da) 1969-10-16 1970-02-09 Fremgangsmåde til fremstilling af 7-chlor-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-on.
FI37370A FI49831C (fi) 1969-10-16 1970-02-11 Menetelmä 7-kloori-1,3-dihydro-1-metyyli-5-fenyyli-2H-1,4-dibentsodiat sepiini-2-onin valmistamiseksi.
NO48670A NO125095B (da) 1969-10-16 1970-02-12
JP1337770A JPS5313637B1 (da) 1969-10-16 1970-02-16
SE242070A SE367632B (da) 1969-10-16 1970-02-25
DE19702016084 DE2016084C3 (de) 1969-10-16 1970-04-03 Verfahren zur Herstellung von 7-Chlor-1,3-dihydro-1 -methyl-5-phenyl-2H-1,4-benzodiazepin-2-on

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1549969A CH537393A (de) 1969-10-16 1969-10-16 Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten

Publications (1)

Publication Number Publication Date
CH537393A true CH537393A (de) 1973-05-31

Family

ID=4409581

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1549969A CH537393A (de) 1969-10-16 1969-10-16 Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten

Country Status (7)

Country Link
JP (1) JPS5313637B1 (da)
CH (1) CH537393A (da)
DK (1) DK127428B (da)
FI (1) FI49831C (da)
NL (1) NL159973C (da)
NO (1) NO125095B (da)
SE (1) SE367632B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH578544A5 (da) * 1972-08-21 1976-08-13 Hoffmann La Roche
US4155904A (en) * 1973-02-08 1979-05-22 Schering Corporation Process for the preparation of 1,4-benzo-diazepines and 1,4-benzodiazepinones
US3996209A (en) * 1973-05-14 1976-12-07 Hoffmann-La Roche Inc. Process for preparing benzodiazepines

Also Published As

Publication number Publication date
NL7001765A (da) 1971-04-20
DE2016084B2 (de) 1976-06-16
FI49831B (da) 1975-06-30
NO125095B (da) 1972-07-17
FI49831C (fi) 1975-10-10
DE2016084A1 (de) 1971-04-29
JPS5313637B1 (da) 1978-05-11
SE367632B (da) 1974-06-04
DK127428B (da) 1973-11-05
NL159973C (nl) 1979-09-17

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Legal Events

Date Code Title Description
PL Patent ceased