DK125244B - Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf. - Google Patents

Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf.

Info

Publication number
DK125244B
DK125244B DK314269AA DK314269A DK125244B DK 125244 B DK125244 B DK 125244B DK 314269A A DK314269A A DK 314269AA DK 314269 A DK314269 A DK 314269A DK 125244 B DK125244 B DK 125244B
Authority
DK
Denmark
Prior art keywords
prednisolone
prednisone
fluoro
esters
methyl
Prior art date
Application number
DK314269AA
Other languages
Danish (da)
English (en)
Inventor
K Irmscher
D Orth
Original Assignee
Merck Ag E
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681793318 external-priority patent/DE1793318C3/de
Application filed by Merck Ag E filed Critical Merck Ag E
Publication of DK125244B publication Critical patent/DK125244B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK314269AA 1968-08-31 1969-06-11 Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf. DK125244B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681793318 DE1793318C3 (de) 1968-08-31 Verfahren zur Herstellung von 9 a-Fluor-16methylen-prednisolon bzw. -prednison und 21-Estern derselben

Publications (1)

Publication Number Publication Date
DK125244B true DK125244B (da) 1973-01-22

Family

ID=5707659

Family Applications (1)

Application Number Title Priority Date Filing Date
DK314269AA DK125244B (da) 1968-08-31 1969-06-11 Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf.

Country Status (13)

Country Link
US (1) US3684800A (pt)
AT (1) AT310956B (pt)
BE (1) BE738086A (pt)
BR (1) BR6910529D0 (pt)
CH (1) CH521333A (pt)
CS (1) CS172308B2 (pt)
DK (1) DK125244B (pt)
ES (1) ES371022A1 (pt)
FR (1) FR2016708A1 (pt)
GB (1) GB1213118A (pt)
IL (1) IL32378A (pt)
NL (1) NL6908358A (pt)
SE (1) SE351846B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207235A (en) * 1979-01-12 1980-06-10 Syntex (U.S.A.) Inc. Selective epoxidation of steroidal bromohydrins
CN101125877B (zh) * 2007-09-10 2011-04-06 浙江仙琚制药股份有限公司 甲基泼尼松龙醋酸酯的制备方法
CN102061320B (zh) * 2010-12-02 2013-04-03 浙江仙琚制药股份有限公司 11α，17α-二羟基-雄甾-4-烯-3，20-二酮的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3321496A (en) * 1960-11-17 1967-05-23 Merck & Co Inc 16alpha-halo methyl-saturated steroids of the pregnane series
US3376294A (en) * 1961-04-26 1968-04-02 Pfizer & Co C 6-fluoro-16-methylene steroid compounds and process
DE1251758B (de) * 1965-03-23 1967-10-12 E Merck Aktiengesellschaft, Darmstadt Verfahien zur Herstellung von 6a, 9a-Difluor- 16 methylen 1 4 pregnadien 11/?, 17a d'ol 3 20 dion

Also Published As

Publication number Publication date
BE738086A (pt) 1970-03-02
AT310956B (de) 1973-10-25
BR6910529D0 (pt) 1973-03-13
CS172308B2 (pt) 1976-12-29
US3684800A (en) 1972-08-15
IL32378A0 (en) 1969-08-27
DE1793318A1 (de) 1972-03-02
DE1793318B2 (de) 1976-12-30
CH521333A (de) 1972-04-15
ES371022A1 (es) 1971-12-16
GB1213118A (en) 1970-11-18
NL6908358A (pt) 1970-03-03
FR2016708A1 (pt) 1970-05-08
IL32378A (en) 1972-10-29
SE351846B (pt) 1972-12-11

Similar Documents

Publication Publication Date Title
DK112949B (da) Fremgangsmåde til fremstilling af O-mycaminosyl-tylonolid eller dihydro-O-mycaminosyl-tylonolid.
DK129339B (da) Analogifremgangsmåde til fremstilling af N-aminophenylamidiner.
DK120489B (da) Analogifremgangsmåde til fremstilling af 17α-alkenyl- eller -alkynyl-11,13β-dialkylgon-4-en-3,17β-dioler eller estere deraf.
DK136218B (da) Analogifremgangsmåde til fremstilling af 3alfa-hydroxysteroider af pregnan- eller 19-norpregnanrækken.
DK134489B (da) Fremgangsmåde til fremstilling af alkyl-7-desoxy-7(S)-substituerede-alfa-thiolincosaminider.
DK126990B (da) Fremgangsmåde til fremstilling af cystin- eller desaminocystin-holdige peptider eller derivater deraf.
DK130467B (da) Fremgangsmåde til fremstilling af erythromycylaminer.
DK125244B (da) Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf.
DK127977B (da) Fremgangsmåde til fremstilling af 6α-methyl-19-nor-pregnener.
DK133682B (da) Analogifremgangsmåde til fremstilling af 3alfa-hydroxy-5alfa-pregn-1-en-20-oner eller 3alfa-hydroxy-17beta-alkoxykarbonyl-5alfa-androst-1-ener.
DK126323B (da) Fremgangsmåde til fremstilling af 3β-hydroxy-5α-cardenolider eller -bufadienolider.
DK122882B (da) Fremgangsmåde til fremstilling af kawain eller methysticin.
DK129453B (da) Analogifremgangsmåde til fremstilling af 1-aminoisoquinoliner.
DK128205B (da) Fremgangsmåde til fremstilling af 1-aryloxy-2-propanoler.
DK131786B (da) Fremgangsmåde til fremstilling af delta4-3-oxo-1alfa-methylsteroider.
DK127107B (da) Fremgangsmåde til fremstilling af 17α-propadienyl-17β-hydroxy-steroider.
DK129836B (da) Analogifremgangsmåde til fremstilling af 21-fluor-3β-hydroxy-pregna-5,16-dien-20-on eller estere deraf.
DK129990B (da) Analogifremgangsmåde til fremstilling af 3-oxo-13β-alkyl-17α-methyl-20?-hydroxy-18,19-di-nor-pregna-4,9-diener eller estere deraf.
DK129040B (da) Fremgangsmåde til fremstilling af 9α-chlor-11β-hydroxysteroider af pregnanrækken.
DK131820B (da) Analogifremgangsmåde til fremstilling af 4-aminoquinazoliner eller 1-aminoisoquinoliner.
DK121165B (da) Fremgangsmåde til fremstilling af 1-aminoalkyl-1-arylindenar eller 3-aminoalkyl-3-arylindan-1-oler.
DK124751B (da) Fremgangsmåde til fremstilling af 9α-fluor-16-methylen-prednisolon eller -prednison eller 21-estere deraf.
DK127414B (da) Analogifremgangsmåde til fremstilling af phenylhydrazider.
DK127852B (da) Analogifremgangsmåde til fremstilling af 22-substituerede cardenolidrhamnosider.
DK130149B (da) Analogifremgangsmåde til fremstilling af 11β-alkoxy-13β-alkylgon-4-en-3-oner eller enolestere deraf.