DK1234025T3 - Humane enzymer fra metalloproteasefamilien - Google Patents

Humane enzymer fra metalloproteasefamilien

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Publication number
DK1234025T3
DK1234025T3 DK00981279T DK00981279T DK1234025T3 DK 1234025 T3 DK1234025 T3 DK 1234025T3 DK 00981279 T DK00981279 T DK 00981279T DK 00981279 T DK00981279 T DK 00981279T DK 1234025 T3 DK1234025 T3 DK 1234025T3
Authority
DK
Denmark
Prior art keywords
polypeptides
human enzymes
metalloprotease family
therapy
polynucleotides
Prior art date
Application number
DK00981279T
Other languages
Danish (da)
English (en)
Inventor
Willy Deleersnijder
Rico Wiegers
Michael Weske
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Application granted granted Critical
Publication of DK1234025T3 publication Critical patent/DK1234025T3/da

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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6497—Endothelin-converting enzyme (3.4.24.71)
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24071—Endothelin-converting enzyme 1 (3.4.24.71)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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    • G—PHYSICS
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    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
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    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
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    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Wood Science & Technology (AREA)
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  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
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DK00981279T 1999-11-19 2000-11-17 Humane enzymer fra metalloproteasefamilien DK1234025T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP99203862 1999-11-19
NL1013616 1999-11-19
NL1015356 2000-05-31
EP00201937 2000-05-31
PCT/EP2000/011532 WO2001036610A1 (en) 1999-11-19 2000-11-17 Human enzymes of the metalloprotease family

Publications (1)

Publication Number Publication Date
DK1234025T3 true DK1234025T3 (da) 2008-11-17

Family

ID=27440008

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00981279T DK1234025T3 (da) 1999-11-19 2000-11-17 Humane enzymer fra metalloproteasefamilien

Country Status (13)

Country Link
US (5) US6855532B2 (de)
EP (1) EP1234025B1 (de)
JP (1) JP2003514525A (de)
CN (1) CN1250717C (de)
AT (1) ATE406438T1 (de)
AU (1) AU784327B2 (de)
CA (1) CA2392076A1 (de)
DE (1) DE60040089D1 (de)
DK (1) DK1234025T3 (de)
ES (1) ES2310527T3 (de)
HK (1) HK1052026A1 (de)
IL (2) IL149416A0 (de)
WO (1) WO2001036610A1 (de)

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WO2001036610A1 (en) 2001-05-25
IL149416A0 (en) 2002-11-10
EP1234025B1 (de) 2008-08-27
US7083965B2 (en) 2006-08-01
US20040224356A1 (en) 2004-11-11
AU1858201A (en) 2001-05-30
EP1234025A1 (de) 2002-08-28
ES2310527T3 (es) 2009-01-16
CN1250717C (zh) 2006-04-12
IL149416A (en) 2009-02-11
US6855532B2 (en) 2005-02-15
AU784327B2 (en) 2006-03-09
HK1052026A1 (en) 2003-08-29
US7312321B2 (en) 2007-12-25
CA2392076A1 (en) 2001-05-25
US20080070259A1 (en) 2008-03-20
US20030180877A1 (en) 2003-09-25
JP2003514525A (ja) 2003-04-22
US7189525B2 (en) 2007-03-13
CN1399678A (zh) 2003-02-26
DE60040089D1 (de) 2008-10-09
US20060205018A1 (en) 2006-09-14
US20070148688A1 (en) 2007-06-28
ATE406438T1 (de) 2008-09-15

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