ATE406438T1 - Menschliches homolog aus der familie der metalloproteasen - Google Patents
Menschliches homolog aus der familie der metalloproteasenInfo
- Publication number
- ATE406438T1 ATE406438T1 AT00981279T AT00981279T ATE406438T1 AT E406438 T1 ATE406438 T1 AT E406438T1 AT 00981279 T AT00981279 T AT 00981279T AT 00981279 T AT00981279 T AT 00981279T AT E406438 T1 ATE406438 T1 AT E406438T1
- Authority
- AT
- Austria
- Prior art keywords
- metalloproteases
- family
- polypeptides
- human homologue
- therapy
- Prior art date
Links
- 102000005741 Metalloproteases Human genes 0.000 title 1
- 108010006035 Metalloproteases Proteins 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 101710204001 Zinc metalloprotease Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
- C12N9/6497—Endothelin-converting enzyme (3.4.24.71)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N2333/914—Hydrolases (3)
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- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Psychiatry (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99203862 | 1999-11-19 | ||
| NL1013616 | 1999-11-19 | ||
| EP00201937 | 2000-05-31 | ||
| NL1015356 | 2000-05-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406438T1 true ATE406438T1 (de) | 2008-09-15 |
Family
ID=27440008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00981279T ATE406438T1 (de) | 1999-11-19 | 2000-11-17 | Menschliches homolog aus der familie der metalloproteasen |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US6855532B2 (de) |
| EP (1) | EP1234025B1 (de) |
| JP (1) | JP2003514525A (de) |
| CN (1) | CN1250717C (de) |
| AT (1) | ATE406438T1 (de) |
| AU (1) | AU784327B2 (de) |
| CA (1) | CA2392076A1 (de) |
| DE (1) | DE60040089D1 (de) |
| DK (1) | DK1234025T3 (de) |
| ES (1) | ES2310527T3 (de) |
| IL (2) | IL149416A0 (de) |
| WO (1) | WO2001036610A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020086405A1 (en) * | 2000-09-25 | 2002-07-04 | Inmaculada Silos-Santiago | 56638, a novel human neprilysin protease and uses thereof |
| ES2310527T3 (es) | 1999-11-19 | 2009-01-16 | Solvay Pharmaceuticals B.V. | Enzimas humanas de la familia de las metaloproteasas. |
| US6991916B2 (en) * | 2000-07-14 | 2006-01-31 | Pfizer Inc. | Compounds for the treatment of sexual dysfunction |
| AU2003273540A1 (en) * | 2002-05-31 | 2003-12-19 | Cognosci, Inc. | Assays for measuring matrix metalloproteinase activities |
| US20040014131A1 (en) * | 2002-07-09 | 2004-01-22 | Pfizer Inc. | Assay methods |
| US7427611B2 (en) | 2003-09-26 | 2008-09-23 | Solvay Pharmaceuticals Gmbh | Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them |
| US7452875B2 (en) | 2003-09-26 | 2008-11-18 | Solvay Pharmaceuticals Gmbh | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them |
| US7262184B2 (en) | 2003-09-26 | 2007-08-28 | Solvay Pharmaceuticals Gmbh | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them |
| US8883144B2 (en) * | 2010-09-02 | 2014-11-11 | The Regents Of The University Of Colorado, A Body Corporate | Treatment of pulmonary vascular remodeling with neprilysin |
| US9861519B2 (en) | 2010-12-16 | 2018-01-09 | Scion Neurostim, Llc | Apparatus and methods for titrating caloric vestibular stimulation |
| WO2019035916A1 (en) | 2017-08-15 | 2019-02-21 | Northwestern University | DESIGN OF PROTEIN GLYCOSYLATION SITES BY RAPID EXPRESSION AND CHARACTERIZATION OF N-GLYCOSYLTRANSFERASES |
| US11725224B2 (en) | 2018-04-16 | 2023-08-15 | Northwestern University | Methods for co-activating in vitro non-standard amino acid (nsAA) incorporation and glycosylation in crude cell lysates |
| CN113490748A (zh) | 2019-02-25 | 2021-10-08 | 西北大学 | 来源于梭菌属提取物的无细胞蛋白质合成平台 |
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| IL88535A0 (en) * | 1987-12-04 | 1989-06-30 | Dana Farber Cancer Inst Inc | Common acute lymphoblastic leukemia antigen |
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| CA2100355A1 (en) * | 1991-02-04 | 1992-08-05 | Lynne H. Parker Botehlo | Endothelin converting enzyme |
| DE19681565D2 (de) * | 1996-07-22 | 1999-11-11 | Goehrig Anja | Bolzenschneider |
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| CA2260376A1 (en) | 1999-02-11 | 2000-08-11 | Universite De Montreal | New metalloproteases of the neprilysin family |
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| AUPP948299A0 (en) * | 1999-03-29 | 1999-04-22 | Taylor, Stephen Dennis | Adjustable mounting literature display system |
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| JP2004504812A (ja) | 2000-05-04 | 2004-02-19 | スージェン・インコーポレーテッド | 新規プロテアーゼ |
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| GB0130219D0 (en) | 2001-12-18 | 2002-02-06 | Pfizer Ltd | Compounds for the treatment of sexual dysfunction |
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| US7262184B2 (en) * | 2003-09-26 | 2007-08-28 | Solvay Pharmaceuticals Gmbh | Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them |
| AR046454A1 (es) * | 2003-11-18 | 2005-12-07 | Solvay Pharm Gmbh | Uso de un compuesto de acido benzazepin-n-acetico, composicion farmaceutica, y procedimiento para la produccion de dicha composicion farmaceutica |
-
2000
- 2000-11-17 ES ES00981279T patent/ES2310527T3/es not_active Expired - Lifetime
- 2000-11-17 AU AU18582/01A patent/AU784327B2/en not_active Ceased
- 2000-11-17 EP EP00981279A patent/EP1234025B1/de not_active Expired - Lifetime
- 2000-11-17 JP JP2001538489A patent/JP2003514525A/ja active Pending
- 2000-11-17 IL IL14941600A patent/IL149416A0/xx active IP Right Grant
- 2000-11-17 WO PCT/EP2000/011532 patent/WO2001036610A1/en not_active Ceased
- 2000-11-17 AT AT00981279T patent/ATE406438T1/de active
- 2000-11-17 CA CA002392076A patent/CA2392076A1/en not_active Abandoned
- 2000-11-17 DE DE60040089T patent/DE60040089D1/de not_active Expired - Lifetime
- 2000-11-17 CN CNB008158371A patent/CN1250717C/zh not_active Expired - Fee Related
- 2000-11-17 DK DK00981279T patent/DK1234025T3/da active
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2002
- 2002-04-30 IL IL149416A patent/IL149416A/en not_active IP Right Cessation
- 2002-05-20 US US10/147,928 patent/US6855532B2/en not_active Expired - Fee Related
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2004
- 2004-06-18 US US10/870,003 patent/US7083965B2/en not_active Expired - Lifetime
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2006
- 2006-05-15 US US11/433,388 patent/US7189525B2/en not_active Expired - Lifetime
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2007
- 2007-02-07 US US11/703,227 patent/US7312321B2/en not_active Expired - Lifetime
- 2007-10-15 US US11/872,568 patent/US20080070259A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7312321B2 (en) | 2007-12-25 |
| US20030180877A1 (en) | 2003-09-25 |
| CA2392076A1 (en) | 2001-05-25 |
| IL149416A (en) | 2009-02-11 |
| JP2003514525A (ja) | 2003-04-22 |
| US20070148688A1 (en) | 2007-06-28 |
| US7189525B2 (en) | 2007-03-13 |
| AU784327B2 (en) | 2006-03-09 |
| US20040224356A1 (en) | 2004-11-11 |
| DE60040089D1 (de) | 2008-10-09 |
| IL149416A0 (en) | 2002-11-10 |
| CN1399678A (zh) | 2003-02-26 |
| US20060205018A1 (en) | 2006-09-14 |
| DK1234025T3 (da) | 2008-11-17 |
| EP1234025A1 (de) | 2002-08-28 |
| HK1052026A1 (en) | 2003-08-29 |
| ES2310527T3 (es) | 2009-01-16 |
| US7083965B2 (en) | 2006-08-01 |
| CN1250717C (zh) | 2006-04-12 |
| US6855532B2 (en) | 2005-02-15 |
| WO2001036610A1 (en) | 2001-05-25 |
| US20080070259A1 (en) | 2008-03-20 |
| EP1234025B1 (de) | 2008-08-27 |
| AU1858201A (en) | 2001-05-30 |
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