DK1220848T3 - N-arylmethylthioanilid-forbindelser, som er nyttige til inhibition af replikationen af HIV - Google Patents

N-arylmethylthioanilid-forbindelser, som er nyttige til inhibition af replikationen af HIV

Info

Publication number
DK1220848T3
DK1220848T3 DK00963380T DK00963380T DK1220848T3 DK 1220848 T3 DK1220848 T3 DK 1220848T3 DK 00963380 T DK00963380 T DK 00963380T DK 00963380 T DK00963380 T DK 00963380T DK 1220848 T3 DK1220848 T3 DK 1220848T3
Authority
DK
Denmark
Prior art keywords
hiv
replication
arylmethylthioanilide
inhibiting
compounds useful
Prior art date
Application number
DK00963380T
Other languages
English (en)
Inventor
Walter Gerhard Brouwer
Ewa Maria Osika
Original Assignee
Uniroyal Chem Co Inc
Crompton Co Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniroyal Chem Co Inc, Crompton Co Cie filed Critical Uniroyal Chem Co Inc
Application granted granted Critical
Publication of DK1220848T3 publication Critical patent/DK1220848T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK00963380T 1999-09-17 2000-09-12 N-arylmethylthioanilid-forbindelser, som er nyttige til inhibition af replikationen af HIV DK1220848T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/398,649 US6143780A (en) 1999-09-17 1999-09-17 N-arylmethylthioanilide compounds useful for the inhibition of the replication of HIV
PCT/US2000/024986 WO2001019811A2 (en) 1999-09-17 2000-09-12 N-arymethylthioanilide compounds useful for the inhibition of the replication of hiv

Publications (1)

Publication Number Publication Date
DK1220848T3 true DK1220848T3 (da) 2004-03-29

Family

ID=23576222

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00963380T DK1220848T3 (da) 1999-09-17 2000-09-12 N-arylmethylthioanilid-forbindelser, som er nyttige til inhibition af replikationen af HIV

Country Status (8)

Country Link
US (1) US6143780A (da)
EP (1) EP1220848B1 (da)
AT (1) ATE254611T1 (da)
CA (1) CA2384134C (da)
DE (1) DE60006706T2 (da)
DK (1) DK1220848T3 (da)
ES (1) ES2211608T3 (da)
WO (1) WO2001019811A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1738797A (zh) 2002-11-19 2006-02-22 阿基里昂药品公司 取代的芳基硫脲和相关的化合物,病毒复制的抑制剂
DE102006052504A1 (de) * 2006-11-06 2008-05-08 Temper, Rupert Verfahren zum Herstellen eines Mittels gegen eine Infektionskrankheit
EP3048099A3 (en) * 2006-11-15 2016-09-21 YM BioSciences Australia Pty Ltd Inhibitors of kinase activity
DE102008015032A1 (de) * 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte Pyrazolamide und ihre Verwendung
DE102008015033A1 (de) * 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062878A1 (de) * 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte Furancarboxamide und ihre Verwendung
DE102008062863A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
EP2414830A2 (en) 2009-03-31 2012-02-08 Robert Zimmermann Modulation of adipose triglyceride lipase for prevention and treatment of cachexia, loss of weight and muscle atrophy and methods of screening therefor
US20220324835A1 (en) * 2018-01-26 2022-10-13 Nurix Therapeutics, Inc. Inhibitors of cbl-b and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696151A (en) * 1995-11-30 1997-12-09 Uniroyal Chemical Company, Inc. Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants
US6017947A (en) * 1999-09-17 2000-01-25 Brouwer; Walter Gerhard Heterocyclic carbodithioperoxyimidic compounds useful for the inhibition of the replication of HIV

Also Published As

Publication number Publication date
CA2384134C (en) 2011-01-18
EP1220848A2 (en) 2002-07-10
US6143780A (en) 2000-11-07
ATE254611T1 (de) 2003-12-15
EP1220848B1 (en) 2003-11-19
WO2001019811A3 (en) 2001-07-26
DE60006706D1 (de) 2003-12-24
WO2001019811A2 (en) 2001-03-22
DE60006706T2 (de) 2004-08-19
ES2211608T3 (es) 2004-07-16
CA2384134A1 (en) 2001-03-22

Similar Documents

Publication Publication Date Title
DK0769010T3 (da) 2-[1',2',4'-triazol-3'-yloxymethylen]-anilider og deres anvendelse som pesticider
NO953305L (no) Antranilsyrederivat
DK1109813T3 (da) Pyrroloindoler, pyridoindoler og azepinoindoler som 5-HT2C-agonister
WO2005095395A3 (en) Tetrahydronaphthyridine derivatives as cholesteryl ester transfer protein inhibitors
ATE361748T1 (de) 1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren
DE69319614D1 (de) 1,4-benzodiazepinderivate und ihre verwendung als cck-modulatoren
HUP0002894A2 (hu) Peszticid és fungicid hatású [2-(3-pirazolil- és 3-triazolil-oxi-metil)-fenil]-izoxazolonok, -triazolonok és - tetrazolonok, előállításuk, alkalmazásuk
DK1109809T3 (da) Pyrroloquinoliner til behandling af fedme
DK1220848T3 (da) N-arylmethylthioanilid-forbindelser, som er nyttige til inhibition af replikationen af HIV
TR200201128T2 (tr) PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
ATE251117T1 (de) Neue aminobenzophenone
TW200505926A (en) 1,4-diazabicyclo [3.2.2] nonanecarboxamide derivatives, preparation thereof and therapeutic use thereof
EP1144393A3 (en) Heterocyclic derivatives and their use as integrin inhibitor
AU6085699A (en) 2-arylalkylthio -imidazoles, 2-arylalkenyl -thio -imidazoles and 2-arylalkinyl -thio -imidazoles as anti -inflammatory substances and substances inhibiting the release of cytokine
CA2285535A1 (en) Benzimidazole derivative for treating allergy-related disease
BR0215911A (pt) Compostos 1,2,4-tiadiazol e utilização dos mesmos
TR199600181A2 (tr) 4-alkiltio-pirimidin-5-ilasetik asit türevleri.
EA200200379A2 (ru) Новые соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции
MXPA01011888A (es) Derivados de tetrazolinona.
TH72690A (th) การใช้อนุพันธ์ของ n-อะริลไฮดราซินเพื่อใช้ปราบแมลงมีภัยในตัวสัตว์และที่อยู่บนตัวสัตว์
ES2112774A1 (es) Nuevos derivados azolicos con actividad antifungica.