DK1214344T3 - Dipeptidylpeptidaser - Google Patents

Dipeptidylpeptidaser

Info

Publication number
DK1214344T3
DK1214344T3 DK00962085T DK00962085T DK1214344T3 DK 1214344 T3 DK1214344 T3 DK 1214344T3 DK 00962085 T DK00962085 T DK 00962085T DK 00962085 T DK00962085 T DK 00962085T DK 1214344 T3 DK1214344 T3 DK 1214344T3
Authority
DK
Denmark
Prior art keywords
nucleic acids
dipeptidyl peptidase
dipeptidyl
dpp8
dppiv
Prior art date
Application number
DK00962085T
Other languages
Danish (da)
English (en)
Inventor
Catherine Anne Abbott
Mark Douglas Gorell
Original Assignee
Univ Sydney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPQ2762A external-priority patent/AUPQ276299A0/en
Priority claimed from AUPQ5709A external-priority patent/AUPQ570900A0/en
Application filed by Univ Sydney filed Critical Univ Sydney
Application granted granted Critical
Publication of DK1214344T3 publication Critical patent/DK1214344T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK00962085T 1999-09-10 2000-09-11 Dipeptidylpeptidaser DK1214344T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPQ2762A AUPQ276299A0 (en) 1999-09-10 1999-09-10 Peptide and nucleic acid molecule
AUPQ5709A AUPQ570900A0 (en) 2000-02-18 2000-02-18 Peptide and nucleic acid molecule

Publications (1)

Publication Number Publication Date
DK1214344T3 true DK1214344T3 (da) 2006-11-06

Family

ID=25646142

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00962085T DK1214344T3 (da) 1999-09-10 2000-09-11 Dipeptidylpeptidaser

Country Status (9)

Country Link
US (2) US6881564B1 (enExample)
EP (1) EP1214344B1 (enExample)
JP (1) JP4748908B2 (enExample)
AT (1) ATE332366T1 (enExample)
CA (1) CA2384135A1 (enExample)
DE (1) DE60029230T2 (enExample)
DK (1) DK1214344T3 (enExample)
ES (1) ES2269178T3 (enExample)
WO (1) WO2001019866A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE357509T1 (de) * 1997-09-29 2007-04-15 Point Therapeutics Inc Stimulierung von hämatopoietischen zellen im vitro
US6979697B1 (en) * 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
ES2269178T3 (es) * 1999-09-10 2007-04-01 The University Of Sydney Dipeptidil peptidasas.
EP1280922A2 (en) * 2000-04-18 2003-02-05 Millennium Pharmaceuticals, Inc. 21953, a human prolyl oligopeptidase family member and uses thereof
US20040047853A1 (en) * 2000-06-09 2004-03-11 Dahl Soren W Purified proenzyme of dipeptidyl peptidase i (pro-dppi)
WO2002031134A2 (en) 2000-10-12 2002-04-18 Ferring Bv Novel serine protease genes related to dppiv
AUPR107800A0 (en) 2000-10-27 2000-11-23 University Of Sydney, The Peptide and nucleic acid molecule ii
DE10100053A1 (de) * 2001-01-02 2002-08-22 Keyneurotek Ag I G Verwendung von Enzyminhibitoren der Dipeptidylpeptidase IV sowie der Aminopeptidase N und pharmazeutischen Zubereitungen daraus zur Prävention und/oder Therapie Ischämie-bedingter akuter und chronischer neurodegenerativer Prozesse und Erkrankungen
WO2002066627A1 (en) * 2001-02-16 2002-08-29 Bayer Aktiengesellschaft Regulation of human dipeptidyl peptidase 8
DE60222667T2 (de) 2001-06-27 2008-07-17 Smithkline Beecham Corp. Fluorpyrrolidine als dipeptidylpeptidaseinhibitoren
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
CA2837936A1 (en) * 2001-11-26 2003-06-05 Trustees Of Tufts College Peptidomimetic inhibitors of post-proline cleaving enzymes
EP1528931B1 (en) 2002-08-09 2008-05-07 Prosidion Ltd. Dipeptidyl peptidase iv inhibitors for decreasing the rate of chronic weight gain
JP2007511467A (ja) 2003-05-14 2007-05-10 タケダ サン ディエゴ インコーポレイテッド ジペプチジルペプチダーゼインヒビター
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
KR20060041309A (ko) 2003-08-13 2006-05-11 다케다 야쿠힌 고교 가부시키가이샤 4-피리미돈 유도체 및 펩티딜 펩티다제 저해제로서의 그의용도
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
WO2005106021A1 (en) * 2004-04-28 2005-11-10 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 8 (dpp8)
WO2005108997A1 (en) * 2004-05-11 2005-11-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 6 (dpp6)
JP2008501714A (ja) 2004-06-04 2008-01-24 武田薬品工業株式会社 ジペプチジルペプチダーゼインヒビター
WO2006019965A2 (en) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
US20060063719A1 (en) * 2004-09-21 2006-03-23 Point Therapeutics, Inc. Methods for treating diabetes
ATE532518T1 (de) 2005-09-14 2011-11-15 Takeda Pharmaceutical Dipeptidyl-peptidase-hemmer zur behandlung von diabetes
CA2622642C (en) 2005-09-16 2013-12-31 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
EP1971614A1 (en) 2005-11-14 2008-09-24 Probiodrug AG Cyclopropyl-fused pyrrolidine derivatives as dipeptidyl peptidase iv inhibitors
WO2007112347A1 (en) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7728146B2 (en) 2006-04-12 2010-06-01 Probiodrug Ag Enzyme inhibitors
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
WO2016210395A1 (en) * 2015-06-26 2016-12-29 Dupont Nutrition Biosciences Aps Aminopeptidases for protein hydrlyzates
WO2018129497A1 (en) 2017-01-09 2018-07-12 Bioxcel Therapeutics, Inc. Predictive and diagnostic methods for prostate cancer
DE102018107224A1 (de) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977085A (en) * 1984-02-29 1990-12-11 The Board Of Regents Of The Univ. Of California Cloning and expression of yeast STE13 and Dpp2 genes encoding dipeptidyl aminopeptidase A and B
US5231126A (en) * 1985-04-01 1993-07-27 Shi Guan Yi Beta-crystalline form of isotactic polypropylene and method for forming the same
EP0958314B1 (en) * 1997-02-07 2002-11-06 ExxonMobil Chemical Patents Inc. Propylene polymers incorporating polyethylene macromers
US20040132158A1 (en) * 1999-01-11 2004-07-08 Incyte Corporation Human peptidases
ES2269178T3 (es) * 1999-09-10 2007-04-01 The University Of Sydney Dipeptidil peptidasas.
US6627723B2 (en) * 1999-12-22 2003-09-30 Exxonmobil Chemical Patents Inc. Adhesive alpha-olefin inter-polymers
US20030198953A1 (en) * 2000-03-30 2003-10-23 Spytek Kimberly A. Novel proteins and nucleic acids encoding same
WO2002031134A2 (en) * 2000-10-12 2002-04-18 Ferring Bv Novel serine protease genes related to dppiv
US20020123538A1 (en) * 2000-12-29 2002-09-05 Peiguang Zhou Hot-melt adhesive based on blend of amorphous and crystalline polymers for multilayer bonding
US6774069B2 (en) * 2000-12-29 2004-08-10 Kimberly-Clark Worldwide, Inc. Hot-melt adhesive for non-woven elastic composite bonding
US7700707B2 (en) * 2002-10-15 2010-04-20 Exxonmobil Chemical Patents Inc. Polyolefin adhesive compositions and articles made therefrom
US7550528B2 (en) * 2002-10-15 2009-06-23 Exxonmobil Chemical Patents Inc. Functionalized olefin polymers
CA2499951C (en) * 2002-10-15 2013-05-28 Peijun Jiang Multiple catalyst system for olefin polymerization and polymers produced therefrom
US7223822B2 (en) * 2002-10-15 2007-05-29 Exxonmobil Chemical Patents Inc. Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom

Also Published As

Publication number Publication date
US6881564B1 (en) 2005-04-19
ES2269178T3 (es) 2007-04-01
DE60029230D1 (de) 2006-08-17
CA2384135A1 (en) 2001-03-22
US20040191826A1 (en) 2004-09-30
WO2001019866A1 (en) 2001-03-22
US7148338B2 (en) 2006-12-12
EP1214344A4 (en) 2004-03-10
EP1214344B1 (en) 2006-07-05
DE60029230T2 (de) 2007-06-06
JP2003509041A (ja) 2003-03-11
EP1214344A1 (en) 2002-06-19
ATE332366T1 (de) 2006-07-15
JP4748908B2 (ja) 2011-08-17

Similar Documents

Publication Publication Date Title
DE60029230D1 (de) Dipeptidyl-peptidasen
PL369741A1 (en) Immunocytokines with modulated selectivity
MXPA02004666A (es) Gelatinas recombinantes.
DK1242452T3 (da) Kimære natriuretiske peptider
FI956075L (fi) Rekombinantti, ihon sarveiskerroksen kymotyptinen entsyymi (SCCE)
AU7381098A (en) Polypeptides having prolyl pipeptidyl aminopeptidase activity and nucleic acids encoding same
IL195338A0 (en) Optimized fc variants and methods for their generation
EP2333098A3 (en) Enzymes having alpha amylase activity and methods of use thereof
AU3246300A (en) Polypeptides having galactose oxidase activity and nucleic acids encoding same
WO2003011115A3 (en) Peptide-based multimeric targeted contrast agents
CA2315274A1 (en) Polypeptides having aminopeptidase activity and nucleic acids encoding same
CA95794S (en) Paving stone
WO2002059315A3 (en) Human nucleic acids and polypeptides and methods of use thereof
AU2001263269A1 (en) Long wavelength engineered fluorescent proteins
DK1157100T3 (da) Oxaloacetathydrolase-defekte svampeværtsceller
TR199800445A3 (tr) cdc25B geni yükselticisi, hazirlanisi ve kullanimi.
MXPA03004578A (es) Nuevos polipeptidos involucrados en respuesta inmune.
NO20003146D0 (no) Ketonperoksyd-derivater, deres fremstilling og anvendelse
ATE187890T1 (de) Ligandgerichtete enzyme-prodrug therapie
WO2001088137A3 (en) Human myd88 adapter-like protein and functional fragments thereof
IL126244A0 (en) Deutsches Zentrum fur Luft- und Raumfahrt e.v.
PE20399A1 (es) Muteina ob
IT246281Y1 (it) Guarnitura per mobili, in particolare guarnitura di collegamento.
TR200103219T2 (tr) Nöropatik ağrının iyileştirilmesinde kullanım için aroil aminoasil piroller
DK1196607T3 (da) Antibakterielt chlamysin B-protein, gen kodende derfor samt ekspressionssystem