DK1202743T3 - Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic uses - Google Patents

Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic uses

Info

Publication number
DK1202743T3
DK1202743T3 DK00931530T DK00931530T DK1202743T3 DK 1202743 T3 DK1202743 T3 DK 1202743T3 DK 00931530 T DK00931530 T DK 00931530T DK 00931530 T DK00931530 T DK 00931530T DK 1202743 T3 DK1202743 T3 DK 1202743T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical
cod
cosmetic
serine proteases
diseases
Prior art date
Application number
DK00931530T
Other languages
Danish (da)
Inventor
Jon Bragi Bjarnason
Original Assignee
Jon Bragi Bjarnason
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jon Bragi Bjarnason filed Critical Jon Bragi Bjarnason
Application granted granted Critical
Publication of DK1202743T3 publication Critical patent/DK1202743T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Birds (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Fish derived serine proteinases including trypsins and chymotrypsin derived from cod such as Atlantic cod is used for treating and/or preventing a variety of diseases and disorders such as inflammatory diseases, infectious diseases caused by viruses, bacteria and fungal species and diseases where a receptor binding mechanism is involved in the pathogenesis. Pharmaceutical and cosmetic compositions comprising the proteinases are described.
DK00931530T 1999-06-18 2000-06-15 Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic uses DK1202743T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IS5086 1999-06-18
PCT/IS2000/000005 WO2000078332A2 (en) 1999-06-18 2000-06-15 Fish serine proteinases and their pharmaceutical and cosmetic use
EP00931530A EP1202743B1 (en) 1999-06-18 2000-06-15 Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic use

Publications (1)

Publication Number Publication Date
DK1202743T3 true DK1202743T3 (en) 2005-02-14

Family

ID=36700558

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00931530T DK1202743T3 (en) 1999-06-18 2000-06-15 Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic uses

Country Status (19)

Country Link
US (1) US6846485B2 (en)
EP (1) EP1202743B1 (en)
JP (1) JP2003502071A (en)
KR (1) KR100699084B1 (en)
CN (1) CN1197617C (en)
AT (1) ATE278417T1 (en)
AU (1) AU779700B2 (en)
CA (1) CA2377357C (en)
DE (1) DE60014659T2 (en)
DK (1) DK1202743T3 (en)
ES (1) ES2231200T3 (en)
IS (1) IS2782B (en)
MX (1) MXPA01013246A (en)
NO (1) NO327283B1 (en)
NZ (1) NZ516632A (en)
PL (1) PL202532B1 (en)
PT (1) PT1202743E (en)
RU (1) RU2264824C2 (en)
WO (1) WO2000078332A2 (en)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003511093A (en) * 1999-10-20 2003-03-25 ノルデュール・イーエイチエフ Protein hydrolyzate produced using marine protease
US6632429B1 (en) 1999-12-17 2003-10-14 Joan M. Fallon Methods for treating pervasive development disorders
US8030002B2 (en) 2000-11-16 2011-10-04 Curemark Llc Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
US7026111B2 (en) * 2001-10-15 2006-04-11 Beckman Coulter, Inc. Methods and reagents for improved cell-based assays
US20050002897A1 (en) * 2003-06-18 2005-01-06 Ulrich Haupts Biological entities and the pharmaceutical or diagnostic use thereof
GB2403146B (en) * 2003-06-23 2007-07-11 Johnson & Johnson Medical Ltd Method of making a wound dressing comprising lactate oxidase
CN1882354B (en) * 2003-09-12 2012-07-04 捷通国际有限公司 Cytokine modulators and related methods of use
US7758903B2 (en) 2003-09-12 2010-07-20 Access Business Group International Llc Cytokine modulators and related methods of use
US7758902B2 (en) * 2003-09-12 2010-07-20 Access Business Group International Llc Cytokine modulators and related methods of use
GB0326194D0 (en) * 2003-11-10 2003-12-17 Univ Kent Canterbury Proteins involved in signal transduction
US20080058282A1 (en) 2005-08-30 2008-03-06 Fallon Joan M Use of lactulose in the treatment of autism
WO2007075853A2 (en) * 2005-12-20 2007-07-05 Swiss-American Products, Inc. Protease compositions for the treatment of damaged tissue
RU2355383C2 (en) * 2007-06-26 2009-05-20 Открытое акционерное общество "Московский комитет по науке и технологиям" ОАО "МКНТ" Microbial collagenase makeup preparation
CN101977626A (en) * 2008-01-21 2011-02-16 德莫迪斯公司 Use of serine protease inhibitors in the treatment of skin diseases
US8658163B2 (en) 2008-03-13 2014-02-25 Curemark Llc Compositions and use thereof for treating symptoms of preeclampsia
US8084025B2 (en) 2008-04-18 2011-12-27 Curemark Llc Method for the treatment of the symptoms of drug and alcohol addiction
FR2930727B1 (en) * 2008-04-30 2012-10-05 Evolution Dermatologique Lab COMPOSITION FOR THE TREATMENT OF SEBORRHEIC STATES.
US9320780B2 (en) 2008-06-26 2016-04-26 Curemark Llc Methods and compositions for the treatment of symptoms of Williams Syndrome
ES2732453T3 (en) 2008-07-01 2019-11-22 Curemark Llc Methods and compositions for the treatment of symptoms of neurological and mental health disorders
US10776453B2 (en) 2008-08-04 2020-09-15 Galenagen, Llc Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain
US20100092447A1 (en) 2008-10-03 2010-04-15 Fallon Joan M Methods and compositions for the treatment of symptoms of prion diseases
JP2010130920A (en) * 2008-12-03 2010-06-17 Shiseido Co Ltd Hyaluronic acid enzyme conjugate gel
EP2373693A4 (en) 2009-01-06 2012-04-25 Curelon Llc Compositions and methods for the treatment or the prevention oral infections by e. coli
GB2480772B (en) 2009-01-06 2013-10-16 Curelon Llc Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus
EP2226382A1 (en) 2009-03-03 2010-09-08 B.R.A.I.N. Biotechnology Research and Information Network AG Protease for wound conditioning and skin care
US9056050B2 (en) 2009-04-13 2015-06-16 Curemark Llc Enzyme delivery systems and methods of preparation and use
US9511125B2 (en) * 2009-10-21 2016-12-06 Curemark Llc Methods and compositions for the treatment of influenza
WO2012145651A2 (en) 2011-04-21 2012-10-26 Curemark, Llc Compounds for the treatment of neuropsychiatric disorders
CN103007258A (en) * 2011-09-22 2013-04-03 安淇生物控释技术(苏州)有限公司 Medical composition containing fish serine protease and antibacterial compound, and uses thereof
HUE030968T2 (en) 2012-01-23 2017-06-28 Restorsea Llc Cosmetic
US10350278B2 (en) 2012-05-30 2019-07-16 Curemark, Llc Methods of treating Celiac disease
CN103509809B (en) * 2013-09-25 2015-02-04 中山大学 Branchiostoma belcheri chitin-binding associated serine protease CASP gene for identifying chitin and application thereof
JP6089152B2 (en) 2013-12-13 2017-03-01 レスターシー エルエルシイＲｅｓｔｏｒｓｅａ， Ｌｌｃ Exfoliating hair retention promoting formulation
EP3932420A1 (en) * 2014-01-29 2022-01-05 Enzymatica AB Novel treatments
GB201405784D0 (en) 2014-03-31 2014-05-14 Enzymatica Ab Novel methods, polypeptides and uses thereof
AU2015259509A1 (en) 2014-05-16 2016-11-24 Restorsea, Llc Biphasic cosmetic
LT6177B (en) 2014-10-10 2015-07-27 Uab "Biocentras" ISOLATION OF ENZYME COMPLEXES FROM Streptomyces gougerotii 101, PREPARATION AND APPLICATION OF MULTIENZYME BIOPREPARATIONS
EP3120866A1 (en) * 2015-07-24 2017-01-25 Zymetech ehf. Use of marine serine proteases for removal, prevention and inhibition of formation and growth of biofilms
EP3121272A1 (en) * 2015-07-24 2017-01-25 Zymetech ehf. Novel fish trypsin isoforms and their use
RU2610669C1 (en) * 2015-10-16 2017-02-14 Общество с ограниченной ответственностью "Научно-исследовательский институт средств противоожоговой терапии" Method for production of proteolytic preparation for medical use
GB201701315D0 (en) 2017-01-26 2017-03-15 Enzymatica Ab Novel treatments
GB201800274D0 (en) 2018-01-08 2018-02-21 Enzymatica Ab Novel treatments
GB201801982D0 (en) 2018-02-07 2018-03-28 Enzymatica Ab Novel treatments
CN114174505A (en) * 2019-05-13 2022-03-11 比奥塞乌蒂卡有限公司 Purified fish proteases having high specific activity and methods for producing the same
US11541009B2 (en) 2020-09-10 2023-01-03 Curemark, Llc Methods of prophylaxis of coronavirus infection and treatment of coronaviruses
US11441261B2 (en) 2020-09-10 2022-09-13 WABESO Enhanced Enzymatics, Inc. Self-sterilizing fabrics incorporating anti-viral cold-active proteases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE454566B (en) * 1984-04-24 1988-05-16 Lars G I Hellgren PHARMACEUTICAL COMPOSITION CONTAINING AN ACTIVE AMOUNT OF WATER-SOLUBLE PROTEINASES EXTRACTED FROM A WATER-LIVING ANIMAL SELECTED BY THE EUPHAUSIACEAE OR GENERAL MALLOTUS
US6030612A (en) * 1994-11-22 2000-02-29 Phairson Medical Inc. Antimicrobial uses of multifunctional enzyme
US5958406A (en) * 1994-11-22 1999-09-28 Phairson Medical Inc. Acne treatment with multifunctional enzyme
US6232088B1 (en) * 1995-02-08 2001-05-15 Phairson Medical, Inc. Treatment and prevention of immune rejection reactions
JP2002515903A (en) * 1997-02-12 2002-05-28 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド Composition of serine protease and topical retinoid
AU2845400A (en) * 1998-12-24 2000-07-31 Phairson Medical Inc. Treatment and prevention of immune rejection reactions

Also Published As

Publication number Publication date
ATE278417T1 (en) 2004-10-15
CN1356907A (en) 2002-07-03
DE60014659D1 (en) 2004-11-11
CA2377357A1 (en) 2000-12-28
IS6194A (en) 2001-12-10
US20020141987A1 (en) 2002-10-03
NO20016159D0 (en) 2001-12-17
KR100699084B1 (en) 2007-03-23
US6846485B2 (en) 2005-01-25
CN1197617C (en) 2005-04-20
EP1202743B1 (en) 2004-10-06
ES2231200T3 (en) 2005-05-16
IS2782B (en) 2012-05-15
AU4947800A (en) 2001-01-09
PL352318A1 (en) 2003-08-11
AU779700B2 (en) 2005-02-10
NO20016159L (en) 2001-12-17
WO2000078332A2 (en) 2000-12-28
DE60014659T2 (en) 2006-03-02
JP2003502071A (en) 2003-01-21
NZ516632A (en) 2004-04-30
EP1202743A2 (en) 2002-05-08
MXPA01013246A (en) 2003-08-20
KR20020025082A (en) 2002-04-03
WO2000078332A3 (en) 2001-07-05
PT1202743E (en) 2005-02-28
NO327283B1 (en) 2009-06-02
PL202532B1 (en) 2009-07-31
RU2264824C2 (en) 2005-11-27
CA2377357C (en) 2013-07-23

Similar Documents

Publication Publication Date Title
DK1202743T3 (en) Pharmaceutical and cosmetic compositions comprising cod serine proteases and their pharmaceutical and cosmetic uses
TR200400072T4 (en) Novel Biarylcarboxamides Biarylcarboxamide Nouveaux Biarylcarboxamides
NO20030845D0 (en) Selected fused pyrrolocarbazoles
DK1257175T3 (en) Use of Acid Stable Subtilisin Proteases in Animal Feeds.
DE602004018338D1 (en) PREVENTION AND TREATMENT OF INFLAMMATORY AND / OR IMMUNE-RELATED BONE WOOD
NO952863D0 (en) Fluoxetine Pharmaceutical Compositions
BG66080B1 (en) Substituted thioacetamides
DK1556021T3 (en) Pharmaceutical compositions comprising flavonoids and menthol as well as methods of treatment using said compositions
DK0793674T3 (en) Inhibitors of human neutrophil elastase
ATE443043T1 (en) PHENYLCARBOXAMIDE AS A BETA-SECRETASE INHIBITOR FOR THE TREATMENT OF ALZHEIMER'S
CY1107342T1 (en) USE OF NITRIL PRODUCERS AS MEDICINE
ATE297188T1 (en) STABILIZED ASCORBIC ACID SOLUTIONS
TW200716226A (en) Compositions comprising actinidia and methods of use thereof
ATE319439T1 (en) AGENTS FOR THE TREATMENT OF DISEASES OF THE TRACHEO-BRONCHIAL TRACT, IN PARTICULAR COPD
MXPA03010179A (en) Arylsulfonamide ethers, and methods of use thereof.
ATE361914T1 (en) CATHEPSINCYSTEINE PROTEASE INHIBITORS AND THEIR USE IN THE TREATMENT OF INFLAMMATION AND IMMUNE DISEASES
DE60131968D1 (en) PYRANOE2,3-CIMIDAZOÄ1,2-ATPYRIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISEASES
BR9808210A (en) Befenyloxazolines dissubstituted
ATE390144T1 (en) TREATMENT OF FIBROSIS
DK1196579T3 (en) tryptase inhibitor
DE50115198D1 (en) ANTI-HELMINTICA FOR PREVENTING PARASITIC INFECTION IN HUMANS AND ANIMALS
WO2002023784A3 (en) Cysteine protease inhibitors
TH53171B (en) The use of acid-stable proteases in animal feed
ATE279195T1 (en) ANTHELMINTICS FOR PREVENTING PARASITIC INFECTIONS IN HUMAN AND ANIMALS III
AU9683401A (en) Flea peritrophin nucleic acid molecules, proteins and uses thereof