DK1187846T3 - 11beta-langkædet-substituerede estratriener, fremgangsmåde til fremstilling heraf, farmaceutiske præparater, der indeholder disse 11beta-langkædet-substituerede estratriener samt deres anvendelse til fremstilling af lægemidler - Google Patents

11beta-langkædet-substituerede estratriener, fremgangsmåde til fremstilling heraf, farmaceutiske præparater, der indeholder disse 11beta-langkædet-substituerede estratriener samt deres anvendelse til fremstilling af lægemidler

Info

Publication number
DK1187846T3
DK1187846T3 DK00947882T DK00947882T DK1187846T3 DK 1187846 T3 DK1187846 T3 DK 1187846T3 DK 00947882 T DK00947882 T DK 00947882T DK 00947882 T DK00947882 T DK 00947882T DK 1187846 T3 DK1187846 T3 DK 1187846T3
Authority
DK
Denmark
Prior art keywords
11beta
long chain
chain substituted
substituted estratrienes
pharmaceuticals
Prior art date
Application number
DK00947882T
Other languages
English (en)
Inventor
Rolf Bohlmann
Nikolaus Heinrich
Jorg Kroll
Karl-Heinrich Fritzemeier
Rosemarie Lichtner
Gerhard Sauer
Christa Hegele-Hartung
Jens Hoffmann
Ludwig Zorn
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1187846T3 publication Critical patent/DK1187846T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Led Device Packages (AREA)
  • Led Devices (AREA)
DK00947882T 1999-06-24 2000-06-26 11beta-langkædet-substituerede estratriener, fremgangsmåde til fremstilling heraf, farmaceutiske præparater, der indeholder disse 11beta-langkædet-substituerede estratriener samt deres anvendelse til fremstilling af lægemidler DK1187846T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19929715A DE19929715A1 (de) 1999-06-24 1999-06-24 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP2000/005969 WO2001000652A2 (de) 1999-06-24 2000-06-26 11β-LANGKETTIG-SUBSTITUIERTE ESTRATRIENE, VERFAHREN ZUR HERSTELLUNG, PHARMAZEUTISCHE PRÄPARATE, DIE DIESE 11β-LANGKETTIG-SUBSTITUIERTEN ESTRATRIENE ENTHALTEN, SOWIE DEREN VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN

Publications (1)

Publication Number Publication Date
DK1187846T3 true DK1187846T3 (da) 2007-07-02

Family

ID=7912903

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00947882T DK1187846T3 (da) 1999-06-24 2000-06-26 11beta-langkædet-substituerede estratriener, fremgangsmåde til fremstilling heraf, farmaceutiske præparater, der indeholder disse 11beta-langkædet-substituerede estratriener samt deres anvendelse til fremstilling af lægemidler

Country Status (11)

Country Link
US (1) US6790842B1 (da)
EP (1) EP1187846B1 (da)
JP (1) JP2003503419A (da)
AT (1) ATE360027T1 (da)
AU (1) AU6152400A (da)
DE (2) DE19929715A1 (da)
DK (1) DK1187846T3 (da)
ES (1) ES2283307T3 (da)
NO (1) NO323372B1 (da)
PT (1) PT1187846E (da)
WO (1) WO2001000652A2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070129282A1 (en) * 1998-11-24 2007-06-07 Ahlem Clarence N Pharmaceutical treatments and compositions
DK1955700T3 (da) 1999-09-30 2011-05-23 Harbor Biosciences Inc Terapeutisk behandling af androgenreceptor-betingede lidelser
CN100538944C (zh) * 2001-04-12 2009-09-09 昭和电工株式会社 铌电容器的制备方法
DE10214179A1 (de) * 2002-03-27 2003-10-16 Schering Ag 11beta-substituierte 19-Nor-17alpha-pregna-1,3,5(10)-trien-17beta-ole mit einem 21,16alpha-Laktonring
CA2522784C (en) * 2003-04-01 2012-06-19 Hollis-Eden Pharmaceuticals, Inc. Antiandrogens with marginal agonist activity and methods of use
DE102006054535A1 (de) * 2006-11-15 2008-05-21 Bayer Schering Pharma Aktiengesellschaft Progesteronrezeptorantagonisten
WO2011092127A1 (en) 2010-01-26 2011-08-04 Bayer Schering Pharma Aktiengesellschaft 14,17-bridged estratriene derivatives comprising heterocyclic bioisosteres for the phenolic a-ring

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640977A2 (en) 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
DE69128820T2 (de) * 1990-08-14 1998-06-10 Hoechst Marion Roussel Inc Neue 19-Nor Steroide, die eine Amid tragende Gruppe in der 11-Beta-Stelle haben, ihre Herstellung, ihre Verwendung als Medikamente und pharmazeutische Präparate davon
FR2685332A1 (fr) * 1991-12-20 1993-06-25 Roussel Uclaf Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments.
US5965551A (en) 1996-02-21 1999-10-12 North Carolina State University Method of treating alopecia
FR2757399B1 (fr) * 1996-12-23 1999-12-17 Hoechst Marion Roussel Inc Application de composes steroides substitues en 11 pour la fabrication de medicaments ayant une activite estrogene dissociee
FR2757519B1 (fr) 1996-12-23 1999-06-11 Hoechst Marion Roussel Inc Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
FR2771096B1 (fr) * 1997-11-17 2000-08-11 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
DE69902684T2 (de) 1998-11-20 2003-04-24 Akzo Nobel Nv Estrogenische estra-1,3,5(10)-trien verbindungen mit verschiedenen wirkungen auf estrogenrezeptor alpha und beta mit einer unverzweigten kohlenwasserstoffkette von 5-9 kohlenstoffatomen in position 11

Also Published As

Publication number Publication date
PT1187846E (pt) 2007-05-31
ATE360027T1 (de) 2007-05-15
EP1187846B1 (de) 2007-04-18
NO323372B1 (no) 2007-04-16
WO2001000652A2 (de) 2001-01-04
DE19929715A1 (de) 2000-12-28
EP1187846A2 (de) 2002-03-20
WO2001000652A3 (de) 2001-05-10
ES2283307T3 (es) 2007-11-01
NO20016330D0 (no) 2001-12-21
JP2003503419A (ja) 2003-01-28
NO20016330L (no) 2002-01-31
AU6152400A (en) 2001-01-31
DE50014263D1 (de) 2007-05-31
US6790842B1 (en) 2004-09-14

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