DK1165543T3 - Fremgangsmåde til fremstilling af [S-(R*,S*)]-G(B)-[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinpropansyre og derivater deraf - Google Patents
Fremgangsmåde til fremstilling af [S-(R*,S*)]-G(B)-[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinpropansyre og derivater derafInfo
- Publication number
- DK1165543T3 DK1165543T3 DK00916573T DK00916573T DK1165543T3 DK 1165543 T3 DK1165543 T3 DK 1165543T3 DK 00916573 T DK00916573 T DK 00916573T DK 00916573 T DK00916573 T DK 00916573T DK 1165543 T3 DK1165543 T3 DK 1165543T3
- Authority
- DK
- Denmark
- Prior art keywords
- piperidinyl
- oxo
- carbonyl
- propyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12567199P | 1999-03-22 | 1999-03-22 | |
| PCT/US2000/007462 WO2000056730A1 (en) | 1999-03-22 | 2000-03-21 | PROCESS FOR PREPARING [S-(R*,S*)] -β -[[[1-[1-OXO-3- (4-PIPERIDINYL) PROPYL] -3-PIPERIDINYL] CARBONYL] AMINO] -3- PYRIDINEPROPANOIC ACID AND DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1165543T3 true DK1165543T3 (da) | 2003-09-29 |
Family
ID=22420863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00916573T DK1165543T3 (da) | 1999-03-22 | 2000-03-21 | Fremgangsmåde til fremstilling af [S-(R*,S*)]-G(B)-[[1-[1-oxo-3-(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinpropansyre og derivater deraf |
Country Status (22)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002540101A (ja) | 1999-03-22 | 2002-11-26 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | プロピオン酸３−アミノ−３−アリールの合成 |
| SI1430057T1 (sl) * | 2001-09-21 | 2006-02-28 | Sanofi Aventis | Substituirani 2-piridinil-6,7,8,9-tetrahidropirimido -(1,2-a)pirimidin-4-onski in 7-piridinil-2,3-dihidroimidazo -(1,2-a)pirimidin-5(1H)onski derivati |
| DK2744802T3 (en) | 2011-08-17 | 2017-04-03 | Piramal Imaging Sa | CONNECTIONS FOR BINDING TO THE TROMBOCYTE SPECIFIC GLYCOPROTEIN IIB / IIIA AND ITS APPLICATION FOR IMAGE DIAGNOSIS OF TROMBER |
| WO2014124943A1 (en) | 2013-02-12 | 2014-08-21 | Bayer Pharma Aktiengesellschaft | Metal chelate compounds for binding to the platelet specific glycoprotein iib/iiia |
| ES2777200T3 (es) | 2013-02-20 | 2020-08-04 | Reuter Chemische Apparatenbau Ek | Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente |
| WO2014173855A1 (en) | 2013-04-22 | 2014-10-30 | Reuter Chemische Apparatebau Kg | Process for preparing enantiomerically enriched 3-hydroxymethylpiperidine |
| KR102548998B1 (ko) | 2020-03-31 | 2023-06-29 | 재단법인 아산사회복지재단 | 혈전영상을 위한 방사성의약품 및 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58243B1 (en) | 1983-12-07 | 1993-08-11 | Lonza Ag | A process for the preparation of optically-active 3-amino carboxylic acids |
| US5254573A (en) | 1991-10-15 | 1993-10-19 | Monsanto Company | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors |
| DK0669912T3 (da) * | 1993-09-22 | 2002-03-04 | Fujisawa Pharmaceutical Co | N-(3-Piperidinylcarbonyl)-beta-alaninderivater som PAF-antagonister |
| US5770575A (en) * | 1994-03-16 | 1998-06-23 | Ortho Pharmaceutical Corporation | Nipecotic acid derivatives as antithrombotic compounds |
| EP0888302A1 (en) * | 1996-03-13 | 1999-01-07 | Fujisawa Pharmaceutical Co., Ltd. | N- (r)-1- 3-(4-piperidyl)propionyl-3-piperidylcarbonyl]-2(s)-acetylamino-beta-alanine as fibrinogen receptor antagonist |
| RU2194038C2 (ru) * | 1996-05-01 | 2002-12-10 | Орто-Макнейл Фармасьютикал, Инк. | Карбоксамидные производные пирролидина или пиперидина, фармацевтическая композиция на их основе и способ ингибирования агрегации тромбоцитов |
| ATE209179T1 (de) | 1996-07-12 | 2001-12-15 | Searle & Co | Asymmetrische synthese von chiralen beta- aminosäuren |
| US6066651A (en) * | 1997-10-29 | 2000-05-23 | Ortho-Mcneil Pharmaceutical, Inc. | Orally-active nipecotamide glycolamide esters for the treatment of thrombosis disorders |
-
2000
- 2000-03-21 SK SK1356-2001A patent/SK13562001A3/sk unknown
- 2000-03-21 CN CN00807617A patent/CN1351600A/zh active Pending
- 2000-03-21 HK HK02107463.1A patent/HK1046272A1/zh unknown
- 2000-03-21 CZ CZ20013431A patent/CZ20013431A3/cs unknown
- 2000-03-21 PT PT00916573T patent/PT1165543E/pt unknown
- 2000-03-21 JP JP2000606591A patent/JP2002540108A/ja active Pending
- 2000-03-21 AT AT00916573T patent/ATE242235T1/de not_active IP Right Cessation
- 2000-03-21 EP EP00916573A patent/EP1165543B1/en not_active Expired - Lifetime
- 2000-03-21 DE DE60003169T patent/DE60003169T2/de not_active Expired - Fee Related
- 2000-03-21 ES ES00916573T patent/ES2199805T3/es not_active Expired - Lifetime
- 2000-03-21 DK DK00916573T patent/DK1165543T3/da active
- 2000-03-21 AU AU37661/00A patent/AU775413B2/en not_active Ceased
- 2000-03-21 WO PCT/US2000/007462 patent/WO2000056730A1/en not_active Ceased
- 2000-03-21 MX MXPA01009615A patent/MXPA01009615A/es unknown
- 2000-03-21 KR KR1020017012100A patent/KR20020019895A/ko not_active Withdrawn
- 2000-03-21 HR HR20010767A patent/HRP20010767A2/hr not_active Application Discontinuation
- 2000-03-21 YU YU74601A patent/YU74601A/sh unknown
- 2000-03-21 BR BR0010652-6A patent/BR0010652A/pt not_active IP Right Cessation
- 2000-03-21 UA UA2001096538A patent/UA67832C2/uk unknown
- 2000-03-21 HU HU0201262A patent/HUP0201262A3/hu unknown
- 2000-03-21 US US09/532,375 patent/US6515130B1/en not_active Expired - Lifetime
- 2000-03-21 CA CA002368024A patent/CA2368024A1/en not_active Abandoned
-
2002
- 2002-02-22 US US10/081,289 patent/US20020137937A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000056730A1 (en) | 2000-09-28 |
| MXPA01009615A (es) | 2003-07-21 |
| DE60003169T2 (de) | 2005-10-27 |
| HUP0201262A3 (en) | 2003-12-29 |
| ES2199805T3 (es) | 2004-03-01 |
| HRP20010767A2 (en) | 2002-12-31 |
| AU3766100A (en) | 2000-10-09 |
| CZ20013431A3 (cs) | 2003-04-16 |
| JP2002540108A (ja) | 2002-11-26 |
| EP1165543A1 (en) | 2002-01-02 |
| HUP0201262A2 (en) | 2002-08-28 |
| CN1351600A (zh) | 2002-05-29 |
| KR20020019895A (ko) | 2002-03-13 |
| YU74601A (sh) | 2004-05-12 |
| UA67832C2 (uk) | 2004-07-15 |
| US20020137937A1 (en) | 2002-09-26 |
| AU775413B2 (en) | 2004-07-29 |
| EP1165543B1 (en) | 2003-06-04 |
| SK13562001A3 (sk) | 2002-08-06 |
| ATE242235T1 (de) | 2003-06-15 |
| US6515130B1 (en) | 2003-02-04 |
| HK1046272A1 (zh) | 2003-01-03 |
| CA2368024A1 (en) | 2000-09-28 |
| DE60003169D1 (de) | 2003-07-10 |
| PT1165543E (pt) | 2003-10-31 |
| BR0010652A (pt) | 2002-07-16 |
| HU0201262D0 (cg-RX-API-DMAC7.html) | 2002-05-29 |
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