DK115925B - Fremgangsmåde til fremstilling af β-karbolinderivater. - Google Patents

Fremgangsmåde til fremstilling af β-karbolinderivater.

Info

Publication number
DK115925B
DK115925B DK508466AA DK508466A DK115925B DK 115925 B DK115925 B DK 115925B DK 508466A A DK508466A A DK 508466AA DK 508466 A DK508466 A DK 508466A DK 115925 B DK115925 B DK 115925B
Authority
DK
Denmark
Prior art keywords
preparation
carboline derivatives
carboline
derivatives
Prior art date
Application number
DK508466AA
Other languages
English (en)
Inventor
J Atkinson
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of DK115925B publication Critical patent/DK115925B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK508466AA 1964-09-16 1966-09-30 Fremgangsmåde til fremstilling af β-karbolinderivater. DK115925B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB37844/64A GB1055203A (en) 1964-09-16 1964-09-16 -ß-carboline derivatives, a process for their manufacture, and compositions containing them
GB3784564 1964-09-16

Publications (1)

Publication Number Publication Date
DK115925B true DK115925B (da) 1969-11-24

Family

ID=26263602

Family Applications (2)

Application Number Title Priority Date Filing Date
DK508366AA DK115924B (da) 1964-09-16 1966-09-30 Fremgangsmåde til fremstilling af β-karbolinderivater.
DK508466AA DK115925B (da) 1964-09-16 1966-09-30 Fremgangsmåde til fremstilling af β-karbolinderivater.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK508366AA DK115924B (da) 1964-09-16 1966-09-30 Fremgangsmåde til fremstilling af β-karbolinderivater.

Country Status (6)

Country Link
US (1) US3328412A (da)
BE (1) BE669716A (da)
DK (2) DK115924B (da)
FR (2) FR1453532A (da)
GB (1) GB1055203A (da)
NL (1) NL6512087A (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455044A1 (fr) * 1979-04-26 1980-11-21 Synthelabo Pyrido-indoles et leur application en therapeutique
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
UA74826C2 (en) * 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors
ES2211295B1 (es) * 2002-07-19 2005-12-01 Consejo Sup. De Investig. Cientificas Tetrahidro-beta-carbolinas fenolicas como antioxidantes.
DE10252667A1 (de) 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
EP1628977B1 (en) * 2003-04-29 2008-11-12 Oscient Pharmaceuticals ANTIBIOTIC TETRAHYDRO-b-CARBOLINE DERIVATIVES
SG184755A1 (en) * 2004-03-15 2012-10-30 Ptc Therapeutics Inc Carboline derivatives useful in the inhibition of angiogenesis
DE102004039382A1 (de) * 2004-08-13 2006-02-23 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE102005016460A1 (de) * 2005-04-11 2006-10-19 Grünenthal GmbH Spriocyclische Cyclohexanderivate zur Behandlung von Substanzabhängigkeit
DE102007009235A1 (de) 2007-02-22 2008-09-18 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
EP2225250A2 (en) 2007-11-30 2010-09-08 Biota Scientific Management Pty Ltd Bicyclic ppat inhibitors as antibacterial agents
BR122013017393A2 (pt) 2008-03-27 2019-10-15 Grünenthal GmbH Compostos derivados substituídos de 4-aminociclohexano, medicamentos contendo pelo menos um composto e uso dos referidos compostos
JP5542119B2 (ja) 2008-03-27 2014-07-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング スピロ(5.5)ウンデカン誘導体
WO2009118174A1 (de) 2008-03-27 2009-10-01 Grünenthal GmbH Substituierte cyclohexyldiamine
CN102046591B (zh) 2008-03-27 2014-12-03 格吕伦塔尔有限公司 羟甲基环己胺
CN102046633B (zh) 2008-03-27 2015-03-25 格吕伦塔尔有限公司 取代的螺环状环己烷衍生物
CN102459263A (zh) 2009-05-27 2012-05-16 Ptc医疗公司 取代的四氢β-咔啉的制备工艺
US8697662B2 (en) 2009-05-27 2014-04-15 Ptc Therapeutics, Inc. Methods for treating Kaposi sarcoma
CA3080983C (en) 2009-05-27 2023-02-28 Pct Therapeutics, Inc. Method of inhibiting and reducing a viral infection
WO2010138685A1 (en) 2009-05-27 2010-12-02 Ptc Therapeutics, Inc. Methods for treating prostate conditions
CN104327066B (zh) * 2014-09-30 2017-05-24 华东理工大学 快速高效提取卡柏林类生物碱的方法
WO2019028171A1 (en) 2017-08-01 2019-02-07 Ptc Therapeutics, Inc. DHODH INHIBITOR FOR USE IN THE TREATMENT OF HEMATOLOGICAL CANCERS
CN109528718B (zh) * 2018-12-12 2020-11-24 孙凤永 一种治疗宫颈癌的药物及其用途

Also Published As

Publication number Publication date
NL6512087A (da) 1966-03-17
US3328412A (en) 1967-06-27
GB1055203A (en) 1967-01-18
BE669716A (da) 1966-03-16
DK115924B (da) 1969-11-24
FR5569M (da) 1967-11-27
FR1453532A (fr) 1966-06-03

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