DK1137410T3 - Hidtil ukendte 4-dedimethylaminotetracyclinderivater - Google Patents
Hidtil ukendte 4-dedimethylaminotetracyclinderivaterInfo
- Publication number
- DK1137410T3 DK1137410T3 DK99967109T DK99967109T DK1137410T3 DK 1137410 T3 DK1137410 T3 DK 1137410T3 DK 99967109 T DK99967109 T DK 99967109T DK 99967109 T DK99967109 T DK 99967109T DK 1137410 T3 DK1137410 T3 DK 1137410T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- newly known
- dedimethylaminotetracycline
- dedimethylaminotetracycline derivatives
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/82—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/20—Diazonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
- C07C247/16—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C247/18—Compounds containing azido groups with azido groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
- C07C329/12—Dithiocarbonic acids; Derivatives thereof
- C07C329/14—Esters of dithiocarbonic acids
- C07C329/20—Esters of dithiocarbonic acids having sulfur atoms of dithiocarbonic groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19501398A | 1998-11-18 | 1998-11-18 | |
US10894898P | 1998-11-18 | 1998-11-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1137410T3 true DK1137410T3 (da) | 2006-12-27 |
Family
ID=26806459
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99967109T DK1137410T3 (da) | 1998-11-18 | 1999-11-18 | Hidtil ukendte 4-dedimethylaminotetracyclinderivater |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP1137410B1 (da) |
JP (3) | JP5060685B2 (da) |
KR (1) | KR100701635B1 (da) |
AT (1) | ATE336238T1 (da) |
AU (1) | AU766200B2 (da) |
CA (1) | CA2351703C (da) |
CY (1) | CY1106224T1 (da) |
DE (1) | DE69932846T2 (da) |
DK (1) | DK1137410T3 (da) |
ES (1) | ES2272097T3 (da) |
NZ (1) | NZ511194A (da) |
PT (1) | PT1137410E (da) |
WO (1) | WO2000028983A1 (da) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6946453B2 (en) | 1998-11-18 | 2005-09-20 | Collagenex Pharmaceuticals, Inc. | 4-dedimethylaminotracycline derivatives |
US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
AU766200B2 (en) * | 1998-11-18 | 2003-10-09 | Collagenex Pharmaceuticals, Inc. | Novel 4-dedimethy laminotetra cycline derivatives |
WO2002004404A2 (en) * | 2000-07-07 | 2002-01-17 | Trustees Of Tufts College | 7,8 and 9-substituted tetracycline compounds |
CA2415718C (en) * | 2000-07-07 | 2012-08-28 | Trustees Of Tufts College | 7-substituted tetracycline compounds |
US6846939B2 (en) * | 2000-07-07 | 2005-01-25 | Paratek Pharmaceuticals, Inc. | 9-substituted minocycline compounds |
US7553828B2 (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
BR0116935A (pt) * | 2001-03-13 | 2005-04-12 | Paratek Pharm Innc | Composto de tetraciclina, método para tratar um estado responsivo à tetraciclina em um indivìduo, e, composição farmacêutica |
WO2002072506A2 (en) | 2001-03-13 | 2002-09-19 | Paratek Pharmaceuticals, Inc. | 7-pyrollyl tetracycline compounds and methods of use thereof |
US7211267B2 (en) | 2001-04-05 | 2007-05-01 | Collagenex Pharmaceuticals, Inc. | Methods of treating acne |
NZ529308A (en) * | 2001-04-05 | 2005-03-24 | Collagenex Pharm Inc | Tetracycline compounds comprising a tetracycline and a controlled release agent to provide delivery at a dose below that required for antibiotic activity |
NZ528197A (en) * | 2001-04-05 | 2007-04-27 | Collagenex Pharm Inc | Use of a tetracycline compound of treating acne |
ATE455092T1 (de) * | 2001-04-24 | 2010-01-15 | Paratek Pharm Innc | Substituierte tetracyclin-verbindungen zur behandlung von malaria |
US8088820B2 (en) | 2001-04-24 | 2012-01-03 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for the treatment of malaria |
EP2332546A1 (en) | 2001-07-13 | 2011-06-15 | Paratek Pharmaceuticals, Inc. | Tetracyclines for the treatment of stroke |
AU2002365120A1 (en) | 2001-08-02 | 2003-07-15 | Paratek Pharmaceuticals, Inc. | Medicaments |
CN1961885A (zh) * | 2001-10-05 | 2007-05-16 | 泰特拉吉尼克斯医药公司 | 四环素衍生物在制药中的应用 |
EP2311796A1 (en) * | 2002-01-08 | 2011-04-20 | Paratek Pharmaceuticals, Inc. | 4-dedimethylamino tetracycline compounds |
EP1496742B1 (en) * | 2002-03-29 | 2010-11-24 | The Research Foundation Of State University Of New York | Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins |
US8173624B2 (en) | 2002-10-24 | 2012-05-08 | Paratek Pharmaceuticals, Inc. | Methods of using substituted tetracycline compounds to modulate RNA |
EP2277504A1 (en) * | 2002-10-24 | 2011-01-26 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for the treatment of malaria |
CN101786991A (zh) | 2003-07-09 | 2010-07-28 | 帕拉特克药品公司 | 取代的四环素化合物 |
EP2026776A2 (en) | 2006-05-15 | 2009-02-25 | Paratek Pharmaceuticals, Inc. | Methods of regulating expression of genes or of gene products using substituted tetracycline compounds |
ES2388958T3 (es) | 2007-11-29 | 2012-10-22 | Actelion Pharmaceuticals Ltd. | Derivados de acido fosfonico y su uso como antagonista del receptor P2Y12 |
PT2271348T (pt) | 2008-03-28 | 2018-04-16 | Paratek Pharm Innc | Formulação de comprimido oral de composto de tetraciclina |
TW202332671A (zh) | 2008-05-23 | 2023-08-16 | 美商Prtk Spv2公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
CN110156624B (zh) * | 2019-05-29 | 2022-03-08 | 河北冀衡药业股份有限公司 | 一种米诺环素及其衍生物的合成方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2786077A (en) * | 1954-10-22 | 1957-03-19 | Pfizer & Co C | Desdimethylaminotetracyclines and process |
DE1088481B (de) * | 1958-01-29 | 1960-09-08 | American Cyanamid Co | Verfahren zur Herstellung neuer Verbindungen der Tetracyclinreihe |
US3375276A (en) * | 1963-06-24 | 1968-03-26 | Squibb & Sons Inc | Method for preparing tetracycline products |
US3159675A (en) * | 1963-12-10 | 1964-12-01 | American Cyanamid Co | Novel 4-dedimethylamino-4-oxo-6-demethyltetracycline-4-oximes and 4-hydrazones |
US3247226A (en) * | 1964-07-06 | 1966-04-19 | American Cyanamid Co | 4-dimethylamino and 4-hydroxytetracycloxides |
US3345370A (en) * | 1965-03-16 | 1967-10-03 | American Cyanamid Co | 4-(n-mono-substituted) hydrazones of 4-dedimethylamino-4-oxo-tetracycline |
US3849493A (en) * | 1966-08-01 | 1974-11-19 | Pfizer | D-ring substituted 6-deoxytetracyclines |
US3824285A (en) * | 1967-09-13 | 1974-07-16 | Pfizer | 4-oxo-4-dedimethylaminotetracycline-4,6-hemiketals |
US5122519A (en) * | 1989-06-27 | 1992-06-16 | American Cyanamid Company | Stable, cosmetically acceptable topical gel formulation and method of treatment for acne |
US5045538A (en) * | 1990-06-28 | 1991-09-03 | The Research Foundation Of State University Of New York | Inhibition of wasting and protein degradation of mammalian muscle by tetracyclines |
US5442059A (en) * | 1992-08-13 | 1995-08-15 | American Cyanamid Company | 9-[(substituted glycyl)amido)]-6-demethyl-6-deoxytetracyclines |
EP1124558A4 (en) * | 1998-09-28 | 2004-10-27 | Res Foundation Ofstate Univers | NEW INHIBITANT AGAINST CATARACT EDUCATION |
AU766200B2 (en) * | 1998-11-18 | 2003-10-09 | Collagenex Pharmaceuticals, Inc. | Novel 4-dedimethy laminotetra cycline derivatives |
-
1999
- 1999-11-18 AU AU23456/00A patent/AU766200B2/en not_active Ceased
- 1999-11-18 ES ES99967109T patent/ES2272097T3/es not_active Expired - Lifetime
- 1999-11-18 DE DE69932846T patent/DE69932846T2/de not_active Expired - Lifetime
- 1999-11-18 AT AT99967109T patent/ATE336238T1/de active
- 1999-11-18 JP JP2000582031A patent/JP5060685B2/ja not_active Expired - Fee Related
- 1999-11-18 WO PCT/US1999/027304 patent/WO2000028983A1/en active IP Right Grant
- 1999-11-18 PT PT99967109T patent/PT1137410E/pt unknown
- 1999-11-18 NZ NZ511194A patent/NZ511194A/en not_active IP Right Cessation
- 1999-11-18 DK DK99967109T patent/DK1137410T3/da active
- 1999-11-18 EP EP99967109A patent/EP1137410B1/en not_active Expired - Lifetime
- 1999-11-18 EP EP06076306A patent/EP1743632A1/en not_active Withdrawn
- 1999-11-18 KR KR1020017006216A patent/KR100701635B1/ko not_active IP Right Cessation
- 1999-11-18 CA CA002351703A patent/CA2351703C/en not_active Expired - Fee Related
-
2006
- 2006-10-30 CY CY20061101555T patent/CY1106224T1/el unknown
-
2009
- 2009-09-30 JP JP2009228453A patent/JP2010043102A/ja active Pending
-
2010
- 2010-10-25 JP JP2010238591A patent/JP5130417B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2011021032A (ja) | 2011-02-03 |
CA2351703A1 (en) | 2000-05-25 |
PT1137410E (pt) | 2007-01-31 |
ATE336238T1 (de) | 2006-09-15 |
JP5130417B2 (ja) | 2013-01-30 |
WO2000028983A1 (en) | 2000-05-25 |
CY1106224T1 (el) | 2011-06-08 |
JP2010043102A (ja) | 2010-02-25 |
ES2272097T3 (es) | 2007-04-16 |
EP1137410B1 (en) | 2006-08-16 |
EP1137410A1 (en) | 2001-10-04 |
KR100701635B1 (ko) | 2007-03-30 |
NZ511194A (en) | 2003-08-29 |
CA2351703C (en) | 2008-12-30 |
EP1743632A1 (en) | 2007-01-17 |
AU766200B2 (en) | 2003-10-09 |
AU2345600A (en) | 2000-06-05 |
JP2002529501A (ja) | 2002-09-10 |
EP1137410A4 (en) | 2002-06-26 |
DE69932846T2 (de) | 2007-03-15 |
DE69932846D1 (de) | 2006-09-28 |
KR20010082303A (ko) | 2001-08-29 |
JP5060685B2 (ja) | 2012-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1137410T3 (da) | Hidtil ukendte 4-dedimethylaminotetracyclinderivater | |
NO20014925D0 (no) | Farmasöytiske forbindelser | |
EE200100645A (et) | Amüloidogeense haiguse preventsioon ja ravi | |
ATE334668T1 (de) | Pharmazeutische zusammensetzung zur behandlung von neurologischen und neuropsychiatrischen erkrankungen | |
ATE492525T1 (de) | Phenyl-benzyl-ketone | |
DE69716810T2 (de) | 2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one | |
NO20032801L (no) | Tiazolderivater for behandling av PPAR-relaterte forstyrrelser | |
UA27911C2 (uk) | Засіб для лікування або запобігання фізіологічних розладів, які викликані надлишком тахікініну | |
FI914723A0 (fi) | 17b-substituerade 4-aza-5a-androstan -3-jon-derivat och foerfarande foer framstaellning av desamma. | |
BR9804027A (pt) | Novos beta-ceto ésteres | |
DE69130586T2 (de) | Behandlung von Pankreaskrankheit mit 15-keto-Prostaglandin E-Derivaten | |
FI962685A (fi) | 2,3-diaryyli-1-bentsopyraanijohdannaisten käyttö lääkkeen valmistamiseksi luukadon ja osteoporoosin hoitamiseksi ja estämiseksi | |
DK376188D0 (da) | Farmaceutisk dosisenhed | |
ES2177024T3 (es) | Empleo de la fanquinoma para el tratamiento de la enfermedaad de alzheimer. | |
DE69418744T2 (de) | Verwendung von Pregnanderivaten zur Behandlung von Tumoren | |
DE69917005D1 (de) | Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung | |
ID24978A (id) | 2-ARYL-3-AROYLBENZO (b) THIOPHENES BERGUNA UNTUK PENGOBATAN SINDROM DEPRIVASI ESTROGEN | |
ES2085898T3 (es) | Tratamiento de la enfermedad hepatobiliar con compuestos 15-cetoprostaglandina. | |
FI952420A0 (fi) | Glukopyranosidibentsotiofeenit | |
ID25478A (id) | Agonis 5-ht1f | |
ATE470671T1 (de) | Verbindungen mit wachstumshormon-freisetzender eigenschaft | |
ES2150418T3 (es) | Composiciones farmaceuticas que comprenden calcitonina. | |
PT821955E (pt) | Uso de 3-(4-hexiloxi-1,2,5-tiadiazol-3-il)-1,2,5,6-tetrahidro-1-metilpiridina (xanomelina) para o tratamento da doenca bipolar | |
BR9915292A (pt) | Associação, utilização de riluzol e composição farmacêutica. | |
ID20165A (id) | Penggunaan asam 2-(3,4-dimetoksisinamoil)aminobenzoat untuk pembuatan obat untuk pengobatan atau pencegahan restenosis |