DK1129097T3 - Ny type kondenserede pyridazinonforbindelser - Google Patents
Ny type kondenserede pyridazinonforbindelserInfo
- Publication number
- DK1129097T3 DK1129097T3 DK99971809T DK99971809T DK1129097T3 DK 1129097 T3 DK1129097 T3 DK 1129097T3 DK 99971809 T DK99971809 T DK 99971809T DK 99971809 T DK99971809 T DK 99971809T DK 1129097 T3 DK1129097 T3 DK 1129097T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- stands
- formula
- alkyl
- hydrogen
- Prior art date
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- DJFWTWULJOZOGK-UHFFFAOYSA-N 3h-pyridazino[4,5-f][1,4]oxazepin-2-one Chemical compound O1C(=O)CN=CC2=CN=NC=C21 DJFWTWULJOZOGK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- DHZYXWMZLAKTQV-UHFFFAOYSA-N diazepin-3-one Chemical class O=C1C=CC=CN=N1 DHZYXWMZLAKTQV-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000006883 memory enhancing effect Effects 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- JKCJXAVMBWFTTC-UHFFFAOYSA-N thiazepine 1-oxide Chemical compound O=S1C=CC=CC=N1 JKCJXAVMBWFTTC-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9802585A HUP9802585A3 (en) | 1998-11-09 | 1998-11-09 | Pyridazinooxazepine, -thiazepine, -diazepine and thiazine derivatives and pharmaceutical compositions containing them |
| PCT/HU1999/000077 WO2000027851A1 (en) | 1998-11-09 | 1999-11-09 | Novel type condensed pyridazinone compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1129097T3 true DK1129097T3 (da) | 2003-06-02 |
Family
ID=89997316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99971809T DK1129097T3 (da) | 1998-11-09 | 1999-11-09 | Ny type kondenserede pyridazinonforbindelser |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1129097B1 (ja) |
| JP (1) | JP2002529470A (ja) |
| KR (1) | KR100636515B1 (ja) |
| AT (1) | ATE231873T1 (ja) |
| AU (1) | AU762526B2 (ja) |
| CA (1) | CA2350560C (ja) |
| DE (1) | DE69905191T2 (ja) |
| DK (1) | DK1129097T3 (ja) |
| ES (1) | ES2192104T3 (ja) |
| HU (1) | HUP9802585A3 (ja) |
| PT (1) | PT1129097E (ja) |
| WO (1) | WO2000027851A1 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0405034D0 (en) * | 2004-03-05 | 2004-04-07 | Novartis Ag | Organic compounds |
| MX2011000866A (es) | 2008-07-23 | 2011-05-25 | Health | Inhibidores del canal de aniones de superficie plasmodial como antipaludicos. |
| EP2696873B1 (en) | 2011-04-12 | 2022-08-03 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9411955D0 (en) * | 1994-06-15 | 1994-08-03 | Merck Sharp & Dohme | Therapeutic agents |
-
1998
- 1998-11-09 HU HU9802585A patent/HUP9802585A3/hu unknown
-
1999
- 1999-11-09 ES ES99971809T patent/ES2192104T3/es not_active Expired - Lifetime
- 1999-11-09 AU AU14016/00A patent/AU762526B2/en not_active Ceased
- 1999-11-09 AT AT99971809T patent/ATE231873T1/de not_active IP Right Cessation
- 1999-11-09 PT PT99971809T patent/PT1129097E/pt unknown
- 1999-11-09 KR KR1020017005304A patent/KR100636515B1/ko not_active IP Right Cessation
- 1999-11-09 EP EP99971809A patent/EP1129097B1/en not_active Expired - Lifetime
- 1999-11-09 CA CA002350560A patent/CA2350560C/en not_active Expired - Fee Related
- 1999-11-09 DE DE69905191T patent/DE69905191T2/de not_active Expired - Fee Related
- 1999-11-09 WO PCT/HU1999/000077 patent/WO2000027851A1/en active IP Right Grant
- 1999-11-09 JP JP2000581029A patent/JP2002529470A/ja active Pending
- 1999-11-09 DK DK99971809T patent/DK1129097T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002529470A (ja) | 2002-09-10 |
| HUP9802585A3 (en) | 2000-09-28 |
| DE69905191T2 (de) | 2003-10-16 |
| KR100636515B1 (ko) | 2006-10-18 |
| KR20010092424A (ko) | 2001-10-24 |
| AU762526B2 (en) | 2003-06-26 |
| HUP9802585A2 (hu) | 2000-08-28 |
| CA2350560A1 (en) | 2000-05-18 |
| DE69905191D1 (de) | 2003-03-06 |
| AU1401600A (en) | 2000-05-29 |
| WO2000027851A1 (en) | 2000-05-18 |
| ES2192104T3 (es) | 2003-09-16 |
| PT1129097E (pt) | 2003-06-30 |
| EP1129097B1 (en) | 2003-01-29 |
| HU9802585D0 (en) | 1999-01-28 |
| EP1129097A1 (en) | 2001-09-05 |
| CA2350560C (en) | 2006-10-31 |
| ATE231873T1 (de) | 2003-02-15 |
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