DK1117676T3 - Propanolaminderivater bundet til galdesyrer til behandling af forstyrrelser i lipidstofskiftet - Google Patents
Propanolaminderivater bundet til galdesyrer til behandling af forstyrrelser i lipidstofskiftetInfo
- Publication number
- DK1117676T3 DK1117676T3 DK99947385T DK99947385T DK1117676T3 DK 1117676 T3 DK1117676 T3 DK 1117676T3 DK 99947385 T DK99947385 T DK 99947385T DK 99947385 T DK99947385 T DK 99947385T DK 1117676 T3 DK1117676 T3 DK 1117676T3
- Authority
- DK
- Denmark
- Prior art keywords
- lipid metabolism
- bile acids
- treat disorders
- derivatives bound
- propanolamine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19845403A DE19845403B4 (de) | 1998-10-02 | 1998-10-02 | Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
EP99947385A EP1117676B1 (de) | 1998-10-02 | 1999-09-18 | Mit gallensäuren verknüpfte propanolaminderivate zur behandlung von lipidstoffwechselstörungen |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1117676T3 true DK1117676T3 (da) | 2004-12-20 |
Family
ID=7883185
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99947385T DK1117676T3 (da) | 1998-10-02 | 1999-09-18 | Propanolaminderivater bundet til galdesyrer til behandling af forstyrrelser i lipidstofskiftet |
Country Status (22)
Country | Link |
---|---|
US (1) | US6180618B1 (pt) |
EP (1) | EP1117676B1 (pt) |
JP (1) | JP4598953B2 (pt) |
KR (1) | KR20010075511A (pt) |
CN (1) | CN1227259C (pt) |
AR (1) | AR035003A1 (pt) |
AT (1) | ATE273991T1 (pt) |
AU (1) | AU757366B2 (pt) |
BR (1) | BR9915019A (pt) |
CA (1) | CA2346085A1 (pt) |
DE (2) | DE19845403B4 (pt) |
DK (1) | DK1117676T3 (pt) |
ES (1) | ES2226440T3 (pt) |
HK (1) | HK1040717A1 (pt) |
HU (1) | HUP0103570A3 (pt) |
ID (1) | ID29353A (pt) |
PL (1) | PL347106A1 (pt) |
PT (1) | PT1117676E (pt) |
RU (1) | RU2234512C2 (pt) |
TR (1) | TR200100897T2 (pt) |
WO (1) | WO2000020437A1 (pt) |
ZA (1) | ZA200102586B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7053076B2 (en) | 2001-08-29 | 2006-05-30 | Xenoport, Inc. | Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs |
US7161008B2 (en) * | 2002-05-03 | 2007-01-09 | Sanofi - Aventis Deutschland GmbH | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
GB0817969D0 (en) * | 2008-10-01 | 2008-11-05 | Axcess Ltd | Pharmaceutical composition |
EP2575821B1 (en) | 2010-05-26 | 2015-08-12 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
MX369466B (es) | 2011-10-28 | 2019-11-08 | Lumena Pharmaceuticals Inc | Inhibidores de la recirculación de ácidos biliares para el tratamiento de enfermedades hepáticas colestásicas pediátricas. |
KR20190135545A (ko) | 2011-10-28 | 2019-12-06 | 루메나 파마수티컬즈, 인코포레이티드 | 고담혈증 및 담즙 정체성 간 질환 치료용 담즙산 재순환 억제제 |
JP2016514684A (ja) | 2013-03-15 | 2016-05-23 | ルメナ ファーマシューティカルズ エルエルシー | 原発性硬化性胆管炎および炎症性腸疾患の処置のための胆汁酸再循環阻害剤 |
MX2015013196A (es) | 2013-03-15 | 2016-04-15 | Lumena Pharmaceuticals Inc | Inhibidores de reciclaje de acidos biliares para el tratamiento de la enfermedad de reflujo gastroesofagico y esofago de barrett. |
KR20210137046A (ko) | 2019-02-12 | 2021-11-17 | 미룸 파마슈티컬스, 인크. | 담즙정체의 치료 방법 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI892341A (fi) * | 1988-06-10 | 1989-12-11 | Hoffmann La Roche | Propanolaminderivat. |
GB2250634A (en) * | 1990-12-04 | 1992-06-10 | Marconi Gec Ltd | Point contact diodes |
US5250524A (en) * | 1990-12-06 | 1993-10-05 | Hoechst Aktiengesellschaft | Bile acid derivatives, process for their preparation and use of these compounds as pharmaceuticals |
JP2616845B2 (ja) * | 1991-02-21 | 1997-06-04 | 清水化学株式会社 | システノール酸又はその胆汁酸抱合体を含有する血中コレステロール低下剤 |
GB9203347D0 (en) * | 1992-02-17 | 1992-04-01 | Wellcome Found | Hypolipidaemic compounds |
DK0557879T3 (da) * | 1992-02-22 | 1997-06-16 | Hoechst Ag | 4-amino-2-ureido-pyrimidin-5-carboxylsyreamider, fremgangsmåde til deres fremstilling, lægemidler med indhold af disse forbindelser og deres anvendelse |
EP0624593A3 (de) * | 1993-05-08 | 1995-06-07 | Hoechst Ag | Gallensäurederivate, Verfahren zu ihrer Herstellung und Verwendung dieser Verbindungen als Arzneimittel. |
TW289021B (pt) * | 1993-05-08 | 1996-10-21 | Hoechst Ag | |
ATE268758T1 (de) * | 1997-04-04 | 2004-06-15 | Aventis Pharma Gmbh | Hypolipidämische propanolaminderivate |
-
1998
- 1998-10-02 DE DE19845403A patent/DE19845403B4/de not_active Expired - Fee Related
-
1999
- 1999-09-18 RU RU2001111816/04A patent/RU2234512C2/ru not_active IP Right Cessation
- 1999-09-18 PT PT99947385T patent/PT1117676E/pt unknown
- 1999-09-18 HU HU0103570A patent/HUP0103570A3/hu unknown
- 1999-09-18 BR BR9915019-0A patent/BR9915019A/pt not_active IP Right Cessation
- 1999-09-18 KR KR1020017004131A patent/KR20010075511A/ko not_active Application Discontinuation
- 1999-09-18 TR TR2001/00897T patent/TR200100897T2/xx unknown
- 1999-09-18 PL PL99347106A patent/PL347106A1/xx unknown
- 1999-09-18 DK DK99947385T patent/DK1117676T3/da active
- 1999-09-18 EP EP99947385A patent/EP1117676B1/de not_active Expired - Lifetime
- 1999-09-18 DE DE59910300T patent/DE59910300D1/de not_active Expired - Lifetime
- 1999-09-18 CN CNB998116343A patent/CN1227259C/zh not_active Expired - Fee Related
- 1999-09-18 JP JP2000574548A patent/JP4598953B2/ja not_active Expired - Fee Related
- 1999-09-18 CA CA002346085A patent/CA2346085A1/en not_active Abandoned
- 1999-09-18 ID IDW20010737A patent/ID29353A/id unknown
- 1999-09-18 ES ES99947385T patent/ES2226440T3/es not_active Expired - Lifetime
- 1999-09-18 AU AU60855/99A patent/AU757366B2/en not_active Ceased
- 1999-09-18 AT AT99947385T patent/ATE273991T1/de not_active IP Right Cessation
- 1999-09-18 WO PCT/EP1999/006930 patent/WO2000020437A1/de not_active Application Discontinuation
- 1999-09-29 US US09/408,169 patent/US6180618B1/en not_active Expired - Lifetime
- 1999-09-30 AR ARP990104961A patent/AR035003A1/es unknown
-
2001
- 2001-03-29 ZA ZA200102586A patent/ZA200102586B/en unknown
-
2002
- 2002-03-27 HK HK02102338.5A patent/HK1040717A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AR035003A1 (es) | 2004-04-14 |
HK1040717A1 (zh) | 2002-06-21 |
KR20010075511A (ko) | 2001-08-09 |
BR9915019A (pt) | 2001-08-14 |
WO2000020437A1 (de) | 2000-04-13 |
CN1227259C (zh) | 2005-11-16 |
TR200100897T2 (tr) | 2001-10-22 |
PL347106A1 (en) | 2002-03-25 |
DE19845403B4 (de) | 2005-02-10 |
EP1117676A1 (de) | 2001-07-25 |
AU757366B2 (en) | 2003-02-20 |
DE59910300D1 (de) | 2004-09-23 |
ATE273991T1 (de) | 2004-09-15 |
ID29353A (id) | 2001-08-23 |
ES2226440T3 (es) | 2005-03-16 |
US6180618B1 (en) | 2001-01-30 |
JP4598953B2 (ja) | 2010-12-15 |
JP2002526550A (ja) | 2002-08-20 |
HUP0103570A2 (hu) | 2002-02-28 |
HUP0103570A3 (en) | 2003-01-28 |
PT1117676E (pt) | 2004-11-30 |
EP1117676B1 (de) | 2004-08-18 |
CA2346085A1 (en) | 2000-04-13 |
CN1321166A (zh) | 2001-11-07 |
ZA200102586B (en) | 2001-10-03 |
RU2234512C2 (ru) | 2004-08-20 |
DE19845403A1 (de) | 2000-04-13 |
AU6085599A (en) | 2000-04-26 |
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