IT1293067B1 - Composizione farmaceutica per il trattamento di patologie causate da alterato metabolismo lipidico - Google Patents

Composizione farmaceutica per il trattamento di patologie causate da alterato metabolismo lipidico

Info

Publication number
IT1293067B1
IT1293067B1 IT97RM000390A ITRM970390A IT1293067B1 IT 1293067 B1 IT1293067 B1 IT 1293067B1 IT 97RM000390 A IT97RM000390 A IT 97RM000390A IT RM970390 A ITRM970390 A IT RM970390A IT 1293067 B1 IT1293067 B1 IT 1293067B1
Authority
IT
Italy
Prior art keywords
treatment
pharmaceutical composition
lipid metabolism
pathologies caused
altered lipid
Prior art date
Application number
IT97RM000390A
Other languages
English (en)
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM970390A0 publication Critical patent/ITRM970390A0/it
Priority to IT97RM000390A priority Critical patent/IT1293067B1/it
Priority to EP05105620A priority patent/EP1623708A3/en
Priority to JP50684499A priority patent/JP2002507223A/ja
Priority to PCT/IT1998/000163 priority patent/WO1999001126A1/en
Priority to NZ501844A priority patent/NZ501844A/en
Priority to AU79310/98A priority patent/AU726822B2/en
Priority to IL13349298A priority patent/IL133492A/en
Priority to US09/446,806 priority patent/US6180680B1/en
Priority to KR10-1999-7012633A priority patent/KR100539066B1/ko
Priority to CA002295748A priority patent/CA2295748A1/en
Priority to EP98929631A priority patent/EP0983066A1/en
Publication of ITRM970390A1 publication Critical patent/ITRM970390A1/it
Application granted granted Critical
Publication of IT1293067B1 publication Critical patent/IT1293067B1/it
Priority to US10/928,156 priority patent/US20050026846A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT97RM000390A 1997-01-07 1997-07-01 Composizione farmaceutica per il trattamento di patologie causate da alterato metabolismo lipidico IT1293067B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT97RM000390A IT1293067B1 (it) 1997-07-01 1997-07-01 Composizione farmaceutica per il trattamento di patologie causate da alterato metabolismo lipidico
IL13349298A IL133492A (en) 1997-07-01 1998-06-18 Pharmaceutical preparations containing alkanol L - carnitine in combination with a statin for the treatment of diseases caused by a change in lipid metabolism
KR10-1999-7012633A KR100539066B1 (ko) 1997-07-01 1998-06-18 비정상적 지질대사-유래 질환치료에 유용한 스타틴과알카노일 ｌ-카르니틴 함유 약제 조성물
PCT/IT1998/000163 WO1999001126A1 (en) 1997-07-01 1998-06-18 Pharmaceutical compositions comprising alkanoyl l-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
NZ501844A NZ501844A (en) 1997-07-01 1998-06-18 Alkanoyl L-carnitine in combination with a statin (simvastatin, lovastatin, provastatin or fluvastatin) for treating abnormal lipid metabolism disorders
AU79310/98A AU726822B2 (en) 1997-07-01 1998-06-18 Pharmaceutical compositions comprising alkanoyl L-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
EP05105620A EP1623708A3 (en) 1997-07-01 1998-06-18 Pharmaceutical composition comprising acetyl L-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
US09/446,806 US6180680B1 (en) 1997-07-01 1998-06-18 Pharmaceutical compositions comprising alkanoyl L-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
JP50684499A JP2002507223A (ja) 1997-07-01 1998-06-18 脂質代謝異常によりもたらされる疾患の治療のための、アルカノイルｌ−カルニチンをスタチンと組み合わせて含む医薬組成物
CA002295748A CA2295748A1 (en) 1997-07-01 1998-06-18 Pharmaceutical compositions comprising alkanoyl l-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
EP98929631A EP0983066A1 (en) 1997-07-01 1998-06-18 Pharmaceutical composition comprising alkanoyl l-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
US10/928,156 US20050026846A1 (en) 1997-01-07 2004-08-30 Pharmaceutical compositions comprising alkanoyl L-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000390A IT1293067B1 (it) 1997-07-01 1997-07-01 Composizione farmaceutica per il trattamento di patologie causate da alterato metabolismo lipidico

Publications (3)

Publication Number Publication Date
ITRM970390A0 ITRM970390A0 (it) 1997-07-01
ITRM970390A1 ITRM970390A1 (it) 1999-01-01
IT1293067B1 true IT1293067B1 (it) 1999-02-11

Family

ID=11405149

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97RM000390A IT1293067B1 (it) 1997-01-07 1997-07-01 Composizione farmaceutica per il trattamento di patologie causate da alterato metabolismo lipidico

Country Status (10)

Country Link
US (2) US6180680B1 (it)
EP (2) EP1623708A3 (it)
JP (1) JP2002507223A (it)
KR (1) KR100539066B1 (it)
AU (1) AU726822B2 (it)
CA (1) CA2295748A1 (it)
IL (1) IL133492A (it)
IT (1) IT1293067B1 (it)
NZ (1) NZ501844A (it)
WO (1) WO1999001126A1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100725263B1 (ko) * 1999-06-08 2007-06-07 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. ＨＭＧ-ＣｏＡ 리덕타제 억제제 및 카르니틴을 포함하는 항지질혈성 복합제
US6245800B1 (en) * 1999-06-08 2001-06-12 Sigma-Tau Method of preventing or treating statin-induced toxic effects using L-carnitine or an alkanoyl L-carnitine
ES2237073T3 (es) * 1999-06-30 2005-07-16 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Combinacion con actividad hipolipemiante sustancialmente exenta de efectos toxicos o secundarios inducidos por farmacos hipolimiantes.
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
ITRM20040307A1 (it) 2004-06-23 2004-09-23 Sigma Tau Ind Farmaceuti Confezione per almeno due prodotti differenti da vendere e utilizzare insieme.
US20100029759A1 (en) * 2007-02-27 2010-02-04 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composition useful for the treatment of type 2 diabetes
CN101663030B (zh) 2007-03-21 2013-08-21 希格马托制药工业公司 可用于预防患有胰岛素耐受的前驱糖尿病患者的2型糖尿病及其并发症的组合物
HUE042168T2 (hu) * 2008-02-29 2019-06-28 Biolab Sanus Farmaceutica Ltda Racetámot és karnitint tartalmazó gyógyszerkészítmény és eljárás elõállítására
US11591288B2 (en) 2017-08-23 2023-02-28 Gavish-Galilee Bio Applications Ltd. Compositions and methods for treating atherosclerotic cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2903579A1 (de) * 1978-02-03 1979-08-09 Sigma Tau Ind Farmaceuti Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel

Also Published As

Publication number Publication date
KR20010014439A (ko) 2001-02-26
US6180680B1 (en) 2001-01-30
KR100539066B1 (ko) 2005-12-26
WO1999001126A1 (en) 1999-01-14
JP2002507223A (ja) 2002-03-05
ITRM970390A0 (it) 1997-07-01
NZ501844A (en) 2001-10-26
ITRM970390A1 (it) 1999-01-01
IL133492A0 (en) 2001-04-30
EP1623708A3 (en) 2006-02-15
AU7931098A (en) 1999-01-25
US20050026846A1 (en) 2005-02-03
EP0983066A1 (en) 2000-03-08
AU726822B2 (en) 2000-11-23
CA2295748A1 (en) 1999-01-14
EP1623708A2 (en) 2006-02-08
IL133492A (en) 2004-07-25

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