DK1115687T3 - 5,6-Dihydronaphthalenylderivater med retinoid-lignende aktivitet - Google Patents

5,6-Dihydronaphthalenylderivater med retinoid-lignende aktivitet

Info

Publication number
DK1115687T3
DK1115687T3 DK99948322T DK99948322T DK1115687T3 DK 1115687 T3 DK1115687 T3 DK 1115687T3 DK 99948322 T DK99948322 T DK 99948322T DK 99948322 T DK99948322 T DK 99948322T DK 1115687 T3 DK1115687 T3 DK 1115687T3
Authority
DK
Denmark
Prior art keywords
dihydronaphthalenyl
derivatives
retinoid
activity
formulaepossess
Prior art date
Application number
DK99948322T
Other languages
Danish (da)
English (en)
Inventor
Anne Marinier
Yong-Jiang Hei
Philippe Lapointe
Jean-Paul Daris
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DK1115687T3 publication Critical patent/DK1115687T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/66Polycyclic acids with unsaturation outside the aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/19Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
DK99948322T 1998-09-24 1999-09-16 5,6-Dihydronaphthalenylderivater med retinoid-lignende aktivitet DK1115687T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10160998P 1998-09-24 1998-09-24

Publications (1)

Publication Number Publication Date
DK1115687T3 true DK1115687T3 (da) 2004-09-20

Family

ID=22285543

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99948322T DK1115687T3 (da) 1998-09-24 1999-09-16 5,6-Dihydronaphthalenylderivater med retinoid-lignende aktivitet

Country Status (14)

Country Link
US (1) US6194601B1 (ja)
EP (1) EP1115687B1 (ja)
JP (1) JP2002526465A (ja)
CN (1) CN1134405C (ja)
AT (1) ATE267793T1 (ja)
AU (1) AU761572B2 (ja)
BR (1) BR9913925A (ja)
CA (1) CA2344310A1 (ja)
DE (1) DE69917660T2 (ja)
DK (1) DK1115687T3 (ja)
ES (1) ES2221754T3 (ja)
PT (1) PT1115687E (ja)
TR (1) TR200100858T2 (ja)
WO (1) WO2000017147A1 (ja)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780676A (en) * 1992-04-22 1998-07-14 Ligand Pharmaceuticals Incorporated Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors
US5648385A (en) * 1994-01-03 1997-07-15 Bristol-Myers Squibb Co. Retinoid-like compounds
US5618943A (en) * 1994-12-29 1997-04-08 Allergan Acetylenes disubstituted with a 5 OXO substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5648514A (en) 1994-12-29 1997-07-15 Allergan Substituted acetylenes having retinoid-like biological activity
US5489584A (en) * 1994-12-29 1996-02-06 Allergan, Inc. Acetylenes disubstituted with a 5-amino or substituted 5-amino substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5514825A (en) * 1994-12-29 1996-05-07 Allergan, Inc. Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity
US5599967A (en) * 1994-12-29 1997-02-04 Allergan Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl of heteroaryl group having retinoid-like biological activity
US5543534A (en) * 1994-12-29 1996-08-06 Allergan Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity
EP0915825B1 (en) * 1996-06-21 2004-05-06 Allergan, Inc. Substituted tetrahydronaphthalene and dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity

Also Published As

Publication number Publication date
TR200100858T2 (tr) 2001-10-22
DE69917660D1 (de) 2004-07-01
AU6152899A (en) 2000-04-10
JP2002526465A (ja) 2002-08-20
BR9913925A (pt) 2001-06-19
DE69917660T2 (de) 2005-06-16
CN1319083A (zh) 2001-10-24
WO2000017147A1 (en) 2000-03-30
EP1115687B1 (en) 2004-05-26
AU761572B2 (en) 2003-06-05
EP1115687A4 (en) 2002-06-05
CN1134405C (zh) 2004-01-14
US6194601B1 (en) 2001-02-27
EP1115687A1 (en) 2001-07-18
ATE267793T1 (de) 2004-06-15
PT1115687E (pt) 2004-09-30
ES2221754T3 (es) 2005-01-01
CA2344310A1 (en) 2000-03-30

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