DK1090039T3 - Peptidsammensætning som immunogen til behandling af allergi - Google Patents

Peptidsammensætning som immunogen til behandling af allergi

Info

Publication number
DK1090039T3
DK1090039T3 DK99928818T DK99928818T DK1090039T3 DK 1090039 T3 DK1090039 T3 DK 1090039T3 DK 99928818 T DK99928818 T DK 99928818T DK 99928818 T DK99928818 T DK 99928818T DK 1090039 T3 DK1090039 T3 DK 1090039T3
Authority
DK
Denmark
Prior art keywords
ige
peptides
immunogen
allergy
treatment
Prior art date
Application number
DK99928818T
Other languages
Danish (da)
English (en)
Inventor
Chang Yi Wang
Alan M Walfield
Original Assignee
United Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United Biomedical Inc filed Critical United Biomedical Inc
Application granted granted Critical
Publication of DK1090039T3 publication Critical patent/DK1090039T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99928818T 1998-06-20 1999-06-21 Peptidsammensætning som immunogen til behandling af allergi DK1090039T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10028798A 1998-06-20 1998-06-20
PCT/US1999/013959 WO1999067293A1 (en) 1998-06-20 1999-06-21 Peptide composition as immunogen for the treatment of allergy

Publications (1)

Publication Number Publication Date
DK1090039T3 true DK1090039T3 (da) 2009-07-27

Family

ID=22279023

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99928818T DK1090039T3 (da) 1998-06-20 1999-06-21 Peptidsammensætning som immunogen til behandling af allergi

Country Status (14)

Country Link
US (2) US6811782B1 (zh)
EP (1) EP1090039B1 (zh)
JP (1) JP4031201B2 (zh)
CN (1) CN1259340C (zh)
AT (1) ATE429448T1 (zh)
AU (1) AU757919B2 (zh)
BR (1) BRPI9911389B8 (zh)
CA (1) CA2329754C (zh)
DE (1) DE69940775D1 (zh)
DK (1) DK1090039T3 (zh)
HK (1) HK1036804A1 (zh)
TW (1) TWI227241B (zh)
WO (1) WO1999067293A1 (zh)
ZA (1) ZA200006384B (zh)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393529B2 (en) * 1998-04-09 2008-07-01 Idexx Laboratories, Inc. Methods and compositions for inhibiting binding of IgE to a high affinity receptor
US6504013B1 (en) 2000-02-01 2003-01-07 Idexx Laboratories, Inc. Canine allergy therapeutic recombinant chimeric anti-IgE monoclonal antibody
TWI227241B (en) * 1998-06-20 2005-02-01 United Biomedical Inc IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate
TWI229679B (en) * 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens
US6913749B2 (en) 1998-11-02 2005-07-05 Resistentia Pharmaceuticals Ab Immunogenic polypeptides for inducing anti-self IgE responses
DK1135162T3 (da) 1998-11-30 2009-01-19 Cytos Biotechnology Ag Ordnet molekylær præsentation af allergener, fremstillingsfremgangsmåde samt anvendelse
HUP0105490A3 (en) * 1999-02-25 2002-05-28 Peptide Therapeutics Ltd Cambr Epitopes or mimotopes derived from the c-epsilon-3 or c-epsilon-4 domains of ige, antagonists thereof, and their therapeutic uses
HUP0301085A3 (en) * 2000-01-14 2005-06-28 Daiichi Seiyaku Co Novel peptide and screening method by using the same
WO2001085208A2 (en) 2000-05-05 2001-11-15 Cytos Biotechnology Ag Molecular antigen arrays and vaccines
GB0020717D0 (en) * 2000-08-22 2000-10-11 Smithkline Beecham Biolog Novel compounds and process
EP1967206B1 (en) * 2000-08-30 2012-10-10 Pfizer Products Inc. Anti-IgE vaccines
GB0026334D0 (en) * 2000-10-27 2000-12-13 Smithkline Beecham Biolog Vaccine
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7264810B2 (en) 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
US7265208B2 (en) 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
CA2447593C (en) * 2001-05-15 2014-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ex-vivo priming for generating cytotoxic t lymphocytes specific for non-tumor antigens to treat autoimmune and allergic disease
JP2003047482A (ja) 2001-05-22 2003-02-18 Pfizer Prod Inc 非アナフィラキシー誘発性ＩｇＥワクチン
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
US8088388B2 (en) 2002-02-14 2012-01-03 United Biomedical, Inc. Stabilized synthetic immunogen delivery system
IL165372A0 (en) * 2002-06-11 2006-01-15 Glaxosmithkline Biolog Immunodenic compositions
AU2003243663A1 (en) 2002-06-20 2004-01-06 The Trustees Of The University Of Pennsylvania Vaccines for suppressing ige-mediated allergic disease and methods for using the same
CN102061288A (zh) 2002-07-17 2011-05-18 希托斯生物技术股份公司 使用衍生自ap205外壳蛋白的病毒样颗粒的分子抗原阵列
IL165249A0 (en) 2002-07-18 2005-12-18 Cytos Biotechnology Ag Hapten-carrier conjugates and uses thereof
EP1524994B1 (en) 2002-07-19 2011-04-27 Cytos Biotechnology AG Vaccine compositions containing amyloid beta1-6 antigen arrays
ATE519784T1 (de) 2003-11-26 2011-08-15 Max Planck Gesellschaft An den humanen igg-fc-rezeptor iib (fcgammariib) bindende substanz
KR101581659B1 (ko) * 2004-02-02 2015-12-31 타녹스 인코퍼레이티드 신규한 ＩｇＥ 에피토프의 확인
WO2007032804A2 (en) 2005-06-30 2007-03-22 Clifford Risk Novel uses for anti-ige therapy
US7534595B2 (en) * 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
EP2126067B1 (en) * 2007-02-23 2014-07-02 Landing Biotech, Inc. Treating atherosclerosis
EP2012122A1 (en) 2007-07-06 2009-01-07 Medigene AG Mutated parvovirus structural proteins as vaccines
US8865179B2 (en) * 2008-01-26 2014-10-21 Swey-Shen Alexchen Aptameric IgE peptides in a protein scaffold as an allergy vaccine
AU2013204233B2 (en) * 2008-12-09 2015-06-25 Pfizer Vaccines Llc IgE CH3 peptide vaccine
KR101644221B1 (ko) 2008-12-09 2016-07-29 화이자 백신스 엘엘씨 ＩｇＥ ＣＨ３ 펩티드 백신
MY163512A (en) * 2009-09-03 2017-09-15 Pfizer Vaccines Llc Pcsk9 vaccine
WO2011154878A1 (en) * 2010-06-07 2011-12-15 Pfizer Vaccines Llc Ige ch3 peptide vaccine
US9187553B2 (en) * 2012-01-25 2015-11-17 Swey-Shen Chen Displaying native human IgE neutralizing FcepsilonRIa-contacting IgE B-cell epitopes by constraining super beta(b)-strands and cystine knots on thermostable protein scaffold
US9657071B2 (en) * 2012-06-18 2017-05-23 Nippon Zenyaku Kogyo Co., Ltd. IgE peptide vaccine
CN104558196A (zh) * 2013-10-15 2015-04-29 温州医科大学 基于HBcAg载体的沙眼衣原体主要外膜蛋白表位疫苗及其用途
US20170216418A1 (en) * 2014-07-25 2017-08-03 United Biomedical, Inc. Immunogenic lhrh composition and use thereof in pigs
CN109863165A (zh) * 2016-08-23 2019-06-07 爱姆维恩公司 新型免疫刺激肽
RU2769983C2 (ru) * 2017-12-31 2022-04-12 Юнайтед Байомедикал, Инк. ПЕПТИДНЫЕ ИММУНОГЕНЫ И СОДЕРЖАЩИЕ ИХ СОСТАВЫ, НАЦЕЛЕННЫЕ НА МЕМБРАНОСВЯЗАННЫЕ IgE ДЛЯ ЛЕЧЕНИЯ ОПОСРЕДОВАННЫХ IgE АЛЛЕРГИЧЕСКИХ ЗАБОЛЕВАНИЙ
EP4213874A1 (en) 2020-09-17 2023-07-26 Neovacs Immunogenic product comprising an ige fragment for treating ige-mediated inflammatory disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4940782A (en) 1987-06-08 1990-07-10 G. D. Searle & Co. Monoclonal antibodies against IgE-associated determinants, hybrid cell lines producing these antibodies, and use therefore
US5449760A (en) 1987-12-31 1995-09-12 Tanox Biosystems, Inc. Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils
DE69232944T2 (de) 1991-08-14 2003-12-24 Genentech, Inc. Veränderte Immunglobuline für spezifische FC-Epsilon Rezeptoren
CA2161445C (en) 1993-04-27 2009-06-30 Anna Efim Ladd Immunogenic lhrh peptide constructs and synthetic universal immune stimulators for vaccines
WO1995026365A1 (en) * 1994-03-28 1995-10-05 United Biomedical, Inc. Synthetic peptide based immunogens for the treatment of allergy
JPH09169795A (ja) 1995-12-22 1997-06-30 Hitachi Chem Co Ltd イヌ免疫グロブリンｅペプチド断片、それをコードするｄｎａ、そのｄｎａを含む組換えベクター、その組換えベクターを含む形質転換体及び抗イヌ免疫グロブリンｅ抗体の製造法
WO1998024808A2 (en) 1996-12-06 1998-06-11 THE UNITED STATES OF AMERICA represented by THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH INHIBITION OF IgE-MEDIATED ALLERGIES BY A HUMAN IgE-DERIVED OLIGOPEPTIDE
TWI229679B (en) * 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens
TWI227241B (en) * 1998-06-20 2005-02-01 United Biomedical Inc IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate
US6025468A (en) * 1998-06-20 2000-02-15 United Biomedical, Inc. Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens including immunogenic LHRH peptides

Also Published As

Publication number Publication date
BRPI9911389B1 (pt) 2018-03-20
US20050250934A1 (en) 2005-11-10
AU757919B2 (en) 2003-03-13
ATE429448T1 (de) 2009-05-15
TWI227241B (en) 2005-02-01
ZA200006384B (en) 2001-05-29
EP1090039B1 (en) 2009-04-22
EP1090039A4 (en) 2002-08-07
BRPI9911389B8 (pt) 2021-05-25
US6811782B1 (en) 2004-11-02
CN1305498A (zh) 2001-07-25
AU4580299A (en) 2000-01-10
EP1090039A1 (en) 2001-04-11
CA2329754A1 (en) 1999-12-29
JP4031201B2 (ja) 2008-01-09
BR9911389A (pt) 2001-03-20
JP2002518038A (ja) 2002-06-25
CA2329754C (en) 2011-12-20
DE69940775D1 (de) 2009-06-04
US7648701B2 (en) 2010-01-19
WO1999067293A1 (en) 1999-12-29
HK1036804A1 (en) 2002-01-18
CN1259340C (zh) 2006-06-14

Similar Documents

Publication Publication Date Title
DK1090039T3 (da) Peptidsammensætning som immunogen til behandling af allergi
DE69941625D1 (de) Antigener komplex, der ein immunstimulierendes peptid enthält, cd4 und chemokinrezeptor-domäne zur behandlung von hiv und immunerkrankungen
CY1117387T1 (el) ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ Ν-11 ΔΙΑΣΠΑΣΜΕΝΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, ΣΥΝΘΕΣΕΙΣ, ΜΕΘΟΔΟΙ ΚΑΙ ΧΡΗΣΕΙΣ
WO2003045128A3 (en) SYNTHETIC IMMUNOGENIC BUT NON-DEPOSIT-FORMING POLYPEPTIDES AND PEPTIDES HOMOLOGOUS TO AMYLOID β, PRION PROTEIN, AMYLIN, α-SYNUCLEIN, OR POLYGLUTAMINE REPEATS FOR INDUCTION OF AN IMMUNE RESPONSE THERETO
CY1107628T1 (el) Ανθρωπινα ctla-4 αντισωματα και χρησεις αυτων
CY1118443T1 (el) Anti-tnf αντισωματα, συνθεσεις, μεθοδοι και χρησεις
ATE244891T1 (de) Verfahren zur selektion und produktion von t-zell-peptide epitope und vakzine mit diese epitope
CY1109649T1 (el) Αντιγονα και συνθεσεις απο neisseria
BR0010361A (pt) Seq ências genÈmicas de neisseria e uso destas
HUP0004639A2 (hu) Chlamydia fehérje, génszekvencia és ezek alkalmazása
NO20045021L (no) Immunologiske metoder og preparater for behandling av Alzheimers sykdom
CY1113379T1 (el) Πεπτιδια κdr και εμβολια που τα περιλαμβανουν
PT1326634E (pt) Composicao de vacina compreendendo um antigenio e um peptido possuindo propriedades adjuvantes
BRPI0407058A (pt) Métodos de profilaxia e de tratamento de uma doença, composição farmacêutica, e, uso de um fragmento
CY1113243T1 (el) Μεθοδοι θεραπειας με χρηση αντισωματων cτlα-4
BR9707819A (pt) Imunogenos peptidicos
CY1108570T1 (el) Gd3-μιμητικα πεπτιδια
DE69636285D1 (de) ISOLIERTES FrpB NUKLEINSÄUREMOLEKÜL UND ENTSPRECHENDE IMPFSTOFF
DK0954529T3 (da) Porphyromonas gingivalis-antigener til diagnose og behandling af rodbetændelse
NO20011537L (no) Chemokin-reseptorpeptidvaksiner for behandling og forebygging av diabetes
DE69839943D1 (de) Verhinderung von immunreaktivität durch verarmung oder inhibition von antigen-präsentierenden zellen
ATE525470T1 (de) Antigene epitope des faktors viii, inhibitoren dagegen, und deren verwendungen
EP1377304A4 (en) NOVEL ISOFORM OF TRP2 CONTAINING CYTOTOXIC EPITOPES OF HLA-A2 RESTRICTED T CELL PYMPHOCYTE
CY1115126T1 (el) Μεθοδος και εμβολιο που περιλαμβανει συμπολυμερες 1 για θεραπεια ψυχιατρικων διαταραχων