DK1086245T3 - Multi-fluorescerende hårnål-energioverførsel-oligonukleotider - Google Patents

Multi-fluorescerende hårnål-energioverførsel-oligonukleotider

Info

Publication number
DK1086245T3
DK1086245T3 DK99928465T DK99928465T DK1086245T3 DK 1086245 T3 DK1086245 T3 DK 1086245T3 DK 99928465 T DK99928465 T DK 99928465T DK 99928465 T DK99928465 T DK 99928465T DK 1086245 T3 DK1086245 T3 DK 1086245T3
Authority
DK
Denmark
Prior art keywords
oligonucleotide
fluorophore
acceptor
donor
targets
Prior art date
Application number
DK99928465T
Other languages
Danish (da)
English (en)
Inventor
Glenn Nardone
Original Assignee
Intergen Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intergen Company filed Critical Intergen Company
Application granted granted Critical
Publication of DK1086245T3 publication Critical patent/DK1086245T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
DK99928465T 1998-06-12 1999-06-11 Multi-fluorescerende hårnål-energioverførsel-oligonukleotider DK1086245T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8911998P 1998-06-12 1998-06-12
PCT/US1999/012799 WO1999064432A2 (fr) 1998-06-12 1999-06-11 Oligonucleotides de transfert d'energie en epingle a cheveux a multifluorescence

Publications (1)

Publication Number Publication Date
DK1086245T3 true DK1086245T3 (da) 2003-11-24

Family

ID=22215796

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99928465T DK1086245T3 (da) 1998-06-12 1999-06-11 Multi-fluorescerende hårnål-energioverførsel-oligonukleotider

Country Status (9)

Country Link
EP (1) EP1086245B1 (fr)
JP (1) JP2002517506A (fr)
AT (1) ATE246256T1 (fr)
CA (1) CA2335026A1 (fr)
DE (1) DE69910026T2 (fr)
DK (1) DK1086245T3 (fr)
ES (1) ES2205841T3 (fr)
PT (1) PT1086245E (fr)
WO (1) WO1999064432A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
CN102732610B (zh) * 2012-03-23 2014-01-29 章晓联 可视化检测探针及在结核病利福平耐药突变检测中的应用
CN102628085B (zh) * 2012-04-24 2014-06-04 武汉大学 结核分枝杆菌利福平耐药突变可视化检测探针及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0566751B1 (fr) * 1992-03-23 1996-01-10 F. Hoffmann-La Roche Ag Méthode pour la détection de l'ADN
EP0601889A2 (fr) * 1992-12-10 1994-06-15 Maine Medical Center Research Institute Sondes d'acides nucléiques
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon

Also Published As

Publication number Publication date
EP1086245A2 (fr) 2001-03-28
JP2002517506A (ja) 2002-06-18
DE69910026D1 (de) 2003-09-04
CA2335026A1 (fr) 1999-12-16
ES2205841T3 (es) 2004-05-01
WO1999064432A2 (fr) 1999-12-16
PT1086245E (pt) 2003-12-31
WO1999064432A3 (fr) 2000-02-24
ATE246256T1 (de) 2003-08-15
EP1086245B1 (fr) 2003-07-30
DE69910026T2 (de) 2004-04-15

Similar Documents

Publication Publication Date Title
CA2244964A1 (fr) Detection d'acides nucleiques par extinction de fluorescence
Pianowski et al. Imaging of mRNA in live cells using nucleic acid-templated reduction of azidorhodamine probes
Seth Photoenzymic repair of UV-damaged DNA: a chemist's perspective
DE69735313D1 (de) Fluoreszenz-Donor-Akzeptor Paar
CN102782159B (zh) 将核酸进行测序之组合物与方法
US5607834A (en) Fluorescent imperfect hairpin nucleic acid probes
WO1999011813A3 (fr) Sondes oligonucleotidiques portant des marqueurs a fluorescence extinguible et leurs procedes d'utilisation
AU3728597A (en) Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
CN101268188B (zh) 新型人工碱基对及其应用
ATE414170T1 (de) Wellenlängen verschiebende proben und primer
US20200278298A1 (en) Systems and methods for genetic sequencing
WO2001016375A3 (fr) Sequençage de molecules d'acide nucleique a grande vitesseen parallele
EP1087020A3 (fr) Sondes d'acide nucléiques universelles et méthodes de détection des acides nucléiques
ES2082256T3 (es) Metodo de deteccion del adn.
Li et al. Specific nucleic acid detection based on fluorescent light-up probe from fluorogens with aggregation-induced emission characteristics
HK1047454A1 (en) Fluorescent intensity assay for duplex and triplexnucleic acid hybridization in solution utilizing fluorescent intercalators
EP0878554A3 (fr) Détection d'acids nucléiques basée sur l'extinction de la fluorescence
Feng et al. Dual-amplified sensitive DNA detection based on conjugated polymers and recyclable autocatalytic hybridization of DNA
DK1086245T3 (da) Multi-fluorescerende hårnål-energioverførsel-oligonukleotider
ES2096041T3 (es) Deteccion de secuencias nucleotidicas complementarias.
WO2010119371A1 (fr) Dispositif de détection de fluorescence temporisée
Ikeda et al. Design and synthesis of caged fluorescent nucleotides and application to live‐cell RNA imaging
Takei et al. RT‐Hpro‐PCR: a MicroRNA detection system using a primer with a DNA tag
GB9918237D0 (en) Detection system
AU2001237685A1 (en) Method and system for the simultaneous and multiple detection and quantificationof the hybridization of molecular compounds such as nucleic acids, dna, rna, pn and proteins