DE69910026D1 - Mehrfach fluoreszierende und energie übertragende hairpin-oligonukleotide - Google Patents

Mehrfach fluoreszierende und energie übertragende hairpin-oligonukleotide

Info

Publication number
DE69910026D1
DE69910026D1 DE69910026T DE69910026T DE69910026D1 DE 69910026 D1 DE69910026 D1 DE 69910026D1 DE 69910026 T DE69910026 T DE 69910026T DE 69910026 T DE69910026 T DE 69910026T DE 69910026 D1 DE69910026 D1 DE 69910026D1
Authority
DE
Germany
Prior art keywords
oligonucleotide
fluorophore
acceptor
donor
targets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69910026T
Other languages
English (en)
Other versions
DE69910026T2 (de
Inventor
Glenn Nardone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intergen Co
Original Assignee
Intergen Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intergen Co filed Critical Intergen Co
Publication of DE69910026D1 publication Critical patent/DE69910026D1/de
Application granted granted Critical
Publication of DE69910026T2 publication Critical patent/DE69910026T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
DE69910026T 1998-06-12 1999-06-11 Mehrfach fluoreszierende und energie übertragende hairpin-oligonukleotide Expired - Fee Related DE69910026T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8911998P 1998-06-12 1998-06-12
US89119P 1998-06-12
PCT/US1999/012799 WO1999064432A2 (en) 1998-06-12 1999-06-11 Multi-fluorescent hairpin energy transfer oligonucleotides

Publications (2)

Publication Number Publication Date
DE69910026D1 true DE69910026D1 (de) 2003-09-04
DE69910026T2 DE69910026T2 (de) 2004-04-15

Family

ID=22215796

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69910026T Expired - Fee Related DE69910026T2 (de) 1998-06-12 1999-06-11 Mehrfach fluoreszierende und energie übertragende hairpin-oligonukleotide

Country Status (9)

Country Link
EP (1) EP1086245B1 (de)
JP (1) JP2002517506A (de)
AT (1) ATE246256T1 (de)
CA (1) CA2335026A1 (de)
DE (1) DE69910026T2 (de)
DK (1) DK1086245T3 (de)
ES (1) ES2205841T3 (de)
PT (1) PT1086245E (de)
WO (1) WO1999064432A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037130A (en) * 1998-07-28 2000-03-14 The Public Health Institute Of The City Of New York, Inc. Wavelength-shifting probes and primers and their use in assays and kits
US9261460B2 (en) 2002-03-12 2016-02-16 Enzo Life Sciences, Inc. Real-time nucleic acid detection processes and compositions
US9353405B2 (en) 2002-03-12 2016-05-31 Enzo Life Sciences, Inc. Optimized real time nucleic acid detection processes
CN102732610B (zh) * 2012-03-23 2014-01-29 章晓联 可视化检测探针及在结核病利福平耐药突变检测中的应用
CN102628085B (zh) * 2012-04-24 2014-06-04 武汉大学 结核分枝杆菌利福平耐药突变可视化检测探针及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69207580T2 (de) * 1992-03-23 1996-08-08 Hoffmann La Roche Verfahren zum DNS-Nachweis
EP0601889A2 (de) * 1992-12-10 1994-06-15 Maine Medical Center Research Institute Nukleinsäure-Sonden
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon

Also Published As

Publication number Publication date
WO1999064432A2 (en) 1999-12-16
CA2335026A1 (en) 1999-12-16
EP1086245A2 (de) 2001-03-28
DK1086245T3 (da) 2003-11-24
DE69910026T2 (de) 2004-04-15
ES2205841T3 (es) 2004-05-01
EP1086245B1 (de) 2003-07-30
PT1086245E (pt) 2003-12-31
ATE246256T1 (de) 2003-08-15
WO1999064432A3 (en) 2000-02-24
JP2002517506A (ja) 2002-06-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee