DK108189A - Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer - Google Patents

Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer

Info

Publication number
DK108189A
DK108189A DK108189A DK108189A DK108189A DK 108189 A DK108189 A DK 108189A DK 108189 A DK108189 A DK 108189A DK 108189 A DK108189 A DK 108189A DK 108189 A DK108189 A DK 108189A
Authority
DK
Denmark
Prior art keywords
antibodies
chimerary
humant
chelates
metal
Prior art date
Application number
DK108189A
Other languages
Danish (da)
English (en)
Other versions
DK108189D0 (da
Inventor
Mary Jaqueline Johnson
Julie Lefevre Phelps
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Publication of DK108189D0 publication Critical patent/DK108189D0/da
Publication of DK108189A publication Critical patent/DK108189A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK108189A 1988-11-17 1989-03-07 Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer DK108189A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27410588A 1988-11-17 1988-11-17

Publications (2)

Publication Number Publication Date
DK108189D0 DK108189D0 (da) 1989-03-07
DK108189A true DK108189A (da) 1990-05-18

Family

ID=23046793

Family Applications (1)

Application Number Title Priority Date Filing Date
DK108189A DK108189A (da) 1988-11-17 1989-03-07 Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer

Country Status (5)

Country Link
EP (1) EP0369566A3 (xx)
JP (1) JPH02145187A (xx)
AU (1) AU618324B2 (xx)
DK (1) DK108189A (xx)
IL (1) IL89491A0 (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89489A0 (en) * 1988-03-09 1989-09-10 Hybritech Inc Chimeric antibodies directed against human carcinoembryonic antigen
IL89491A0 (en) * 1988-11-17 1989-09-10 Hybritech Inc Bifunctional chimeric antibodies
IL89490A0 (en) * 1988-11-17 1989-09-10 Hybritech Inc Chimeric antibodies directed against metal chelates
DE3920358A1 (de) * 1989-06-22 1991-01-17 Behringwerke Ag Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
CA2097060A1 (en) * 1990-12-04 1992-06-05 Peter J. Curtis Bifunctional antibodies and method of preparing same
US5582996A (en) * 1990-12-04 1996-12-10 The Wistar Institute Of Anatomy & Biology Bifunctional antibodies and method of preparing same
JPH0576385A (ja) * 1990-12-18 1993-03-30 Takeda Chem Ind Ltd キメラ抗体およびその用途
ZA938243B (en) * 1992-11-12 1995-05-04 Hybritech Inc Altered affinity polypeptides of metal chelate binding antibodies
US5532136A (en) * 1993-06-22 1996-07-02 Bionebraska, Inc. Monoclonal antibody assay and kit for detecting metal cations in body fluids
GB9819411D0 (en) * 1998-09-04 1998-10-28 Ks Biomedix Ltd Antibodies
WO2005035753A1 (ja) 2003-10-10 2005-04-21 Chugai Seiyaku Kabushiki Kaisha 機能蛋白質を代替する二重特異性抗体
EP2311945A1 (en) 2003-10-14 2011-04-20 Chugai Seiyaku Kabushiki Kaisha Bispecific antibodies substituting for functional proteins
EP1870459B1 (en) 2005-03-31 2016-06-29 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
DK2009101T3 (en) 2006-03-31 2018-01-15 Chugai Pharmaceutical Co Ltd Antibody modification method for purification of a bispecific antibody
DK2006381T3 (en) 2006-03-31 2016-02-22 Chugai Pharmaceutical Co Ltd PROCEDURE FOR REGULATING ANTIBODIES BLOOD PHARMACOKINETICS
HUE029635T2 (en) 2007-09-26 2017-03-28 Chugai Pharmaceutical Co Ltd A method for modifying an isoelectric point of an antibody by amino acid substitution in CDR
RU2620071C2 (ru) 2010-11-17 2017-05-22 Чугаи Сеияку Кабушики Каиша Мультиспецифическая связывающая антиген молекула, которая обладает альтернативной функцией к функции фактора свертывания крови viii
CA2925256C (en) 2013-09-27 2023-08-15 Chugai Seiyaku Kabushiki Kaisha Method for producing polypeptide heteromultimer
TWI700300B (zh) 2014-09-26 2020-08-01 日商中外製藥股份有限公司 中和具有第ｖｉｉｉ凝血因子（ｆｖｉｉｉ）機能替代活性的物質之抗體
MA40764A (fr) 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd Agent thérapeutique induisant une cytotoxicité
TWI701435B (zh) 2014-09-26 2020-08-11 日商中外製藥股份有限公司 測定ｆｖｉｉｉ的反應性之方法
EP3279216A4 (en) 2015-04-01 2019-06-19 Chugai Seiyaku Kabushiki Kaisha PROCESS FOR PREPARING POLYPEPTIDE HETERO OLIGOMER
EP3398965A4 (en) 2015-12-28 2019-09-18 Chugai Seiyaku Kabushiki Kaisha METHOD FOR PROMOTING THE EFFICACY OF PURIFYING A POLYPEPTIDE CONTAINING AN FC REGION
CN109661241A (zh) 2016-09-06 2019-04-19 中外制药株式会社 使用识别凝血因子ix和/或活化凝血因子ix以及凝血因子x和/或活化凝血因子x的双特异性抗体的方法
CN108220281A (zh) * 2017-09-25 2018-06-29 天津强微特生物科技有限公司 一种含有结合核酸的磁珠在生物样品保存液的制备和运用
UA128389C2 (uk) 2017-09-29 2024-07-03 Чугаі Сейяку Кабусікі Кайся Мультиспецифічна антигензв'язувальна молекула, яка має активність заміщувати кофакторну функцію фактора коагуляції крові viii (fviii), та фармацевтичний склад, який містить згадану молекулу як активний інгредієнт

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1339445C (en) * 1986-11-12 1997-09-09 The General Hospital Corporation Recombinant hybrid immunoglobulin molecules and method of use
JP2520464B2 (ja) * 1987-05-29 1996-07-31 タノツクス・バイオシステムズ・インコーポレーテツド Ｈｉｖ―１を中和するモノクロ―ナル抗体
AU625613B2 (en) * 1988-01-05 1992-07-16 Novartis Ag Novel chimeric antibodies
IL89489A0 (en) * 1988-03-09 1989-09-10 Hybritech Inc Chimeric antibodies directed against human carcinoembryonic antigen
IL89491A0 (en) * 1988-11-17 1989-09-10 Hybritech Inc Bifunctional chimeric antibodies
IL89490A0 (en) * 1988-11-17 1989-09-10 Hybritech Inc Chimeric antibodies directed against metal chelates

Also Published As

Publication number Publication date
AU3107489A (en) 1990-05-24
DK108189D0 (da) 1989-03-07
AU618324B2 (en) 1991-12-19
IL89491A0 (en) 1989-09-10
EP0369566A3 (en) 1991-10-16
JPH02145187A (ja) 1990-06-04
EP0369566A2 (en) 1990-05-23

Similar Documents

Publication Publication Date Title
DK108589A (da) Chimere antistoffer rettet mod humant carcinoembryonalt antigen samt dna-sekvenser, der koder for saadanne antistoffer
DK108189A (da) Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer
DE68911113D1 (de) Kodiereinrichtung.
NO892449D0 (no) Gruspakkeapparat.
DK217889A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase
DE68924227D1 (de) DNA-Fragment.
DK296189D0 (da) Nucleinsyresekvenser, som koder for peptidsekvenser af carcinoembryonisk antigen-familien
MX9203598A (es) Polipeptido novedoso y secuencias de adn que codifican para la sintesis de eritropoyetina.
NO891818D0 (no) T4-reseptor-protein, relaterte dna-sekvenser samt fremstilling derav.
FI894749A0 (fi) Monteringsenhet foer hiss.
DE68922772D1 (de) Verfahren zur Zeichenkettenermittlung.
DK38989A (da) Dna-sekvens
NO881384D0 (no) Peptider.
DE68922166D1 (de) Chiffrierverfahren mit nachträglicher Quellenkodierung.
NO885108D0 (no) Peptider.
DE68914933D1 (de) Abrasionsprüfgeräte.
DK606088A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase
DK461287D0 (da) Disazoforbindelser og praeparater, der indeholder disse forbindelser.
DK1484A (da) Dna, der coder for en signalaminosyresekvens, og dna, som indeholder samme
NO905561D0 (no) Proteiner og nukleinsyrer.
DE68908528D1 (de) Testmethode.
FI893450A (fi) Modifierade proteiner.
DK151788D0 (da) Hybridserpiner og dna, som koder derfor
DK324287D0 (da) Antistof mod koensspecifikt antigen
DK578189A (da) Dna-sekvens

Legal Events

Date Code Title Description
ATS Application withdrawn