DK107811C - Fremgangsmåde til fremstilling af 3-substituerede 2H-1,4-benzodiazepin-2-oner. - Google Patents

Fremgangsmåde til fremstilling af 3-substituerede 2H-1,4-benzodiazepin-2-oner.

Info

Publication number
DK107811C
DK107811C DK278464AA DK278464A DK107811C DK 107811 C DK107811 C DK 107811C DK 278464A A DK278464A A DK 278464AA DK 278464 A DK278464 A DK 278464A DK 107811 C DK107811 C DK 107811C
Authority
DK
Denmark
Prior art keywords
benzodiazepin
ones
substituted
preparation
Prior art date
Application number
DK278464AA
Other languages
Danish (da)
English (en)
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of DK107811C publication Critical patent/DK107811C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK278464AA 1963-06-04 1963-06-19 Fremgangsmåde til fremstilling af 3-substituerede 2H-1,4-benzodiazepin-2-oner. DK107811C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US285500A US3296249A (en) 1963-06-04 1963-06-04 5-monocyclic aryl-1, 3-dihydro-2h-1, 4-benzodiazepin-2-ones

Publications (1)

Publication Number Publication Date
DK107811C true DK107811C (da) 1967-07-10

Family

ID=23094505

Family Applications (1)

Application Number Title Priority Date Filing Date
DK278464AA DK107811C (da) 1963-06-04 1963-06-19 Fremgangsmåde til fremstilling af 3-substituerede 2H-1,4-benzodiazepin-2-oner.

Country Status (7)

Country Link
US (1) US3296249A (ko)
DE (1) DE1445424A1 (ko)
DK (1) DK107811C (ko)
ES (1) ES291045A2 (ko)
FI (1) FI46847C (ko)
NL (1) NL298071A (ko)
SE (1) SE310884B (ko)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3401159A (en) * 1966-02-14 1968-09-10 American Home Prod Benzodiazepine derivatives
US3549623A (en) * 1968-11-14 1970-12-22 Warner Lambert Pharmaceutical 7-r1-1-(r2)-3-hydroxy-5-phenyl-1h-1,4-benzodiazepin-2(3h)-one
US3867529A (en) * 1970-08-24 1975-02-18 Giorgio Ferrari Tranquilizing and anti-anxiety pharmaceutical compositions
US4065451A (en) * 1971-03-30 1977-12-27 American Home Products 1,3-Dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one, substituted diamino acetate esters and their acid salts
US3886276A (en) * 1971-03-30 1975-05-27 American Home Prod 1,3-Dihydro-3 -hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one, substituted diamino acetate esters and their acid salts in compositions and methods for inducing a calming effect
BE788899A (fr) * 1971-09-15 1973-01-02 Crc Ricerca Chim Procede de preparation de derives de benzodiazepine-1,4 one-2 utiles notamment comme agents tranquillisants et sedatifs
US4008223A (en) * 1971-12-09 1977-02-15 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
USRE31071E (en) * 1971-12-09 1982-11-02 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
US4017616A (en) * 1972-01-21 1977-04-12 American Home Products Corporation Parenteral benzodiazepine compositions
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
US3926952A (en) * 1972-10-03 1975-12-16 American Home Prod 1,4-Benzodiazepin-2-ones and their synthesis
US3860581A (en) * 1972-12-27 1975-01-14 American Home Prod Preparation of 1,4-benzodiazepines
US4232016A (en) * 1974-12-20 1980-11-04 Merck Patent Gesellschaft Mit Beschraenkter Haftung 3-Fluorobenzodiazepines
US4246270A (en) * 1976-05-26 1981-01-20 E. I. Du Pont De Nemours And Company 3-Fluorobenzodiazepines and compositions and uses thereof
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
GR76455B (ko) * 1981-06-04 1984-08-10 Lepetit Spa
US4412952A (en) * 1982-04-30 1983-11-01 Sandoz, Inc. Process for 3-hydroxy benzodiazepinones
US5382596A (en) * 1993-08-05 1995-01-17 Whitby Research, Inc. Substituted 2-aminotetralins
WO2001066062A2 (en) * 2000-03-06 2001-09-13 Teva Pharmaqceutical Industries Ltd. Process for preparing pure crystalline lorazepam
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7458374B2 (en) * 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20070122353A1 (en) * 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7090830B2 (en) * 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US20040105818A1 (en) * 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) * 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US20040234699A1 (en) 2003-05-21 2004-11-25 Alexza Molecular Delivery Corporation Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
PT1691811E (pt) 2003-12-11 2014-10-30 Sunovion Pharmaceuticals Inc Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
US7540286B2 (en) * 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
US20100006092A1 (en) * 2004-08-12 2010-01-14 Alexza Pharmaceuticals, Inc. Aerosol Drug Delivery Device Incorporating Percussively Activated Heat Packages
AU2004322756B2 (en) * 2004-08-12 2011-04-14 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) * 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
EP1991212A1 (en) * 2006-03-08 2008-11-19 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US20100009983A1 (en) * 2006-05-09 2010-01-14 Braincells, Inc. 5 ht receptor mediated neurogenesis
MX2008014320A (es) * 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2068872A1 (en) * 2006-09-08 2009-06-17 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
EP2066355A2 (en) * 2006-09-19 2009-06-10 Braincells, Inc. Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
US20090258865A1 (en) * 2008-03-28 2009-10-15 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
US10289671B2 (en) * 2008-05-07 2019-05-14 Microsoft Technology Licensing, Llc Graphically displaying selected data sources within a grid
WO2010046929A2 (en) * 2008-10-17 2010-04-29 Matrix Laboratories Limited Novel polymorphic forms of temazepam and processes for preparing the same
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
PL3415139T3 (pl) 2011-06-14 2022-07-11 Neurelis, Inc. Podawanie benzodiazepiny
SG11201505352RA (en) 2013-01-09 2015-08-28 Edgemont Pharmaceuticals Llc Controlled release formulations of lorazepam
US8999393B1 (en) 2013-01-09 2015-04-07 Edgemont Pharmaceuticals Llc Sustained release formulations of lorazepam
CN105601576A (zh) * 2016-03-18 2016-05-25 山东新华制药股份有限公司 氯甲西泮的晶型及其制备方法
CN110776473B (zh) * 2019-11-19 2023-09-15 湖南洞庭药业股份有限公司 制备劳拉西泮的方法

Also Published As

Publication number Publication date
ES291045A2 (es) 1963-12-16
DE1445424A1 (de) 1969-02-20
FI46847B (ko) 1973-04-02
US3296249A (en) 1967-01-03
NL298071A (ko)
SE310884B (ko) 1969-05-19
FI46847C (fi) 1973-07-10

Similar Documents

Publication Publication Date Title
DK107811C (da) Fremgangsmåde til fremstilling af 3-substituerede 2H-1,4-benzodiazepin-2-oner.
DK106552C (da) Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner.
DK127415B (da) Fremgangsmåde til fremstilling af α-benzyl-β,β-dialkoxypropionitriler.
DK117957B (da) Fremgangsmåde til fremstilling af 13β-alkyl-3-oxogona-4,9,11-triener.
DK125856B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepiner.
DK120492B (da) Fremgangsmåde til fremstilling af 3-acylamido-5-aryl-1,3-dihydro-2H-1,4-benzodiazepin-2-on-forbindelser.
DK106185C (da) Fremgangsmåde til fremstilling af 17α-acyloxy-4,6-pregnadien-20-oner.
DK116511B (da) Fremgangsmåde til fremstilling af substituerede 1,4-benzodiazepinforbindelser.
DK119107B (da) Fremgangsmåde til fremstilling af 11β-hydroperoxy-3-oxo-13-alkyl-Δ<4,9>-gonadiener.
DK106328C (da) Fremgangsmåde til fremstilling af 17α-alkoxy-16-methylen-3,20-diketopregnanderivater.
DK124823B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK121759B (da) Analogifremgangsmåde til fremstilling af 3-oxo-7α-methylgona-4,9-diener.
DK117499B (da) Fremgangsmåde til fremstilling af 1,3-dihydro-3-hydroxy-1,4-benzodiazepin-2-oner.
DK106329C (da) Fremgangsmåde til fremstilling af 3,20-dioxo-19-nor-4,9,11-pregnatrien.
DK128279B (da) Fremgangsmåde til fremstilling af α,ω-alkylendiaminer.
DK138370B (da) Fremgangsmåde til fremstilling af 1-methyl-7-halogen-2,3-dihyro-5-phenyl-1,4-benzodiazepiner.
DK109895C (da) Fremgangsmåde til fremstilling af 1,3-dioxo-2-alkyl-cyclopentaner.
DK114904B (da) Fremgangsmåde til fremstilling af 3,5-diiodthyroniner.
DK126115B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK122079B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepinderivater.
DK117956B (da) Fremgangsmåde til fremstilling af 3-oxogona-4,9-diener.
DK114204B (da) Fremgangsmåde til fremstilling af carboxamidoalkyl-1,3-benzoxaziner.
DK109137C (da) Fremgangsmåde til fremstilling af propionaldehyd.
DK127253B (da) Fremgangsmåde til fremstilling af 1,4-benzodiazepiner.
DK131723B (da) Analogifremgangsmåde til fremstilling af 3-substituerede 2H-1,4-benzodiazepin-2-oner.