DK1063294T3 - DNA'er eller gener der deltager i Parkinsons sygdom - Google Patents

DNA'er eller gener der deltager i Parkinsons sygdom

Info

Publication number
DK1063294T3
DK1063294T3 DK99902859T DK99902859T DK1063294T3 DK 1063294 T3 DK1063294 T3 DK 1063294T3 DK 99902859 T DK99902859 T DK 99902859T DK 99902859 T DK99902859 T DK 99902859T DK 1063294 T3 DK1063294 T3 DK 1063294T3
Authority
DK
Denmark
Prior art keywords
disease
parkinson
dnas
genes involved
sequence
Prior art date
Application number
DK99902859T
Other languages
Danish (da)
English (en)
Inventor
Yoshikuni Mizuno
Nobuyoshi Shimizu
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK1063294T3 publication Critical patent/DK1063294T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99902859T 1998-02-09 1999-02-09 DNA'er eller gener der deltager i Parkinsons sygdom DK1063294T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2753198 1998-02-09

Publications (1)

Publication Number Publication Date
DK1063294T3 true DK1063294T3 (da) 2006-05-22

Family

ID=12223704

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99902859T DK1063294T3 (da) 1998-02-09 1999-02-09 DNA'er eller gener der deltager i Parkinsons sygdom

Country Status (10)

Country Link
US (2) US6716621B1 (fr)
EP (1) EP1063294B1 (fr)
JP (1) JP4430815B2 (fr)
AT (1) ATE315645T1 (fr)
AU (1) AU2299999A (fr)
CA (1) CA2320220C (fr)
DE (2) DE1063294T1 (fr)
DK (1) DK1063294T3 (fr)
ES (1) ES2257029T3 (fr)
WO (1) WO1999040191A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2775984B1 (fr) * 1998-03-11 2006-09-15 Bioscreen Therapeutics Sa Criblage differentiel qualitatif
ATE315645T1 (de) * 1998-02-09 2006-02-15 Boehringer Ingelheim Int Dns oder gene, die an der parkinsonschen krankheit beteiligt sind
DK1131424T3 (da) * 1998-11-19 2009-11-23 Aventis Pharma Sa Mutationer af Pakin-genet, sammensætninger, fremgangsmåder samt anvendelser
CA2996759A1 (fr) 1998-11-19 2000-06-02 Aventis Pharma S.A. Mutations du gene de la parkine, compositions, methodes et utilisations
EP1081225A1 (fr) * 1999-08-30 2001-03-07 Biofrontera Pharmaceuticals GmbH Modèle animal transgénique de maladies neurodégénératives
EP1262557B1 (fr) * 2000-02-24 2006-10-18 Boehringer Ingelheim International GmbH Proteine parkine utilisee comme ubiquitine ligase
AU2001260140A1 (en) 2000-03-22 2001-10-03 Avntis Pharma Deutschland Gmbh Nematodes as model organisms for the investigation of neurodegenerative diseases, in particular parkinsons disease, uses and methods for the discovery of substances and genes which can be used in the treatment of the above disease states and identification of a nematode gene.
US7070940B2 (en) * 2002-07-18 2006-07-04 Aventis Pharma S.A. Method for determining the ability of a compound to modify the interaction between parkin and the p38 protein
US8506959B2 (en) 2002-11-01 2013-08-13 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
US8697082B2 (en) 2002-11-01 2014-04-15 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
US20080014194A1 (en) 2003-10-31 2008-01-17 Elan Pharmaceuticals, Inc. Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
US9034337B2 (en) 2003-10-31 2015-05-19 Prothena Biosciences Limited Treatment and delay of outset of synucleinopathic and amyloidogenic disease
TW200509968A (en) 2002-11-01 2005-03-16 Elan Pharm Inc Prevention and treatment of synucleinopathic disease
US7358331B2 (en) 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
US7674599B2 (en) 2003-11-08 2010-03-09 Elan Pharmaceuticals, Inc. Methods of using antibodies to detect alpha-synuclein in fluid samples
JP5329434B2 (ja) 2007-01-31 2013-10-30 エラン・フアルマ・インターナシヨナル・リミテツド 新規基質を使用したパーキン活性のモジュレーターのアッセイ方法
US8147833B2 (en) 2007-02-23 2012-04-03 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
EP2118300B1 (fr) 2007-02-23 2015-05-27 Prothena Biosciences Limited Prévention et traitement de maladies synucléinopathiques et amyloïdogéniques

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE315645T1 (de) * 1998-02-09 2006-02-15 Boehringer Ingelheim Int Dns oder gene, die an der parkinsonschen krankheit beteiligt sind

Also Published As

Publication number Publication date
ES2257029T3 (es) 2006-07-16
EP1063294A1 (fr) 2000-12-27
ATE315645T1 (de) 2006-02-15
DE69929417T2 (de) 2006-08-03
DE69929417D1 (de) 2006-04-06
EP1063294A4 (fr) 2002-01-16
EP1063294B1 (fr) 2006-01-11
AU2299999A (en) 1999-08-23
JP4430815B2 (ja) 2010-03-10
WO1999040191A1 (fr) 1999-08-12
DE1063294T1 (de) 2003-06-26
US6716621B1 (en) 2004-04-06
CA2320220A1 (fr) 1999-08-12
US20050003385A1 (en) 2005-01-06
CA2320220C (fr) 2011-08-02

Similar Documents

Publication Publication Date Title
DK1063294T3 (da) DNA'er eller gener der deltager i Parkinsons sygdom
ES2066760T3 (es) Nucleotidos de alquinilamino.
DK1013661T3 (da) 2'-O,4'-metylen bicyklonukleosid
ATE232880T1 (de) Neue nucleotidanaloga
DE69834056D1 (de) De novo oder "universaler" sequenzierungs-array
DE69729122D1 (de) KüNSTLICHE FEHLHYBRIDISIERUNG
IL144374A0 (en) Method of identifying cytosine methylation patterns in genomic dna samples
PT920498E (pt) Adn regulador transcricional de ef-1x de hamster
DE69736840D1 (de) Synthese von nukleosiden und polynukleotiden
DK0960192T3 (da) Syntetiske polynukleotider
CA2195971A1 (fr) Sondes de detection par hybridation d'acides nucleiques ciblant les acides nucleiques de mycoplasma pneumoniae
CY1108240T1 (el) ΑΠΟΜΟΝΩΜΕΝΑ ΠΟΛΥΝΟΥΚΛΕΟΤΙΔΙΑ ΤΑ ΟΠΟΙΑ ΕΧΟΥΝ ΕΝΑ ΜΕΙΩΜΕΝΟ ΠΕΡΙΕΧΟΜΕΝΟ ΜΟΤΙΒΩΝ 5΄CpG3΄ ΕΠΙΓΕΝΕΤΙΚΟΥ ΕΛΕΓΧΟΥ ΚΑΙ ΟΙ ΧΡΗΣΕΙΣ ΤΟΥΣ
ATE386819T1 (de) Verfahren zur analyse von aflp reaktionsmischungen unter verwendung von primer verlängerungstechniken
WO2000063441A3 (fr) Polymorphismes de nucleotides simples dans des genes mitochondriaux qui segregent avec la maladie d'alzheimer
ATE242261T1 (de) Fluoreszend-konjugaten von nukleosiden und von nukleotiden, ihrer verfahren zur herstellung und ihrer verwendungen
DK1108786T3 (da) Hidtil ukendt kollektin
ATE270331T1 (de) Rezeptor und dafür kodierendes nukleinsäuremolekül
NO995858L (no) Ny klasse kationiske nukleinsyre-overføringsmidler
TR199902434T2 (xx) Bakteriyel plazmidler.
ATE350489T1 (de) Diagnose von mit humos assoziierten krankheiten
DE59914061D1 (de) Das gen prv-1 und dessen verwendung
DE20111754U1 (de) Leitfähigkeits-Hybridisierung
DK1317548T3 (da) Transglutaminasegenprodukter
CY1113694T1 (el) Πιστοποιηση μιας παραλλαγης dna που συνδυαζεται με υπολακτασια τυπου-ενηλικα
WO2003014342A3 (fr) Identification d'une variante d'adn associee a l'hypolactasie de type adulte