DE1063294T1 - Dns oder gene, die an der parkinsonschen krankheit beteiligt sind - Google Patents

Dns oder gene, die an der parkinsonschen krankheit beteiligt sind

Info

Publication number
DE1063294T1
DE1063294T1 DE1063294T DE99902859T DE1063294T1 DE 1063294 T1 DE1063294 T1 DE 1063294T1 DE 1063294 T DE1063294 T DE 1063294T DE 99902859 T DE99902859 T DE 99902859T DE 1063294 T1 DE1063294 T1 DE 1063294T1
Authority
DE
Germany
Prior art keywords
disease
parkinson
dna
genes involved
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE1063294T
Other languages
English (en)
Inventor
Nobuyoshi Shimizu
Yoskikuni Mizuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of DE1063294T1 publication Critical patent/DE1063294T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE1063294T 1998-02-09 1999-02-09 Dns oder gene, die an der parkinsonschen krankheit beteiligt sind Pending DE1063294T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2753198 1998-02-09
PCT/JP1999/000545 WO1999040191A1 (fr) 1998-02-09 1999-02-09 Adn ou genes contribuant au developpement de la maladie de parkinson

Publications (1)

Publication Number Publication Date
DE1063294T1 true DE1063294T1 (de) 2003-06-26

Family

ID=12223704

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1063294T Pending DE1063294T1 (de) 1998-02-09 1999-02-09 Dns oder gene, die an der parkinsonschen krankheit beteiligt sind
DE69929417T Expired - Lifetime DE69929417T2 (de) 1998-02-09 1999-02-09 Dns oder gene, die an der parkinsonschen krankheit beteiligt sind

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69929417T Expired - Lifetime DE69929417T2 (de) 1998-02-09 1999-02-09 Dns oder gene, die an der parkinsonschen krankheit beteiligt sind

Country Status (10)

Country Link
US (2) US6716621B1 (de)
EP (1) EP1063294B1 (de)
JP (1) JP4430815B2 (de)
AT (1) ATE315645T1 (de)
AU (1) AU2299999A (de)
CA (1) CA2320220C (de)
DE (2) DE1063294T1 (de)
DK (1) DK1063294T3 (de)
ES (1) ES2257029T3 (de)
WO (1) WO1999040191A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2775984B1 (fr) * 1998-03-11 2006-09-15 Bioscreen Therapeutics Sa Criblage differentiel qualitatif
ES2257029T3 (es) * 1998-02-09 2006-07-16 Boehringer Ingelheim International Gmbh Dnas o genes que participan en la enfermedad de parkinson.
US7998667B1 (en) 1998-11-19 2011-08-16 Aventis Pharma S.A. Mutations of the parkin gene, compositions, methods and uses
ATE440138T1 (de) * 1998-11-19 2009-09-15 Aventis Pharma Sa Mutationen des parkin-gens, zusammensetzungen, verfahren und verwendungen
EP1081225A1 (de) * 1999-08-30 2001-03-07 Biofrontera Pharmaceuticals GmbH Transgenes Tiermodel für neurodegenerative Erkrankungen
CA2398703A1 (en) * 2000-02-24 2001-08-30 Boehringer Ingelheim International Gmbh Parkin protein as ubiquitin ligase
AU2001260140A1 (en) 2000-03-22 2001-10-03 Avntis Pharma Deutschland Gmbh Nematodes as model organisms for the investigation of neurodegenerative diseases, in particular parkinsons disease, uses and methods for the discovery of substances and genes which can be used in the treatment of the above disease states and identification of a nematode gene.
US7070940B2 (en) * 2002-07-18 2006-07-04 Aventis Pharma S.A. Method for determining the ability of a compound to modify the interaction between parkin and the p38 protein
TW200509968A (en) * 2002-11-01 2005-03-16 Elan Pharm Inc Prevention and treatment of synucleinopathic disease
US8697082B2 (en) 2002-11-01 2014-04-15 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
US9034337B2 (en) 2003-10-31 2015-05-19 Prothena Biosciences Limited Treatment and delay of outset of synucleinopathic and amyloidogenic disease
US20080014194A1 (en) 2003-10-31 2008-01-17 Elan Pharmaceuticals, Inc. Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease
US8506959B2 (en) 2002-11-01 2013-08-13 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
US7358331B2 (en) 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
US7674599B2 (en) 2003-11-08 2010-03-09 Elan Pharmaceuticals, Inc. Methods of using antibodies to detect alpha-synuclein in fluid samples
US7790365B2 (en) 2007-01-31 2010-09-07 Elan Pharma International Limited Assays for modulators of parkin activity using S5a as a parkin substrate
US8147833B2 (en) 2007-02-23 2012-04-03 Neotope Biosciences Limited Prevention and treatment of synucleinopathic and amyloidogenic disease
PL2118300T3 (pl) 2007-02-23 2015-11-30 Prothena Biosciences Ltd Zapobieganie i leczenie synukleinopatii i amyloidozy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2257029T3 (es) * 1998-02-09 2006-07-16 Boehringer Ingelheim International Gmbh Dnas o genes que participan en la enfermedad de parkinson.

Also Published As

Publication number Publication date
ATE315645T1 (de) 2006-02-15
CA2320220A1 (en) 1999-08-12
JP4430815B2 (ja) 2010-03-10
EP1063294A1 (de) 2000-12-27
EP1063294A4 (de) 2002-01-16
US20050003385A1 (en) 2005-01-06
DK1063294T3 (da) 2006-05-22
ES2257029T3 (es) 2006-07-16
DE69929417D1 (de) 2006-04-06
AU2299999A (en) 1999-08-23
WO1999040191A1 (fr) 1999-08-12
DE69929417T2 (de) 2006-08-03
EP1063294B1 (de) 2006-01-11
US6716621B1 (en) 2004-04-06
CA2320220C (en) 2011-08-02

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