DK1056475T3 - Dendrimere fullerenderivater, fremgangsmåde til fremstilling heraf samt deres anvendelse som neuroprotektiva - Google Patents

Dendrimere fullerenderivater, fremgangsmåde til fremstilling heraf samt deres anvendelse som neuroprotektiva

Info

Publication number
DK1056475T3
DK1056475T3 DK99904807T DK99904807T DK1056475T3 DK 1056475 T3 DK1056475 T3 DK 1056475T3 DK 99904807 T DK99904807 T DK 99904807T DK 99904807 T DK99904807 T DK 99904807T DK 1056475 T3 DK1056475 T3 DK 1056475T3
Authority
DK
Denmark
Prior art keywords
dendrimers
preparation
fullerene derivatives
neuroprotective agents
fullerene
Prior art date
Application number
DK99904807T
Other languages
English (en)
Inventor
Andreas Hirsch
Original Assignee
Siemens Axiva Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Axiva Gmbh & Co Kg filed Critical Siemens Axiva Gmbh & Co Kg
Application granted granted Critical
Publication of DK1056475T3 publication Critical patent/DK1056475T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2604/00Fullerenes, e.g. C60 buckminsterfullerene or C70
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/734Fullerenes, i.e. graphene-based structures, such as nanohorns, nanococoons, nanoscrolls or fullerene-like structures, e.g. WS2 or MoS2 chalcogenide nanotubes, planar C3N4, etc.
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/778Nanostructure within specified host or matrix material, e.g. nanocomposite films
    • Y10S977/786Fluidic host/matrix containing nanomaterials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Polyamides (AREA)
DK99904807T 1998-02-25 1999-01-23 Dendrimere fullerenderivater, fremgangsmåde til fremstilling heraf samt deres anvendelse som neuroprotektiva DK1056475T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19807979A DE19807979C2 (de) 1998-02-25 1998-02-25 Dendrimere Fullerenderivate, Verfahren zur Herstellung und Verwendung als Neuroprotektiva
PCT/EP1999/000439 WO1999043358A1 (de) 1998-02-25 1999-01-23 Dendrimere fullerenderivate, verfahren zur herstellung und verwendung als neuroprotektiva

Publications (1)

Publication Number Publication Date
DK1056475T3 true DK1056475T3 (da) 2003-08-11

Family

ID=7858910

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99904807T DK1056475T3 (da) 1998-02-25 1999-01-23 Dendrimere fullerenderivater, fremgangsmåde til fremstilling heraf samt deres anvendelse som neuroprotektiva

Country Status (8)

Country Link
US (1) US6506928B1 (da)
EP (1) EP1056475B1 (da)
JP (1) JP4671503B2 (da)
AT (1) ATE238814T1 (da)
DE (2) DE19807979C2 (da)
DK (1) DK1056475T3 (da)
ES (1) ES2200499T3 (da)
WO (1) WO1999043358A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200307563A (en) * 2002-02-14 2003-12-16 Sixty Inc C Use of BUCKYSOME or carbon nanotube for drug delivery
US20050058675A1 (en) * 2003-04-10 2005-03-17 Wilson Stephen R. Fullerene compositions for ameliorating dermatological conditions
AU2004229497A1 (en) * 2003-04-10 2004-10-28 Luna Innovations Incorporated Fullerene compositions for ameliorating dermatological conditions
JP4322540B2 (ja) * 2003-04-15 2009-09-02 匡彦 増野 フラーレンウイスカー及びフラーレンウイスカーの製造方法
US7163956B2 (en) * 2003-10-10 2007-01-16 C Sixty Inc. Substituted fullerene compositions and their use as antioxidants
US20050288236A1 (en) * 2003-10-10 2005-12-29 Russ Lebovitz Substituted fullerene formulations and their use in ameliorating oxidative stress diseases or inhibiting cell death
US20060247152A1 (en) * 2005-05-02 2006-11-02 Russ Lebovitz Substituted fullerenes and their use as inhibitors of cell death
US7507764B2 (en) * 2003-10-15 2009-03-24 Tego Biosciences Corporation Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes
TW200535092A (en) 2003-12-15 2005-11-01 Nano C Inc High efficiency fullerene-based radical scavengers
JP4636239B2 (ja) * 2003-12-26 2011-02-23 株式会社ファインラバー研究所 Led用蛍光組成物、led用蛍光部材及び半導体発光装置
US20080004345A1 (en) * 2004-03-31 2008-01-03 Yasuhiko Tabata Novel Water-Soluble Fullerene, Process for Producing the Same and Active Oxygen Generator Containing the Fullerene
WO2006028635A2 (en) * 2004-09-02 2006-03-16 C Sixty Inc. Fullerene compositions for ameliorating hearing loss, collateral damage of chemotherapy, or mucositis
JP2006160664A (ja) * 2004-12-07 2006-06-22 Vitamin C60 Bioresearch Kk フリーラジカル疾患予防治療用組成物
WO2006078257A1 (en) * 2005-01-19 2006-07-27 C Sixty Inc. Substituted fullerene compositions and their use in treatment of shock
US20080020977A1 (en) * 2005-11-21 2008-01-24 Russ Lebovitz Use of Fullerenes to Oxidize Reduced Redox Proteins
TW201025703A (en) * 2008-12-31 2010-07-01 Taiwan Textile Res Inst Organic thin-film solar cell using fullerene derivative as electron acceptor and method of fabricating the same
BR112012009847B1 (pt) * 2009-10-26 2021-04-13 Dendritc Nanotechnologies, Inc. Formulação compreendendo dendrímeros peham para uso em agricultura, e método para tratamento de plantas ou sementes
WO2011085185A1 (en) 2010-01-08 2011-07-14 Liang-Shi Li Soluble graphene nanostructures and assemblies therefrom
EP2565248B1 (en) * 2010-04-28 2017-11-08 Korea Research Institute of Bioscience and Biotechnology Water-soluble fluorescent fullerene derivative, and preparation method thereof
CN112957373B (zh) * 2021-03-23 2022-04-08 山东大学 一种丙氨酸修饰的富勒烯纳米材料、其制备方法及在神经修复领域的应用
CN113625088A (zh) * 2021-08-17 2021-11-09 国网四川省电力公司电力科学研究院 基于学习脉冲神经膜系统的变压器故障诊断方法

Also Published As

Publication number Publication date
EP1056475A1 (de) 2000-12-06
WO1999043358A1 (de) 1999-09-02
JP4671503B2 (ja) 2011-04-20
EP1056475B1 (de) 2003-05-02
JP2002504525A (ja) 2002-02-12
DE19807979C2 (de) 2003-02-06
DE59905324D1 (de) 2003-06-05
ES2200499T3 (es) 2004-03-01
US6506928B1 (en) 2003-01-14
DE19807979A1 (de) 1999-08-26
ATE238814T1 (de) 2003-05-15

Similar Documents

Publication Publication Date Title
DK1056475T3 (da) Dendrimere fullerenderivater, fremgangsmåde til fremstilling heraf samt deres anvendelse som neuroprotektiva
ECSP034450A (es) Nueva composicion farmaceutica
NO20071095L (no) Hittil ukjente tiofenderivater
ATE433973T1 (de) Azolylaminoazine als inhibitoren von proteinkinasen
FR2841900B1 (fr) Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations
FI20001017A (fi) Näppäimistön valaisujärjestely, joka mahdollistaa näppäinten muuttuvan ja yksilöllisen valaisemisen, sekä menetelmä sen käyttämiseksi
ATE306916T1 (de) Neue fettanaloge zur behandlung von sekundärer restenose
NO20025860D0 (no) Fremgangsmåte for opprettholding av formasjonsstabilitet i sanntid
LU92146I2 (fr) Dasatinib et ses sels pharmaceutiquement acceptables
AU2019502A (en) Anilinopyrimidine derivatives as ikk inhibitors and compositions and methods related thereto
BRPI0518228B8 (pt) inibidores de cinesina mitótica e uso dos mesmos
BR0013180A (pt) Oligonucleotìdeos para inibição da expressão de eg5 humano
BR0107749A (pt) Métodos de uso de uma composição de bebida
DE60013098D1 (de) Zusammensetzung zur hautdesinfizierung
DK1123414T3 (da) Antisense-modulering af integrin alpha 4.ekspression
NO20002798D0 (no) Sammensetninger og metoder for Õ øke konsentrasjonen og/eller bevegeligheten av spermatozoa hos mennesker
IS5651A (is) Efni til að bæta verkfræðilega eiginleika jarðvegs
PT1107793E (pt) Conjugados de dextrano-leptina, composicoes farmaceuticas e processos relacionados
TR200402070T4 (tr) Siklobüten-dion türevleri ve bunların damar sertliği tedavisinde kullanımı
IL144199A0 (en) Novel bretylium compositions and kits, and their use in preventing and treating cardiovascular conditions
BR0111785A (pt) Composições e métodos para tratamento de candidìase
ATE400285T1 (de) Mischungen von isoflavonen und flavonen
MXPA02011940A (es) Estuches y metodos para optimizar la eficacia de composiciones condroprotectoras.
AR026606A1 (es) Un metodo para prevenir la diarrea
PT1276722E (pt) Inibidores de naftamidina-uroquinase