DK1044364T3 - Fremgangmåde og reagenser til kvantificering af fastfasereaktioner ved anvendelse af fluor-NMR - Google Patents
Fremgangmåde og reagenser til kvantificering af fastfasereaktioner ved anvendelse af fluor-NMRInfo
- Publication number
- DK1044364T3 DK1044364T3 DK98966876T DK98966876T DK1044364T3 DK 1044364 T3 DK1044364 T3 DK 1044364T3 DK 98966876 T DK98966876 T DK 98966876T DK 98966876 T DK98966876 T DK 98966876T DK 1044364 T3 DK1044364 T3 DK 1044364T3
- Authority
- DK
- Denmark
- Prior art keywords
- reagents
- methods
- solid phase
- phase reactions
- fluorine nmr
- Prior art date
Links
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 229910052731 fluorine Inorganic materials 0.000 title abstract 2
- 239000011737 fluorine Substances 0.000 title abstract 2
- 238000003746 solid phase reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000007790 solid phase Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/12—Hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/14—Esterification
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/18—Introducing halogen atoms or halogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/18—Introducing halogen atoms or halogen-containing groups
- C08F8/20—Halogenation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/26—Removing halogen atoms or halogen-containing groups from the molecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/34—Introducing sulfur atoms or sulfur-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
- C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2810/00—Chemical modification of a polymer
- C08F2810/20—Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
- G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- High Energy & Nuclear Physics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Steroid Compounds (AREA)
- Catalysts (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1997/023920 WO1998029376A1 (en) | 1996-12-19 | 1997-12-17 | Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds |
| US9056398P | 1998-06-24 | 1998-06-24 | |
| US9055898P | 1998-06-24 | 1998-06-24 | |
| PCT/US1998/026512 WO1999031491A1 (en) | 1997-12-17 | 1998-12-14 | Method and reagents for the quantification of solid-phase reactions using fluorine nmr |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1044364T3 true DK1044364T3 (da) | 2007-09-24 |
Family
ID=27376603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98966876T DK1044364T3 (da) | 1997-12-17 | 1998-12-14 | Fremgangmåde og reagenser til kvantificering af fastfasereaktioner ved anvendelse af fluor-NMR |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1044364B8 (enExample) |
| JP (1) | JP2003522934A (enExample) |
| CN (1) | CN1205468C (enExample) |
| AT (1) | ATE364837T1 (enExample) |
| AU (1) | AU748529C (enExample) |
| BG (1) | BG65184B1 (enExample) |
| BR (1) | BR9813701A (enExample) |
| CA (1) | CA2315152A1 (enExample) |
| DE (1) | DE69837936T2 (enExample) |
| DK (1) | DK1044364T3 (enExample) |
| ES (1) | ES2288310T3 (enExample) |
| HU (1) | HUP0200726A2 (enExample) |
| IL (1) | IL136718A0 (enExample) |
| MX (1) | MXPA00006050A (enExample) |
| PL (1) | PL197620B1 (enExample) |
| WO (1) | WO1999031491A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2280272A1 (en) * | 2000-09-27 | 2011-02-02 | Universiteit Leiden | Method for applying NMR for ligand discovery or as a drug screening tool |
| FR2955862B1 (fr) * | 2010-02-02 | 2012-07-13 | Commissariat Energie Atomique | Materiau polymere fluorocarbone et procede de synthese |
| CN103487455B (zh) * | 2013-09-24 | 2016-04-27 | 上海大学 | 一种快速定量检测橄榄油中含羟基化合物的方法 |
| CN108593696B (zh) * | 2018-04-26 | 2020-11-03 | 南京明捷生物医药检测有限公司 | 一种利用定量核磁测定多肽中三氟乙酸残留的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5565324A (en) * | 1992-10-01 | 1996-10-15 | The Trustees Of Columbia University In The City Of New York | Complex combinatorial chemical libraries encoded with tags |
| US5566324A (en) * | 1992-12-24 | 1996-10-15 | Ncr Corporation | Computer apparatus including a main memory prefetch cache and method of operation thereof |
| GB9515070D0 (en) * | 1995-07-22 | 1995-09-20 | Zeneca Ltd | Label |
| US6355490B1 (en) * | 1996-09-13 | 2002-03-12 | Jill Edie Hochlowski | Attached tags for use in combinatorial chemistry synthesis |
-
1998
- 1998-12-14 AU AU25569/99A patent/AU748529C/en not_active Ceased
- 1998-12-14 CA CA002315152A patent/CA2315152A1/en not_active Abandoned
- 1998-12-14 HU HU0200726A patent/HUP0200726A2/hu unknown
- 1998-12-14 DK DK98966876T patent/DK1044364T3/da active
- 1998-12-14 BR BR9813701-8A patent/BR9813701A/pt not_active Application Discontinuation
- 1998-12-14 PL PL341357A patent/PL197620B1/pl not_active IP Right Cessation
- 1998-12-14 MX MXPA00006050A patent/MXPA00006050A/es active IP Right Grant
- 1998-12-14 WO PCT/US1998/026512 patent/WO1999031491A1/en not_active Ceased
- 1998-12-14 AT AT98966876T patent/ATE364837T1/de not_active IP Right Cessation
- 1998-12-14 CN CNB988133334A patent/CN1205468C/zh not_active Expired - Fee Related
- 1998-12-14 ES ES98966876T patent/ES2288310T3/es not_active Expired - Lifetime
- 1998-12-14 IL IL13671898A patent/IL136718A0/xx active IP Right Grant
- 1998-12-14 DE DE69837936T patent/DE69837936T2/de not_active Expired - Lifetime
- 1998-12-14 EP EP98966876A patent/EP1044364B8/en not_active Expired - Lifetime
- 1998-12-14 JP JP2000539340A patent/JP2003522934A/ja active Pending
-
2000
- 2000-07-14 BG BG104614A patent/BG65184B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL197620B1 (pl) | 2008-04-30 |
| EP1044364A1 (en) | 2000-10-18 |
| PL341357A1 (en) | 2001-04-09 |
| BG104614A (en) | 2001-10-31 |
| WO1999031491A1 (en) | 1999-06-24 |
| DE69837936D1 (de) | 2007-07-26 |
| CN1205468C (zh) | 2005-06-08 |
| AU748529C (en) | 2002-10-17 |
| MXPA00006050A (es) | 2004-05-21 |
| BR9813701A (pt) | 2000-12-12 |
| EP1044364B1 (en) | 2007-06-13 |
| CN1284165A (zh) | 2001-02-14 |
| ES2288310T3 (es) | 2008-01-01 |
| DE69837936T2 (de) | 2008-02-28 |
| IL136718A0 (en) | 2001-06-14 |
| AU748529B2 (en) | 2002-06-06 |
| ATE364837T1 (de) | 2007-07-15 |
| HUP0200726A2 (en) | 2002-06-29 |
| BG65184B1 (bg) | 2007-05-31 |
| AU2556999A (en) | 1999-07-05 |
| EP1044364B8 (en) | 2008-01-02 |
| JP2003522934A (ja) | 2003-07-29 |
| EP1044364A4 (en) | 2004-10-06 |
| CA2315152A1 (en) | 1999-06-24 |
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