DK103091A - Rekombinante proteiner med adipsin- og komplement d-aktiviteter - Google Patents

Rekombinante proteiner med adipsin- og komplement d-aktiviteter Download PDF

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Publication number
DK103091A
DK103091A DK103091A DK103091A DK103091A DK 103091 A DK103091 A DK 103091A DK 103091 A DK103091 A DK 103091A DK 103091 A DK103091 A DK 103091A DK 103091 A DK103091 A DK 103091A
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DK
Denmark
Prior art keywords
adipsin
complement
activities
recombinant proteins
recombinant
Prior art date
Application number
DK103091A
Other languages
Danish (da)
English (en)
Other versions
DK103091D0 (da
Inventor
Jeffrey S Flier
Bruce M Spiegelman
Barry M Rosen
Tyler R White
Original Assignee
Beth Israel Hospital
Dana Farber Cancer Inst Inc
Metabolic Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beth Israel Hospital, Dana Farber Cancer Inst Inc, Metabolic Biosystems Inc filed Critical Beth Israel Hospital
Publication of DK103091D0 publication Critical patent/DK103091D0/da
Publication of DK103091A publication Critical patent/DK103091A/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
DK103091A 1988-11-30 1991-05-30 Rekombinante proteiner med adipsin- og komplement d-aktiviteter DK103091A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/277,963 US5223425A (en) 1987-04-02 1988-11-30 DNA encoding human adipsin with complement D activity
PCT/US1989/005374 WO1990006365A1 (fr) 1988-11-30 1989-11-21 Proteines recombinantes presentant des activites d'adipsine et de complement d

Publications (2)

Publication Number Publication Date
DK103091D0 DK103091D0 (da) 1991-05-30
DK103091A true DK103091A (da) 1991-07-30

Family

ID=23063108

Family Applications (1)

Application Number Title Priority Date Filing Date
DK103091A DK103091A (da) 1988-11-30 1991-05-30 Rekombinante proteiner med adipsin- og komplement d-aktiviteter

Country Status (9)

Country Link
US (1) US5223425A (fr)
JP (1) JPH04505098A (fr)
AU (1) AU4808190A (fr)
BR (1) BR8907798A (fr)
DK (1) DK103091A (fr)
FI (1) FI912586A0 (fr)
IL (1) IL92504A0 (fr)
WO (1) WO1990006365A1 (fr)
ZA (1) ZA899161B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08503852A (ja) * 1992-11-25 1996-04-30 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブハイヤー エデュケーション ヒト誘導性一酸化窒素シンターゼのｃＤＮＡクローンおよびその作製方法
US6310034B1 (en) 1993-05-21 2001-10-30 Ut-Battelle, Llc Agouti polypeptide compositions
US5789651A (en) * 1993-05-21 1998-08-04 Martin Marietta Energy Systems, Inc. Isolation and characterization of Agouti: a diabetes/obesity related gene
US6150152A (en) * 1993-05-28 2000-11-21 Washington University Human macrophage metalloelastase
US5869330A (en) * 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
US7737109B2 (en) * 2000-08-11 2010-06-15 Temple University Of The Commonwealth System Of Higher Education Obesity controlling method
AU2001284774A1 (en) * 2000-08-11 2002-02-25 Temple University Of The Commonwealth System Of Higher Education Obesity controlling method
US6867189B2 (en) * 2001-07-26 2005-03-15 Genset S.A. Use of adipsin/complement factor D in the treatment of metabolic related disorders
AU2003279084A1 (en) * 2002-09-25 2004-04-19 Genentech, Inc. Novel compositions and methods for the treatment of psoriasis
EP1578367A4 (fr) * 2002-11-01 2012-05-02 Genentech Inc Compositions et methodes pour le traitement de maladies liees au systeme immunitaire
WO2004047728A2 (fr) * 2002-11-26 2004-06-10 Genentech, Inc. Compositions et procedes destines au traitement de maladies de nature immune
WO2007141004A1 (fr) * 2006-06-09 2007-12-13 Bayer Healthcare Ag Utilisation de l'adipsine (adn) comme cible thérapeutique ou diagnostique
FR2966734B1 (fr) 2010-10-29 2014-07-18 Max Rombi Composition comprenant au moins une enzyme proteolytique pour son utilisation pour empecher la synthese des triglycerides
CN103760341B (zh) * 2014-01-28 2017-05-31 成都创宜生物科技有限公司 以Adipsin作为标志物制备检测工具的应用及检测工具
WO2015138309A1 (fr) 2014-03-13 2015-09-17 Dana-Farber Cancer Institute, Inc. Compositions et procédés de régultion de la fonction des cellules bêta pancréatiques à l'aide d'adipsine
EP4032543A1 (fr) * 2021-01-20 2022-07-27 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Peptides à partir de la séquence du facteur d du complément pour un usage médical, en particulier pour le traitement de maladies associées à l'ebv

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684623A (en) * 1985-05-02 1987-08-04 The Board Of Trustees Of The Cetus Corporation Use of tumor necrosis factor as a weight regulator

Also Published As

Publication number Publication date
FI912586A0 (fi) 1991-05-29
JPH04505098A (ja) 1992-09-10
US5223425A (en) 1993-06-29
WO1990006365A1 (fr) 1990-06-14
IL92504A0 (en) 1990-08-31
BR8907798A (pt) 1991-08-27
DK103091D0 (da) 1991-05-30
AU4808190A (en) 1990-06-26
ZA899161B (en) 1990-09-26

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