DK1030839T3 - Anvendelse af alkylerede iminosukkere til behandling af multidrugresistens - Google Patents
Anvendelse af alkylerede iminosukkere til behandling af multidrugresistensInfo
- Publication number
- DK1030839T3 DK1030839T3 DK98956449T DK98956449T DK1030839T3 DK 1030839 T3 DK1030839 T3 DK 1030839T3 DK 98956449 T DK98956449 T DK 98956449T DK 98956449 T DK98956449 T DK 98956449T DK 1030839 T3 DK1030839 T3 DK 1030839T3
- Authority
- DK
- Denmark
- Prior art keywords
- multidrug resistance
- imino sugars
- treat multidrug
- alkylated imino
- alkylated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6505197P | 1997-11-10 | 1997-11-10 | |
PCT/US1998/023239 WO1999024401A1 (en) | 1997-11-10 | 1998-11-09 | Use of alkylated iminosugars to treat multidrug resistance |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1030839T3 true DK1030839T3 (da) | 2004-05-03 |
Family
ID=22060028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK98956449T DK1030839T3 (da) | 1997-11-10 | 1998-11-09 | Anvendelse af alkylerede iminosukkere til behandling af multidrugresistens |
Country Status (15)
Country | Link |
---|---|
US (1) | US6225325B1 (zh) |
EP (1) | EP1030839B1 (zh) |
JP (1) | JP2001522833A (zh) |
AR (1) | AR018732A1 (zh) |
AT (1) | ATE258919T1 (zh) |
AU (1) | AU753336B2 (zh) |
CA (1) | CA2309321A1 (zh) |
DE (1) | DE69821520T2 (zh) |
DK (1) | DK1030839T3 (zh) |
ES (1) | ES2216327T3 (zh) |
MY (1) | MY122499A (zh) |
PT (1) | PT1030839E (zh) |
TW (1) | TW581677B (zh) |
WO (1) | WO1999024401A1 (zh) |
ZA (1) | ZA9810210B (zh) |
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AU761748B2 (en) | 1997-12-11 | 2003-06-12 | Chancellor, Masters And Scholars Of The University Of Oxford, The | Inhibition of membrane-associated viral replication |
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WO2000056334A1 (en) * | 1999-03-19 | 2000-09-28 | The Trustees Of Boston College | Use of imino sugars for anti-tumor therapy |
GB0100889D0 (en) | 2001-01-12 | 2001-02-21 | Oxford Glycosciences Uk Ltd | Compounds |
ES2302697T3 (es) | 1999-08-10 | 2008-08-01 | The Chancellor, Masters And Scholars Of The University Of Oxford | Compuestos n-alquilicos de cadena larga y derivados oxa de los mismos y uso como composiciones antivirales. |
US7256005B2 (en) | 1999-08-10 | 2007-08-14 | The Chancellor, Masters And Scholars Of The University Of Oxford | Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity |
GB0006539D0 (en) * | 2000-03-17 | 2000-05-10 | Oxford Glycosciences Uk Ltd | Therapies |
BR0213989A (pt) * | 2001-11-07 | 2005-03-01 | Pharmacia Corp | Métodos para promover a absorção e acúmulo nuclear de poliamidas em células eucarióticas |
ITMI20021040A1 (it) * | 2002-05-16 | 2003-11-17 | Novuspharma Spa | Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale |
US6982253B2 (en) * | 2002-06-05 | 2006-01-03 | Supergen, Inc. | Liquid formulation of decitabine and use of the same |
EP1534676B1 (en) | 2002-07-17 | 2012-09-12 | Actelion Pharmaceuticals Ltd. | Piperidinetriol derivatives as inhibitors of glycosylceramide synthase |
ES2393919T3 (es) | 2002-07-17 | 2013-01-02 | Actelion Pharmaceuticals Ltd. | Derivados de PIPERIDINETRIOL como inhibidores de GLUCOSILCERAMIDA SINTASA |
US7563810B2 (en) * | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
US8034831B2 (en) * | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
DK1594544T3 (en) * | 2003-01-31 | 2016-07-25 | Los Angeles Childrens Hospital | ORAL COMPOSITIONS OF FENRETINIDE WHICH HAVE INCREASED BIOTAILABILITY AND PROCEDURES FOR USING IT |
EP1597231A1 (en) * | 2003-02-20 | 2005-11-23 | Ranbaxy Laboratories, Ltd. | Derivatives of azasugars as anticancer agents |
GB0313677D0 (en) | 2003-06-13 | 2003-07-16 | Oxford Glycosciences Uk Ltd | Novel compound |
GB0313678D0 (en) | 2003-06-13 | 2003-07-16 | Oxford Glycosciences Uk Ltd | Novel compounds |
GB0400812D0 (en) * | 2004-01-14 | 2004-02-18 | Celltech R&D Ltd | Novel compounds |
GB0403165D0 (en) * | 2004-02-12 | 2004-03-17 | Ct | Novel uses for proton pump inhibitors |
WO2005123055A2 (en) * | 2004-06-14 | 2005-12-29 | Musc Foundation For Research Development | Methods for treating inflammatory disorders |
BRPI0612928A2 (pt) * | 2005-05-17 | 2010-12-07 | Amicus Therapeutics Inc | Método para aumentar a atividade de uma enzima de (alfa)-glucosidade em uma célula e método para tratar doença de pompe |
DOP2006000277A (es) | 2005-12-12 | 2007-08-31 | Bayer Pharmaceuticals Corp | Anticuerpos anti mn y métodos para su utilización |
JP5241709B2 (ja) | 2006-05-24 | 2013-07-17 | ユナイテッド セラピューティクス コーポレーション | デオキシノジリマイシンおよびd−アラビニトールのアナログおよび使用方法 |
EP2399587A1 (en) | 2006-08-02 | 2011-12-28 | The University of Oxford | Liposome treatment of viral infections |
US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
CA2719567A1 (en) * | 2008-03-26 | 2009-10-01 | University Of Oxford | Endoplasmic reticulum targeting liposomes |
US8703744B2 (en) | 2009-03-27 | 2014-04-22 | The Chancellor, Masters And Scholars Of The University Of Oxford | Cholesterol level lowering liposomes |
UY32560A (es) | 2009-04-29 | 2010-11-30 | Bayer Schering Pharma Ag | Inmunoconjugados de antimesotelina y usos de los mismos |
KR20230066482A (ko) | 2012-03-07 | 2023-05-15 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 폼페병의 치료를 위한 고농도 알파-글루코시다제 조성물 |
WO2014143999A1 (en) * | 2013-03-15 | 2014-09-18 | Unither Virology, Llc | Antibacterial compounds |
KR102455814B1 (ko) | 2014-09-30 | 2022-10-18 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 개선된 탄수화물을 가지는 고도로 강력한 산성 알파-글루코시다제 |
MX2018008185A (es) | 2015-12-30 | 2018-08-28 | Amicus Therapeutics Inc | Alfa-glucosidasa con mayor cantidad de acido para el tratamiento de la enfermedad de pompe. |
AU2017239641A1 (en) | 2016-03-30 | 2018-10-18 | Amicus Therapeutics, Inc. | Formulations comprising recombinant acid alpha-glucosidase |
WO2017173059A1 (en) | 2016-03-30 | 2017-10-05 | Amicus Therapeutics, Inc. | Method for selection of high m6p recombinant proteins |
EP4146624A4 (en) * | 2020-05-07 | 2024-05-29 | Alectos Therapeutics Inc | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF |
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-
1998
- 1998-11-09 WO PCT/US1998/023239 patent/WO1999024401A1/en active IP Right Grant
- 1998-11-09 DE DE69821520T patent/DE69821520T2/de not_active Expired - Fee Related
- 1998-11-09 MY MYPI98005087A patent/MY122499A/en unknown
- 1998-11-09 JP JP2000520415A patent/JP2001522833A/ja not_active Withdrawn
- 1998-11-09 DK DK98956449T patent/DK1030839T3/da active
- 1998-11-09 CA CA002309321A patent/CA2309321A1/en not_active Abandoned
- 1998-11-09 AT AT98956449T patent/ATE258919T1/de not_active IP Right Cessation
- 1998-11-09 PT PT98956449T patent/PT1030839E/pt unknown
- 1998-11-09 ES ES98956449T patent/ES2216327T3/es not_active Expired - Lifetime
- 1998-11-09 ZA ZA9810210A patent/ZA9810210B/xx unknown
- 1998-11-09 AU AU12973/99A patent/AU753336B2/en not_active Ceased
- 1998-11-09 EP EP98956449A patent/EP1030839B1/en not_active Expired - Lifetime
- 1998-11-10 US US09/189,177 patent/US6225325B1/en not_active Expired - Fee Related
- 1998-11-10 AR ARP980105672A patent/AR018732A1/es unknown
- 1998-12-11 TW TW087118629A patent/TW581677B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE258919T1 (de) | 2004-02-15 |
MY122499A (en) | 2006-04-29 |
JP2001522833A (ja) | 2001-11-20 |
DE69821520D1 (de) | 2004-03-11 |
AU753336B2 (en) | 2002-10-17 |
US6225325B1 (en) | 2001-05-01 |
WO1999024401A1 (en) | 1999-05-20 |
AU1297399A (en) | 1999-05-31 |
EP1030839B1 (en) | 2004-02-04 |
PT1030839E (pt) | 2004-05-31 |
AR018732A1 (es) | 2001-12-12 |
DE69821520T2 (de) | 2004-12-16 |
TW581677B (en) | 2004-04-01 |
ES2216327T3 (es) | 2004-10-16 |
EP1030839A1 (en) | 2000-08-30 |
CA2309321A1 (en) | 1999-05-20 |
ZA9810210B (en) | 1999-07-14 |
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