DK1021405T3 - Azetidinonderivater til behandling af HCMV-infektioner - Google Patents
Azetidinonderivater til behandling af HCMV-infektionerInfo
- Publication number
- DK1021405T3 DK1021405T3 DK98947256T DK98947256T DK1021405T3 DK 1021405 T3 DK1021405 T3 DK 1021405T3 DK 98947256 T DK98947256 T DK 98947256T DK 98947256 T DK98947256 T DK 98947256T DK 1021405 T3 DK1021405 T3 DK 1021405T3
- Authority
- DK
- Denmark
- Prior art keywords
- lower alkyl
- het
- hydrogen
- optionally substituted
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6154497P | 1997-10-07 | 1997-10-07 | |
| PCT/CA1998/000953 WO1999018072A1 (en) | 1997-10-07 | 1998-10-06 | Azetidinone derivatives for the treatment of hcmv infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1021405T3 true DK1021405T3 (da) | 2003-02-03 |
Family
ID=22036448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98947256T DK1021405T3 (da) | 1997-10-07 | 1998-10-06 | Azetidinonderivater til behandling af HCMV-infektioner |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6242439B1 (ja) |
| EP (1) | EP1021405B1 (ja) |
| JP (1) | JP2001519329A (ja) |
| AT (1) | ATE224872T1 (ja) |
| AU (1) | AU9426098A (ja) |
| CA (1) | CA2301543C (ja) |
| DE (1) | DE69808326T2 (ja) |
| DK (1) | DK1021405T3 (ja) |
| ES (1) | ES2180201T3 (ja) |
| PT (1) | PT1021405E (ja) |
| WO (1) | WO1999018072A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ304929B6 (cs) | 2001-03-28 | 2015-01-28 | Merck Sharp & Dohme Corp. | Enantioselektivní syntéza azetidinonových meziproduktů |
| DE10134478B4 (de) * | 2001-07-16 | 2007-10-31 | Priaton Gmbh | Verfahren zur Darstellung von thiazolsubstituierten β-Lactamen |
| WO2006098709A1 (en) * | 2005-03-09 | 2006-09-21 | Carrier Commercial Refrigeration, Inc. | Cold room with roof-top support platform |
| WO2010027951A1 (en) * | 2008-09-02 | 2010-03-11 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for inhibiting entry of a hepatic virus |
| KR102672512B1 (ko) | 2018-09-12 | 2024-06-10 | 노파르티스 아게 | 항바이러스 피리도피라진디온 화합물 |
| AU2020353055B2 (en) | 2019-09-26 | 2024-03-07 | Gilead Sciences, Inc. | Antiviral pyrazolopyridinone compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4680391A (en) | 1983-12-01 | 1987-07-14 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
| US5229381A (en) * | 1983-12-01 | 1993-07-20 | Merck & Co., Inc. | Substituted azetidinones as anti-inflammatory and antidegenerative agents |
| NZ228600A (en) * | 1988-04-11 | 1992-02-25 | Merck & Co Inc | 1-(benzylaminocarbonyl)-4-phenoxy-azetidin-2-one derivatives |
| DE377549T1 (de) | 1989-01-03 | 1990-11-08 | Marcos Y. Southbridge Mass. Kleinerman | Fernmessung physikalischer variablen mit faseroptischen systemen. |
| US5104862A (en) | 1991-03-20 | 1992-04-14 | Merck & Co., Inc. | Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone |
| US5100880A (en) | 1991-03-20 | 1992-03-31 | Merck & Co., Inc. | Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone |
| US5229831A (en) | 1991-09-20 | 1993-07-20 | The Charles Stark Draper Laboratory, Inc. | Ultraminiature tactical grade cryogenic RFOG |
| GB2266527A (en) | 1992-03-17 | 1993-11-03 | Merck & Co Inc | Substituted azetidinones useful in the treatment of leukemia |
| GB9314350D0 (en) * | 1993-07-12 | 1993-08-25 | Zeneca Ltd | Armide derivatives |
| BR9507165A (pt) * | 1994-03-23 | 1997-09-09 | Tokyo Tanase Company Limited | Inibidor da triptase clara agente terapêutico ou profilático para doenças virais processo terapêutico para doenças virais e uso da antileucoprotease |
-
1998
- 1998-10-06 ES ES98947256T patent/ES2180201T3/es not_active Expired - Lifetime
- 1998-10-06 AT AT98947256T patent/ATE224872T1/de active
- 1998-10-06 EP EP98947256A patent/EP1021405B1/en not_active Expired - Lifetime
- 1998-10-06 DK DK98947256T patent/DK1021405T3/da active
- 1998-10-06 US US09/167,143 patent/US6242439B1/en not_active Expired - Lifetime
- 1998-10-06 AU AU94260/98A patent/AU9426098A/en not_active Abandoned
- 1998-10-06 CA CA002301543A patent/CA2301543C/en not_active Expired - Fee Related
- 1998-10-06 DE DE69808326T patent/DE69808326T2/de not_active Expired - Lifetime
- 1998-10-06 WO PCT/CA1998/000953 patent/WO1999018072A1/en active IP Right Grant
- 1998-10-06 JP JP2000514884A patent/JP2001519329A/ja not_active Ceased
- 1998-10-06 PT PT98947256T patent/PT1021405E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001519329A (ja) | 2001-10-23 |
| EP1021405A1 (en) | 2000-07-26 |
| AU9426098A (en) | 1999-04-27 |
| WO1999018072A1 (en) | 1999-04-15 |
| DE69808326T2 (de) | 2003-05-22 |
| PT1021405E (pt) | 2003-02-28 |
| EP1021405B1 (en) | 2002-09-25 |
| ES2180201T3 (es) | 2003-02-01 |
| DE69808326D1 (de) | 2002-10-31 |
| US6242439B1 (en) | 2001-06-05 |
| ATE224872T1 (de) | 2002-10-15 |
| CA2301543A1 (en) | 1999-04-15 |
| CA2301543C (en) | 2005-05-17 |
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