DK0988534T3 - Elektroniske fremgangsmåder og apparat til detektering af analytter - Google Patents
Elektroniske fremgangsmåder og apparat til detektering af analytterInfo
- Publication number
- DK0988534T3 DK0988534T3 DK98930238.5T DK98930238T DK0988534T3 DK 0988534 T3 DK0988534 T3 DK 0988534T3 DK 98930238 T DK98930238 T DK 98930238T DK 0988534 T3 DK0988534 T3 DK 0988534T3
- Authority
- DK
- Denmark
- Prior art keywords
- detecting analytes
- electronic methods
- electronic
- methods
- analytes
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
- G01N33/5438—Electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Composite Materials (AREA)
- Inorganic Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4948997P | 1997-06-12 | 1997-06-12 | |
| PCT/US1998/012430 WO1998057159A1 (en) | 1997-06-12 | 1998-06-12 | Electronic methods for the detection of analytes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0988534T3 true DK0988534T3 (da) | 2011-05-23 |
Family
ID=21960096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98930238.5T DK0988534T3 (da) | 1997-06-12 | 1998-06-12 | Elektroniske fremgangsmåder og apparat til detektering af analytter |
Country Status (9)
| Country | Link |
|---|---|
| US (7) | US7560237B2 (enExample) |
| EP (1) | EP0988534B1 (enExample) |
| JP (1) | JP4124830B2 (enExample) |
| AT (1) | ATE498838T1 (enExample) |
| AU (1) | AU744503B2 (enExample) |
| CA (1) | CA2293744A1 (enExample) |
| DE (1) | DE69842134D1 (enExample) |
| DK (1) | DK0988534T3 (enExample) |
| WO (1) | WO1998057159A1 (enExample) |
Families Citing this family (129)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
| US6096273A (en) * | 1996-11-05 | 2000-08-01 | Clinical Micro Sensors | Electrodes linked via conductive oligomers to nucleic acids |
| US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US7899511B2 (en) | 2004-07-13 | 2011-03-01 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US9155496B2 (en) | 1997-03-04 | 2015-10-13 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US6013459A (en) | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
| CA2293744A1 (en) * | 1997-06-12 | 1998-12-17 | Clinical Micro Sensors, Inc. | Electronic methods for the detection of analytes |
| US7407811B2 (en) | 1997-12-22 | 2008-08-05 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using AC excitation |
| US7390667B2 (en) | 1997-12-22 | 2008-06-24 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using AC phase angle measurements |
| US7494816B2 (en) | 1997-12-22 | 2009-02-24 | Roche Diagnostic Operations, Inc. | System and method for determining a temperature during analyte measurement |
| JP2002500897A (ja) | 1998-01-27 | 2002-01-15 | クリニカル・マイクロ・センサーズ・インコーポレイテッド | 電子的核酸検出の増幅 |
| US6686150B1 (en) | 1998-01-27 | 2004-02-03 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8480580B2 (en) * | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) * | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| DE69939464D1 (de) | 1998-05-06 | 2008-10-16 | Clinical Micro Sensors Inc | Elekronische verfahren zur erkennung von analyten mit hilfe von einfachschichten |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
| US20050244954A1 (en) * | 1998-06-23 | 2005-11-03 | Blackburn Gary F | Binding acceleration techniques for the detection of analytes |
| US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| US6740518B1 (en) | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
| WO2000024941A1 (en) | 1998-10-27 | 2000-05-04 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| AU3128200A (en) * | 1998-12-30 | 2000-07-31 | Clinical Micro Sensors, Inc. | Tissue collection devices containing biosensors |
| US6432723B1 (en) | 1999-01-22 | 2002-08-13 | Clinical Micro Sensors, Inc. | Biosensors utilizing ligand induced conformation changes |
| US7312087B2 (en) | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US20020177135A1 (en) | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| US6942771B1 (en) * | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| WO2001054813A2 (en) * | 2000-01-11 | 2001-08-02 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US6326486B1 (en) | 1999-05-03 | 2001-12-04 | Gen-Probe Incorporated | Polynucleotide probes for detection and quantitation of bacteria in the family enterobacteriaceae |
| ATE330033T1 (de) | 1999-05-03 | 2006-07-15 | Gen Probe Inc | Polynukleotidsonden zur detektion und quantifizierung von actinomycetes |
| WO2000066788A2 (en) | 1999-05-03 | 2000-11-09 | Gen-Probe Incorporated | Polynucleotide probes for detection and quantitation of staphylococcus |
| US6821770B1 (en) | 1999-05-03 | 2004-11-23 | Gen-Probe Incorporated | Polynucleotide matrix-based method of identifying microorganisms |
| AU6360500A (en) * | 1999-07-20 | 2001-02-05 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| DE60041072D1 (de) * | 1999-07-26 | 2009-01-22 | Clinical Micro Sensors Inc | Em nachweis |
| US6361958B1 (en) * | 1999-11-12 | 2002-03-26 | Motorola, Inc. | Biochannel assay for hybridization with biomaterial |
| US20020034744A1 (en) * | 2000-03-27 | 2002-03-21 | Creager Stephen E. | Compositions and methods for detecting redox-active molecules in solution |
| US6753143B2 (en) | 2000-05-01 | 2004-06-22 | Clinical Micro Sensors, Inc. | Target analyte detection using asymmetrical self-assembled monolayers |
| JP4382265B2 (ja) * | 2000-07-12 | 2009-12-09 | 日本電気株式会社 | 酸化シリコン膜の形成方法及びその形成装置 |
| CA2427669A1 (en) * | 2000-11-03 | 2002-06-06 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| WO2002078512A2 (en) * | 2001-04-02 | 2002-10-10 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
| US6861224B2 (en) * | 2001-11-02 | 2005-03-01 | Fujitsu Limited | Protein detecting device |
| US8364229B2 (en) * | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
| GB0205455D0 (en) | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
| JP2006501449A (ja) | 2002-09-27 | 2006-01-12 | ザ ジェネラル ホスピタル コーポレーション | 細胞分離のためのマイクロ流体デバイスおよびその使用 |
| US7138121B2 (en) * | 2003-01-23 | 2006-11-21 | Spangler Brenda D | Biosensors utilizing dendrimer-immobilized ligands and there use thereof |
| US7488601B2 (en) | 2003-06-20 | 2009-02-10 | Roche Diagnostic Operations, Inc. | System and method for determining an abused sensor during analyte measurement |
| US7452457B2 (en) | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
| US7604721B2 (en) | 2003-06-20 | 2009-10-20 | Roche Diagnostics Operations, Inc. | System and method for coding information on a biosensor test strip |
| US7597793B2 (en) | 2003-06-20 | 2009-10-06 | Roche Operations Ltd. | System and method for analyte measurement employing maximum dosing time delay |
| GB0316075D0 (en) * | 2003-07-09 | 2003-08-13 | Molecular Sensing Plc | Protease detection assay |
| US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US7774145B2 (en) * | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| WO2006093505A2 (en) * | 2004-05-10 | 2006-09-08 | Northwestern University | Compositions and methods for analyte detection |
| US7569126B2 (en) | 2004-06-18 | 2009-08-04 | Roche Diagnostics Operations, Inc. | System and method for quality assurance of a biosensor test strip |
| US7556723B2 (en) | 2004-06-18 | 2009-07-07 | Roche Diagnostics Operations, Inc. | Electrode design for biosensor |
| US9414777B2 (en) | 2004-07-13 | 2016-08-16 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8133178B2 (en) | 2006-02-22 | 2012-03-13 | Dexcom, Inc. | Analyte sensor |
| US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
| US7935309B2 (en) * | 2005-04-15 | 2011-05-03 | Worcester Polytechnic Institute | Multi-transduction mechanism based microfluidic analyte sensors |
| AR054851A1 (es) | 2005-07-20 | 2007-07-18 | Bayer Healthcare Llc | Amperometria regulada |
| US8921102B2 (en) | 2005-07-29 | 2014-12-30 | Gpb Scientific, Llc | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
| WO2007037341A1 (ja) * | 2005-09-29 | 2007-04-05 | Toto Ltd. | 光電流を用いた被検物質の特異的検出方法、それに用いられる電極、測定用セルおよび測定装置 |
| US9757061B2 (en) | 2006-01-17 | 2017-09-12 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US20080071158A1 (en) * | 2006-06-07 | 2008-03-20 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
| US20080050739A1 (en) | 2006-06-14 | 2008-02-28 | Roland Stoughton | Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats |
| EP2589668A1 (en) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Rare cell analysis using sample splitting and DNA tags |
| JP4321599B2 (ja) * | 2007-02-06 | 2009-08-26 | セイコーエプソン株式会社 | 検出素子 |
| JP4301316B2 (ja) * | 2007-03-30 | 2009-07-22 | ダイキン工業株式会社 | スクロール部材及びその製造方法、並びに圧縮機構及びスクロール圧縮機 |
| US20200037875A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US8197650B2 (en) | 2007-06-07 | 2012-06-12 | Sensor Innovations, Inc. | Silicon electrochemical sensors |
| US20080306434A1 (en) | 2007-06-08 | 2008-12-11 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| EP4468309A3 (en) | 2007-10-09 | 2024-12-11 | DexCom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| US8951400B2 (en) | 2007-10-17 | 2015-02-10 | Ohmx Corporation | Chemistry used in biosensors |
| AU2008311820A1 (en) * | 2007-10-17 | 2009-04-23 | Ohmx Corporation | Novel chemistry used in biosensors |
| US8417312B2 (en) | 2007-10-25 | 2013-04-09 | Dexcom, Inc. | Systems and methods for processing sensor data |
| WO2009061941A2 (en) | 2007-11-06 | 2009-05-14 | Osmetech Molecular Diagnostics | Baseless nucleotide analogues and uses thereof |
| US9839395B2 (en) | 2007-12-17 | 2017-12-12 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US9143569B2 (en) * | 2008-02-21 | 2015-09-22 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US9250234B2 (en) | 2011-01-19 | 2016-02-02 | Ohmx Corporation | Enzyme triggered redox altering chemical elimination (E-TRACE) immunoassay |
| WO2011034668A1 (en) | 2009-08-07 | 2011-03-24 | Ohmx Corporation | Enzyme triggered redox altering chemical elimination (e-trace) immunoassay |
| JP2011232328A (ja) * | 2010-04-09 | 2011-11-17 | Hitachi Ltd | 生体物質検出アレイ、計測装置および計測方法 |
| EP2571997A2 (en) | 2010-05-21 | 2013-03-27 | Ohmx Corporation | Enzymatic activity of psa as diagnostic marker for prostate cancer |
| US9176092B2 (en) * | 2010-06-11 | 2015-11-03 | Labmaster Oy | Integrated carbon electrode chips for the electric excitation of lanthanide chelates, and analytical methods using these chips |
| WO2012083258A2 (en) | 2010-12-16 | 2012-06-21 | Sensor Innovations, Inc. | Electrochemical sensors |
| JP6203183B2 (ja) | 2011-10-17 | 2017-09-27 | オームクス コーポレイション | 酵素誘発レドックス変化化学的脱離(e−trace)イムノアッセイを使用する、ヘモグロビンa1cのパーセンテージの単回直接検出 |
| CA2854459A1 (en) | 2011-11-04 | 2013-05-10 | Ohmx Corporation | Novel chemistry used in biosensors |
| CA2860739A1 (en) | 2012-01-09 | 2013-07-18 | Ohmx Corporation | Enzyme cascade methods for e-trace assay signal amplification |
| US9048431B2 (en) | 2012-05-07 | 2015-06-02 | California Instistute Of Technology | Electronic devices employing aligned organic polymers |
| WO2014018899A1 (en) | 2012-07-27 | 2014-01-30 | Ohmx Corporation | Electric measurement of monolayers following pro-cleave detection of presence and activity of enzymes and other target analytes |
| US9404883B2 (en) | 2012-07-27 | 2016-08-02 | Ohmx Corporation | Electronic measurements of monolayers following homogeneous reactions of their components |
| US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
| CA2889415C (en) | 2012-10-24 | 2020-06-02 | Genmark Diagnostics, Inc. | Integrated multiplex target analysis |
| EP3034171B1 (en) | 2013-03-15 | 2019-04-24 | Genmark Diagnostics Inc. | Systems, methods and apparatus for manipulating deformable fluid vessels |
| GB201314402D0 (en) | 2013-08-12 | 2013-09-25 | Isis Innovation | Capacitance Spectroscopic Method and Electrode |
| EP3047274A2 (en) | 2013-09-20 | 2016-07-27 | Ohmx Corporation | Psa enzymatic activity: a new biomarker for assessing prostate cancer aggressiveness |
| US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
| USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
| US9470634B1 (en) * | 2013-12-10 | 2016-10-18 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Electride mediated surface enhanced Raman scattering (SERS) |
| US9880121B2 (en) | 2014-04-29 | 2018-01-30 | Ohmx Corporation | Bioelectronic binding assay using peak profiling |
| US20160041118A1 (en) | 2014-08-11 | 2016-02-11 | Ohmx Corporation | Enzyme triggered redox altering chemical elimination (e-trace) assay with multiplexing capabilities |
| ES3038141T3 (en) | 2014-11-11 | 2025-10-09 | Hoffmann La Roche | Fluid sample processing cartridge |
| US9598722B2 (en) | 2014-11-11 | 2017-03-21 | Genmark Diagnostics, Inc. | Cartridge for performing assays in a closed sample preparation and reaction system |
| US10005080B2 (en) | 2014-11-11 | 2018-06-26 | Genmark Diagnostics, Inc. | Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation |
| US10883000B1 (en) * | 2016-03-09 | 2021-01-05 | The Regents Of The University Of California | Chemically modified surfaces with self-assembled aromatic functionalities |
| WO2018053501A1 (en) | 2016-09-19 | 2018-03-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
| US20190062809A1 (en) | 2017-08-24 | 2019-02-28 | Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.) | Electrochemical detection of bacterial and/or fungal infections |
| EP3673086B1 (en) | 2017-08-24 | 2025-04-09 | Roche Diagnostics GmbH | Electrochemical detection of bacterial and/or fungal infections |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| JP2021500162A (ja) | 2017-10-24 | 2021-01-07 | デックスコム・インコーポレーテッド | 事前接続された分析物センサ |
| CA3193808A1 (en) * | 2020-09-24 | 2022-03-31 | Jason Heikenfeld | Small volume aptamer sensing without solution impedance or analyte depletion |
| US20240027392A1 (en) * | 2020-09-24 | 2024-01-25 | University Of Cincinnati | Solute-phase electrochemical aptamer sensors for improved longevity and sensitivity |
| CA3248040A1 (en) | 2022-01-13 | 2023-07-20 | Canary Medical Switzerland Ag | ANALYTICAL AND ENVIRONMENTAL SENSORS |
Family Cites Families (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5078830A (enExample) * | 1973-11-16 | 1975-06-26 | ||
| SE407115B (sv) * | 1975-10-06 | 1979-03-12 | Kabi Ab | Forfarande och metelektroder for studium av enzymatiska och andra biokemiska reaktioner |
| US4819658A (en) * | 1982-02-11 | 1989-04-11 | American Telephone And Telegraph Company, At&T Bell Laboratories | Method and apparatus for measuring the temperature profile of a surface |
| US4713347A (en) * | 1985-01-14 | 1987-12-15 | Sensor Diagnostics, Inc. | Measurement of ligand/anti-ligand interactions using bulk conductance |
| US4735907A (en) * | 1985-03-18 | 1988-04-05 | Eastman Kodak Company | Stabilized fluorescent rare earth labels and labeled physiologically reactive species |
| EP0213825A3 (en) * | 1985-08-22 | 1989-04-26 | Molecular Devices Corporation | Multiple chemically modulated capacitance |
| US5192507A (en) * | 1987-06-05 | 1993-03-09 | Arthur D. Little, Inc. | Receptor-based biosensors |
| GB2217447A (en) | 1988-04-21 | 1989-10-25 | Atomic Energy Authority Uk | Bonding to metal surfaces |
| US4920047A (en) * | 1988-05-20 | 1990-04-24 | General Electric Company | Electrical detection of the immune reaction |
| SE462454B (sv) * | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5200051A (en) * | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
| US5874316A (en) * | 1989-01-27 | 1999-02-23 | Australian Membrane Biotechnology Research Institute | Receptor membranes and ionophore gating |
| US5089112A (en) * | 1989-03-20 | 1992-02-18 | Associated Universities, Inc. | Electrochemical biosensor based on immobilized enzymes and redox polymers |
| US4964972A (en) * | 1989-03-30 | 1990-10-23 | Yeda Research And Development Company Limited | Ionic recognition and selective response in self assembling monolayer membranes on electrodes |
| US5156810A (en) * | 1989-06-15 | 1992-10-20 | Biocircuits Corporation | Biosensors employing electrical, optical and mechanical signals |
| US5491097A (en) * | 1989-06-15 | 1996-02-13 | Biocircuits Corporation | Analyte detection with multilayered bioelectronic conductivity sensors |
| US5320725A (en) * | 1989-08-02 | 1994-06-14 | E. Heller & Company | Electrode and method for the detection of hydrogen peroxide |
| US5262035A (en) * | 1989-08-02 | 1993-11-16 | E. Heller And Company | Enzyme electrodes |
| US5324457A (en) * | 1989-10-02 | 1994-06-28 | Board Of Regents, The University Of Tx System | Devices and methods for generating electrogenerated chemiluminescence |
| EP0712139A3 (en) * | 1990-01-31 | 1998-03-25 | Fujikura Ltd. | Electric insulated wire and cable using the same |
| GB2244135B (en) * | 1990-05-04 | 1994-07-13 | Gen Electric Co Plc | Sensor devices |
| US5108573A (en) | 1990-06-05 | 1992-04-28 | The United States Of America As Represented By The United States Department Of Energy | Morphology in electrochemically grown conducting polymer films |
| US5763191A (en) * | 1990-12-12 | 1998-06-09 | Boehringer Mannheim Gmbh | Universal binding film |
| US5180968A (en) * | 1991-03-01 | 1993-01-19 | Research Foundation Of State University Of New York | Method and apparatus for compensation of double layer charging current in electrochemical cells |
| JPH04278450A (ja) * | 1991-03-04 | 1992-10-05 | Adam Heller | バイオセンサー及び分析物を分析する方法 |
| US5171853A (en) | 1991-08-05 | 1992-12-15 | North Carolina State University | Process of cleaving nucleic acids with oxoruthenium(IV) complexes |
| US5187096A (en) * | 1991-08-08 | 1993-02-16 | Rensselaer Polytechnic Institute | Cell substrate electrical impedance sensor with multiple electrode array |
| US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
| US5632957A (en) * | 1993-11-01 | 1997-05-27 | Nanogen | Molecular biological diagnostic systems including electrodes |
| US5846708A (en) | 1991-11-19 | 1998-12-08 | Massachusetts Institiute Of Technology | Optical and electrical methods and apparatus for molecule detection |
| US5391272A (en) * | 1992-03-06 | 1995-02-21 | Andcare, Inc. | Electrochemical immunoassay methods |
| IL102930A (en) * | 1992-08-25 | 1997-03-18 | Yissum Res Dev Co | Electrobiochemical analytical method and electrodes |
| CA2157503A1 (en) * | 1993-03-05 | 1994-09-15 | John M. Riviello | Pulsed electrochemical detection using polymer electroactive electrodes |
| US5952172A (en) * | 1993-12-10 | 1999-09-14 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5824473A (en) | 1993-12-10 | 1998-10-20 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US6071699A (en) * | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| IL108726A (en) * | 1994-02-22 | 1999-12-31 | Yissum Res Dev Co | Electrobiochemical method and system for the determination of an analyte which is a member of a recognition pair in a liquid medium and electrodes therefor |
| US5780324A (en) | 1994-03-30 | 1998-07-14 | Denso Corporation | Method of manufacturing a vertical semiconductor device |
| US5824483A (en) | 1994-05-18 | 1998-10-20 | Pence Inc. | Conformationally-restricted combinatiorial library composition and method |
| US5506420A (en) * | 1994-09-14 | 1996-04-09 | The Regents Of The University Of California | Semiconductor bio-electronic devices incorporating biochemical stabilization layers |
| US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
| DE4442253A1 (de) * | 1994-11-28 | 1996-05-30 | Bayer Corp N D Ges D Staates I | Elektrochemischer Enzymbiosensor |
| CZ299135B6 (cs) * | 1995-03-10 | 2008-04-30 | Meso Scale Technologies, Llc. Corporation Servicecompany | Kazeta a zarízení pro použití pri detekci analytu, zpusob provádení testu za použití uvedené kazety, kit pro použití pri provádení množiny elektrochemiluminescencních testu a zpusob detekce nebo merení analytu |
| US5534132A (en) * | 1995-05-04 | 1996-07-09 | Vreeke; Mark | Electrode and method for the detection of an affinity reaction |
| US5972199A (en) * | 1995-10-11 | 1999-10-26 | E. Heller & Company | Electrochemical analyte sensors using thermostable peroxidase |
| CA2255952A1 (en) | 1996-05-22 | 1997-11-27 | Australian Membrane And Biotechnology Research Institute | Nucleic acid sensor |
| US6096273A (en) * | 1996-11-05 | 2000-08-01 | Clinical Micro Sensors | Electrodes linked via conductive oligomers to nucleic acids |
| US7160678B1 (en) * | 1996-11-05 | 2007-01-09 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| US7014992B1 (en) * | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| US7045285B1 (en) * | 1996-11-05 | 2006-05-16 | Clinical Micro Sensors, Inc. | Electronic transfer moieties attached to peptide nucleic acids |
| US7381525B1 (en) * | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US6060327A (en) * | 1997-05-14 | 2000-05-09 | Keensense, Inc. | Molecular wire injection sensors |
| US6013459A (en) * | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
| CA2293744A1 (en) * | 1997-06-12 | 1998-12-17 | Clinical Micro Sensors, Inc. | Electronic methods for the detection of analytes |
| US5922183A (en) * | 1997-06-23 | 1999-07-13 | Eic Laboratories, Inc. | Metal oxide matrix biosensors |
| US6063573A (en) * | 1998-01-27 | 2000-05-16 | Clinical Micro Sensors, Inc. | Cycling probe technology using electron transfer detection |
| US6686150B1 (en) * | 1998-01-27 | 2004-02-03 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| JP2002500897A (ja) * | 1998-01-27 | 2002-01-15 | クリニカル・マイクロ・センサーズ・インコーポレイテッド | 電子的核酸検出の増幅 |
| DE69939464D1 (de) * | 1998-05-06 | 2008-10-16 | Clinical Micro Sensors Inc | Elekronische verfahren zur erkennung von analyten mit hilfe von einfachschichten |
| US20030087228A1 (en) | 1998-05-06 | 2003-05-08 | Cynthia Bamdad | Electronic detection of nucleic acids using monolayers |
| US6269150B1 (en) * | 1998-06-11 | 2001-07-31 | Lucent Technologies, Inc. | Reliable, unattended, automated testing system and method for complex telecommunication systems |
| US6290839B1 (en) * | 1998-06-23 | 2001-09-18 | Clinical Micro Sensors, Inc. | Systems for electrophoretic transport and detection of analytes |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
| US6761816B1 (en) * | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| US6740518B1 (en) * | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
| WO2000024941A1 (en) * | 1998-10-27 | 2000-05-04 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| US20040053290A1 (en) * | 2000-01-11 | 2004-03-18 | Terbrueggen Robert Henry | Devices and methods for biochip multiplexing |
| US7312087B2 (en) * | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US6942771B1 (en) * | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| US6753143B2 (en) * | 2000-05-01 | 2004-06-22 | Clinical Micro Sensors, Inc. | Target analyte detection using asymmetrical self-assembled monolayers |
| CA2444186A1 (en) * | 2001-04-03 | 2002-10-03 | Clinical Micro Sensors, Inc. | Nucleic acid reactions using labels with different redox potentials |
| US7658700B2 (en) * | 2004-08-09 | 2010-02-09 | Tate Maloy | Training device for exercising muscle groups of the entire body |
-
1998
- 1998-06-12 CA CA002293744A patent/CA2293744A1/en not_active Abandoned
- 1998-06-12 WO PCT/US1998/012430 patent/WO1998057159A1/en not_active Ceased
- 1998-06-12 AU AU79678/98A patent/AU744503B2/en not_active Ceased
- 1998-06-12 AT AT98930238T patent/ATE498838T1/de not_active IP Right Cessation
- 1998-06-12 DK DK98930238.5T patent/DK0988534T3/da active
- 1998-06-12 JP JP50332599A patent/JP4124830B2/ja not_active Expired - Lifetime
- 1998-06-12 EP EP98930238A patent/EP0988534B1/en not_active Expired - Lifetime
- 1998-06-12 US US09/096,593 patent/US7560237B2/en not_active Expired - Fee Related
- 1998-06-12 DE DE69842134T patent/DE69842134D1/de not_active Expired - Lifetime
-
2007
- 2007-10-30 US US11/981,645 patent/US7601507B2/en not_active Expired - Fee Related
- 2007-10-30 US US11/981,735 patent/US7713711B2/en not_active Expired - Fee Related
-
2009
- 2009-02-05 US US12/366,471 patent/US7759073B2/en not_active Expired - Fee Related
-
2010
- 2010-05-04 US US12/773,382 patent/US8114661B2/en not_active Expired - Fee Related
-
2012
- 2012-02-03 US US13/366,068 patent/US8383356B2/en not_active Expired - Fee Related
-
2013
- 2013-01-31 US US13/756,257 patent/US8741585B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU744503B2 (en) | 2002-02-28 |
| US20110059535A1 (en) | 2011-03-10 |
| US7560237B2 (en) | 2009-07-14 |
| AU7967898A (en) | 1998-12-30 |
| US20020009810A1 (en) | 2002-01-24 |
| US8114661B2 (en) | 2012-02-14 |
| US8741585B2 (en) | 2014-06-03 |
| US7601507B2 (en) | 2009-10-13 |
| EP0988534A1 (en) | 2000-03-29 |
| CA2293744A1 (en) | 1998-12-17 |
| EP0988534B1 (en) | 2011-02-16 |
| DE69842134D1 (de) | 2011-03-31 |
| US7759073B2 (en) | 2010-07-20 |
| US20090242430A1 (en) | 2009-10-01 |
| US7713711B2 (en) | 2010-05-11 |
| US20120199499A1 (en) | 2012-08-09 |
| JP2001514762A (ja) | 2001-09-11 |
| US20130220832A1 (en) | 2013-08-29 |
| US20080237061A1 (en) | 2008-10-02 |
| ATE498838T1 (de) | 2011-03-15 |
| JP4124830B2 (ja) | 2008-07-23 |
| US8383356B2 (en) | 2013-02-26 |
| WO1998057159A1 (en) | 1998-12-17 |
| US20090173640A1 (en) | 2009-07-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0988534T3 (da) | Elektroniske fremgangsmåder og apparat til detektering af analytter | |
| DK0823636T3 (da) | Apparat til måling af koncentrationen af en analyt med fjerndosering | |
| DK1058769T3 (da) | Apparat til færdiggörelse af en underjordisk brönd og fremgangsmåde til anvendelse af samme | |
| DE69612017D1 (de) | Emulsion zur robusten erfassung von gasen | |
| NO983366D0 (no) | FremgangsmÕte og anordning for bestemmelse av banen til borehull | |
| ATE289684T1 (de) | Vorrichtung und apparat zur gleichzeitigen detektion von mehreren analyten | |
| EP1318399A3 (en) | Passive sample detection to initiate timing of an assay | |
| DK1047943T3 (da) | Anordning til chromatografisk afprøvning af fremgangsmåde til påvisning af nærværelse af en analyt i en blodprøve | |
| DK1372469T3 (da) | Fremgangsmåde til bestemmelse af de optiske egenskaber af et flerlaget væv | |
| DK0770854T3 (da) | Fremgangsmåde, apparat og system til bestemmelse af prøver | |
| DK0645015T3 (da) | Forbedringer ved eller i forbindelse med analytpåvisning. | |
| DK0959333T3 (da) | Fremgangsmåde til detektering af vibrationsbölge og vibrationsbölgedetektor | |
| DE60008256D1 (de) | Kohlenmonoxidsensor | |
| ATE347611T1 (de) | Automatischer apparat zum messen von wassertoxizität | |
| NO20004434L (no) | Apparat for innstrømningsdeteksjon og system for anvendelse derav | |
| DK0734461T3 (da) | Anvendelse af et apparat til dannelse af exciteret gas | |
| DE69736313D1 (de) | Einrichtung zur Gaskonzentrationsdetektion | |
| CY1105025T1 (el) | Αναλυση λεπτινης βασιζομενη στην ανιχνευση εκφρασης ang-2 | |
| FI973561A0 (fi) | Menetelmä ja yhdisteitä analysoitavien aineiden määrittämiseksi remanenssimittausten avulla ja mainittujen yhdisteiden käyttö | |
| DK1664747T3 (da) | Fremgangsmåde og indretning til påvisning af meget små partikelmængder | |
| NO20002541D0 (no) | FremgangsmÕte og apparatur for Õ bestemme et arrangement av komponenter | |
| NO995710D0 (no) | Fremgangsmåte og apparat for deteksjon av modulasjon | |
| DE69424234D1 (de) | Vorrichtung zum Nachweis eines Analyten | |
| DK0714023T3 (da) | Fremgangsmåde og indretning til bestemmelse af kulindholdet i aske | |
| FI960534L (fi) | Menetelmä analyyttien ei-kilpailevaa määritystä varten |