DK0922703T3 - Substituerede heterocykliske benzocycloalkener og disses anvendelse som analgetisk virksomme stoffer - Google Patents

Substituerede heterocykliske benzocycloalkener og disses anvendelse som analgetisk virksomme stoffer

Info

Publication number
DK0922703T3
DK0922703T3 DK98122218T DK98122218T DK0922703T3 DK 0922703 T3 DK0922703 T3 DK 0922703T3 DK 98122218 T DK98122218 T DK 98122218T DK 98122218 T DK98122218 T DK 98122218T DK 0922703 T3 DK0922703 T3 DK 0922703T3
Authority
DK
Denmark
Prior art keywords
active substances
substituted heterocyclic
analgesically active
benzocycloalkenes
heterocyclic benzocycloalkenes
Prior art date
Application number
DK98122218T
Other languages
Danish (da)
English (en)
Inventor
Oswald Dr Zimmer
Wolfgang Prof Dr Strassburger
Claudia Dr Puetz
Werner Dr Englberger
Babette-Yvonne Dr Koegel
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of DK0922703T3 publication Critical patent/DK0922703T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/08Naphthothiopyrans; Hydrogenated naphthothiopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D337/00Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02Seven-membered rings
    • C07D337/06Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
DK98122218T 1997-12-13 1998-11-23 Substituerede heterocykliske benzocycloalkener og disses anvendelse som analgetisk virksomme stoffer DK0922703T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19755480A DE19755480A1 (de) 1997-12-13 1997-12-13 Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen

Publications (1)

Publication Number Publication Date
DK0922703T3 true DK0922703T3 (da) 2003-03-17

Family

ID=7851818

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98122218T DK0922703T3 (da) 1997-12-13 1998-11-23 Substituerede heterocykliske benzocycloalkener og disses anvendelse som analgetisk virksomme stoffer

Country Status (29)

Country Link
US (1) US6013809A (hu)
EP (1) EP0922703B1 (hu)
JP (1) JPH11246547A (hu)
KR (1) KR19990062982A (hu)
CN (1) CN100376564C (hu)
AR (1) AR017800A1 (hu)
AT (1) ATE229016T1 (hu)
AU (1) AU747979B2 (hu)
BR (1) BR9805437A (hu)
CA (1) CA2256007C (hu)
CO (1) CO4990950A1 (hu)
CZ (1) CZ294990B6 (hu)
DE (2) DE19755480A1 (hu)
DK (1) DK0922703T3 (hu)
ES (1) ES2189072T3 (hu)
HK (1) HK1020944A1 (hu)
HU (1) HU226014B1 (hu)
IL (1) IL127518A (hu)
MY (1) MY133169A (hu)
NO (1) NO985818L (hu)
NZ (1) NZ332622A (hu)
PE (1) PE133499A1 (hu)
PL (1) PL194934B1 (hu)
PT (1) PT922703E (hu)
RU (1) RU2197484C2 (hu)
SI (1) SI0922703T1 (hu)
SK (1) SK283366B6 (hu)
UY (1) UY25296A1 (hu)
ZA (1) ZA9811346B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DE19830105C1 (de) * 1998-07-06 2000-02-17 Gruenenthal Gmbh Acridinderivate
WO2000010965A2 (en) 1998-08-20 2000-03-02 Takeda Chemical Industries, Ltd. Quaternary ammonium salts and their use as anti-hiv agents
DE10033459A1 (de) * 2000-07-10 2002-01-24 Gruenenthal Gmbh Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel
US7289083B1 (en) * 2000-11-30 2007-10-30 Palm, Inc. Multi-sided display for portable computer
BRPI0911622B8 (pt) * 2008-04-28 2021-05-25 Janssen Pharmaceutica Nv derivados de benzoxepina e benzociclo-heptano, seu processo de preparação, seu uso e composição farmacêutica que os compreende
CN104023727B (zh) 2011-10-28 2017-04-05 鲁美纳医药公司 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂
CN104844471B (zh) * 2015-04-21 2017-05-03 苏州远智医药科技有限公司 一种作为dor受体拮抗剂的化合物
CN109896991B (zh) * 2017-12-08 2020-11-20 苏州远智医药科技有限公司 一种δ阿片受体拮抗剂及其用途和药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3444176A (en) * 1967-04-28 1969-05-13 Mcneilab Inc Certain 4-diloweralkylamino-lower alkyl - 5 - pyridyl (or phenyl)-2,3-dihydro - 1 - benzothiepins and derivatives thereof
US4104280A (en) * 1977-02-04 1978-08-01 Syntex (U.S.A.) Inc. Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives
JPS61130286A (ja) * 1984-11-28 1986-06-18 Suntory Ltd 2,3−ジヒドロ−1−ベンズオキセピン誘導体
JP3042156B2 (ja) * 1992-02-20 2000-05-15 田辺製薬株式会社 ナフタレン誘導体、その製法及びその合成中間体
DE69315920T2 (de) * 1992-09-04 1998-06-10 Takeda Chemical Industries Ltd Kondensierte heterozyklische Verbindungen, deren Herstellung und Verwendung

Also Published As

Publication number Publication date
ZA9811346B (en) 1999-06-14
HU9802886D0 (en) 1999-02-01
PL330257A1 (en) 1999-06-21
CA2256007C (en) 2009-04-14
CA2256007A1 (en) 1999-06-13
EP0922703A1 (de) 1999-06-16
HK1020944A1 (en) 2000-05-26
SI0922703T1 (en) 2003-04-30
MY133169A (en) 2007-10-31
PT922703E (pt) 2003-04-30
RU2197484C2 (ru) 2003-01-27
KR19990062982A (ko) 1999-07-26
CZ294990B6 (cs) 2005-04-13
IL127518A (en) 2003-05-29
PE133499A1 (es) 2000-02-02
PL194934B1 (pl) 2007-07-31
SK283366B6 (sk) 2003-06-03
UY25296A1 (es) 2001-05-31
CO4990950A1 (es) 2000-12-26
DE19755480A1 (de) 1999-06-24
EP0922703B1 (de) 2002-12-04
JPH11246547A (ja) 1999-09-14
CN1221743A (zh) 1999-07-07
HUP9802886A2 (hu) 2001-04-28
HU226014B1 (en) 2008-02-28
AR017800A1 (es) 2001-10-24
BR9805437A (pt) 2000-05-02
CN100376564C (zh) 2008-03-26
NO985818D0 (no) 1998-12-11
SK169998A3 (en) 1999-07-12
ES2189072T3 (es) 2003-07-01
US6013809A (en) 2000-01-11
HUP9802886A3 (en) 2001-09-28
ATE229016T1 (de) 2002-12-15
NO985818L (no) 1999-06-14
NZ332622A (en) 2000-03-27
AU9707398A (en) 1999-07-01
DE59806523D1 (de) 2003-01-16
AU747979B2 (en) 2002-05-30
IL127518A0 (en) 1999-10-28
CZ407698A3 (cs) 1999-06-16

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