DK0904110T3 - Nitrogenoxid-afgivende sammensætninger til nedsættelse af lægemidlers toksicitet - Google Patents

Nitrogenoxid-afgivende sammensætninger til nedsættelse af lægemidlers toksicitet

Info

Publication number
DK0904110T3
DK0904110T3 DK97906115T DK97906115T DK0904110T3 DK 0904110 T3 DK0904110 T3 DK 0904110T3 DK 97906115 T DK97906115 T DK 97906115T DK 97906115 T DK97906115 T DK 97906115T DK 0904110 T3 DK0904110 T3 DK 0904110T3
Authority
DK
Denmark
Prior art keywords
nitric oxide
drug toxicity
reduce drug
releasing compositions
compositions
Prior art date
Application number
DK97906115T
Other languages
Danish (da)
English (en)
Inventor
Soldato Piero Del
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11373387&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0904110(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nicox Sa filed Critical Nicox Sa
Application granted granted Critical
Publication of DK0904110T3 publication Critical patent/DK0904110T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Underground Structures, Protecting, Testing And Restoring Foundations (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK97906115T 1996-02-26 1997-02-24 Nitrogenoxid-afgivende sammensætninger til nedsættelse af lægemidlers toksicitet DK0904110T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI000352A IT1282686B1 (it) 1996-02-26 1996-02-26 Composti in grado di ridurre la tossicita' da farmaci
PCT/EP1997/000873 WO1997031654A1 (en) 1996-02-26 1997-02-24 Nitric oxide donors capable of reducing toxicity from drugs

Publications (1)

Publication Number Publication Date
DK0904110T3 true DK0904110T3 (da) 2002-11-11

Family

ID=11373387

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97906115T DK0904110T3 (da) 1996-02-26 1997-02-24 Nitrogenoxid-afgivende sammensætninger til nedsættelse af lægemidlers toksicitet

Country Status (16)

Country Link
US (1) US7087588B2 (esLanguage)
EP (2) EP1221326A3 (esLanguage)
JP (1) JP2000506133A (esLanguage)
KR (1) KR19990087113A (esLanguage)
AT (1) ATE220920T1 (esLanguage)
AU (1) AU706591B2 (esLanguage)
BR (1) BR9707739A (esLanguage)
CA (1) CA2247848C (esLanguage)
DE (1) DE69714253T2 (esLanguage)
DK (1) DK0904110T3 (esLanguage)
ES (1) ES2180938T3 (esLanguage)
HU (1) HUP9900993A3 (esLanguage)
IT (1) IT1282686B1 (esLanguage)
PT (1) PT904110E (esLanguage)
RU (1) RU2192247C2 (esLanguage)
WO (1) WO1997031654A1 (esLanguage)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043232A (en) * 1997-07-23 2000-03-28 Nitromed, Inc. Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
GB9801398D0 (en) 1998-01-22 1998-03-18 Anggard Erik E Chemical compounds
IT1298338B1 (it) * 1998-03-05 1999-12-20 Nicox Sa Composizioni farmaceutiche per l'ulcera
EP1126838A4 (en) 1998-10-30 2005-02-16 Nitromed Inc NITROSIS AND NITROSYAL NON-STEROID ANTI-INFLAMMATORY COMPOUNDS, COMPOSITIONS AND METHODS OF USE
TWI243672B (en) * 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
CA2393724A1 (en) 1999-12-23 2001-06-28 Nitromed, Inc. Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
US7018979B1 (en) 2000-01-26 2006-03-28 Cedars-Sinai Medical Center Method for using potassium channel agonists for delivering a medicant to an abnormal brain region and/or a malignant tumor
JP2003523965A (ja) * 2000-01-26 2003-08-12 シーダース シナイ メディカル センター 異常な脳領域および／または悪性腫瘍に薬剤をデリバリーするためにカリウムチャンネルアゴニストを使用する方法
CA2432642A1 (en) 2000-12-21 2002-08-08 Subhash P. Khanapure Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
EP1219306A1 (en) * 2000-12-29 2002-07-03 Nicox S.A. Compositions comprising cyclodextrins and NO- releasing drugs
US7211561B2 (en) 2001-10-12 2007-05-01 Cedars-Sinai Medical Center Method for inducing selective cell death of malignant cells by activation of calcium-activated potassium channels (KCa)
DE60302454T2 (de) 2002-04-19 2006-08-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-agonisten-verbindungen mit stickoxid-donatoren-gruppen und reaktionsfähige sauerstoffspezies-fängergruppen und ihre verwendung bei der behandlung von atemwegsstörungen
WO2003103602A2 (en) 2002-06-11 2003-12-18 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
WO2004002420A2 (en) 2002-06-28 2004-01-08 Nitromed, Inc. Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxigenase-2 selective inhibitors, compositions and methods of use
EP1539729A4 (en) 2002-07-03 2008-02-20 Nitromed Inc NITROSED NON-TESTED OXIDE COMPOUNDS, COMPOSITIONS, AND APPLICATION METHODS
WO2004010945A2 (en) 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase- 2 selective inhibitors, compositions and methods of use
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
AU2005206227A1 (en) * 2004-01-27 2005-08-04 Merck Frosst Company Combination therapy for treating cyclooxygenase-2 mediated diseases or conditions in patients at risk of thrombotic cardiovascular events
ES2338022T3 (es) * 2004-06-10 2010-05-03 Nippon Kayaku Kabushiki Kaisha Potenciador del efecto antineoplasico.
JP2007325501A (ja) * 2004-08-25 2007-12-20 Tottori Univ 非ステロイド性抗炎症薬による動物の消化管副作用の予防・治療方法
JP5274248B2 (ja) 2005-05-27 2013-08-28 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 酸化窒素治療及び医生物的応用のための酸化窒素放出粒子
US20100240745A1 (en) * 2009-03-20 2010-09-23 Nicox S.A. Method of treatment of inflammation in hypertensive patients
CN102695528B (zh) 2009-08-21 2016-07-13 诺万公司 创伤敷料、其使用方法及其形成方法
CA3062005C (en) 2009-08-21 2022-02-15 Novan, Inc. Topical gels comprising nitric oxide-releasing polysiloxane macromolecules and uses thereof
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
EP2681286B1 (en) 2011-02-28 2018-08-15 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
JO3350B1 (ar) 2011-03-07 2019-03-13 Merck Sharp & Dohme مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات
RU2539630C1 (ru) * 2013-07-09 2015-01-20 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ профилактики ишемии сетчатки в эксперименте

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5570683A (en) 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
DK0722434T3 (da) 1993-10-06 1998-11-16 Nicox Sa Salpetersyreestere, der har anti-inflammatorisk og/eller analgetisk aktivitet og fremgangsmåder til deres fremstilling
ES2139199T3 (es) 1994-05-10 2000-02-01 Nicox Sa Compuestos nitro y composiciones que los contienen que presentan una actividad anti-inflamatoria, analgesica y antitrombotica.
US5597809A (en) * 1994-06-23 1997-01-28 Massachusetts Eye & Ear Infirmary Treatment of optic neuritis
US5703073A (en) 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5620416A (en) 1995-06-07 1997-04-15 North Carolina State University Methods of using topical agents with systemically administered active agents

Also Published As

Publication number Publication date
ITMI960352A1 (it) 1997-08-26
US7087588B2 (en) 2006-08-08
CA2247848A1 (en) 1997-09-04
WO1997031654A1 (en) 1997-09-04
EP1221326A3 (en) 2004-01-14
ES2180938T3 (es) 2003-02-16
AU706591B2 (en) 1999-06-17
RU2192247C2 (ru) 2002-11-10
EP0904110A1 (en) 1999-03-31
BR9707739A (pt) 1999-07-27
EP0904110B1 (en) 2002-07-24
EP1221326A2 (en) 2002-07-10
HUP9900993A2 (hu) 1999-09-28
IT1282686B1 (it) 1998-03-31
DE69714253D1 (de) 2002-08-29
KR19990087113A (ko) 1999-12-15
AU2092497A (en) 1997-09-16
US20040242651A1 (en) 2004-12-02
JP2000506133A (ja) 2000-05-23
ITMI960352A0 (esLanguage) 1996-02-26
HUP9900993A3 (en) 2000-10-30
ATE220920T1 (de) 2002-08-15
DE69714253T2 (de) 2003-03-06
CA2247848C (en) 2008-07-15
PT904110E (pt) 2002-12-31

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