DK0863797T3 - Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek - Google Patents

Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek

Info

Publication number
DK0863797T3
DK0863797T3 DK96935090T DK96935090T DK0863797T3 DK 0863797 T3 DK0863797 T3 DK 0863797T3 DK 96935090 T DK96935090 T DK 96935090T DK 96935090 T DK96935090 T DK 96935090T DK 0863797 T3 DK0863797 T3 DK 0863797T3
Authority
DK
Denmark
Prior art keywords
preparation
coded particles
connection library
sequence tracing
combinatorial connection
Prior art date
Application number
DK96935090T
Other languages
Danish (da)
English (en)
Inventor
Paul Henry Kaye
Mark Christopher Tracey
Original Assignee
Univ Hertfordshire
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10782942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0863797(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Hertfordshire filed Critical Univ Hertfordshire
Application granted granted Critical
Publication of DK0863797T3 publication Critical patent/DK0863797T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00502Particles of irregular geometry
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547Bar codes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547Bar codes
    • B01J2219/005492-dimensional
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554Physical means
    • B01J2219/00556Perforations
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554Physical means
    • B01J2219/00558Cuts-out
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554Physical means
    • B01J2219/0056Raised or sunken areas
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00592Split-and-pool, mix-and-divide processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Powder Metallurgy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
DK96935090T 1995-10-26 1996-10-25 Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek DK0863797T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9521943.2A GB9521943D0 (en) 1995-10-26 1995-10-26 Coded particles for process sequence tracking in combinatorial compound library preparation
PCT/GB1996/002617 WO1997015390A1 (en) 1995-10-26 1996-10-25 Coded particles for process sequence tracking in combinatorial compound library preparation

Publications (1)

Publication Number Publication Date
DK0863797T3 true DK0863797T3 (da) 2002-04-15

Family

ID=10782942

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96935090T DK0863797T3 (da) 1995-10-26 1996-10-25 Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek

Country Status (11)

Country Link
EP (2) EP1018365A3 (enExample)
JP (1) JP2000516195A (enExample)
AT (1) ATE210496T1 (enExample)
AU (1) AU696505B2 (enExample)
CA (1) CA2235837A1 (enExample)
DE (1) DE69618001T2 (enExample)
DK (1) DK0863797T3 (enExample)
ES (1) ES2170276T3 (enExample)
GB (2) GB9521943D0 (enExample)
PT (1) PT863797E (enExample)
WO (1) WO1997015390A1 (enExample)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US6025129A (en) 1995-04-25 2000-02-15 Irori Remotely programmable matrices with memories and uses thereof
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US5741462A (en) 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
ATE254965T1 (de) 1995-04-25 2003-12-15 Discovery Partners Internation Fernprogrammierbare matrizen mit speichern und verwendungen davon
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6352854B1 (en) 1995-04-25 2002-03-05 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
GB2326152B (en) * 1996-03-07 2000-06-28 Imperial College A composite for combinatorial organic synthesis
GB9707742D0 (en) * 1997-04-17 1997-06-04 Zeneca Ltd Methods
GB2337269B (en) * 1997-04-17 2002-10-09 Zeneca Ltd Method for the preparation of a chemical library
GB9707741D0 (en) * 1997-04-17 1997-06-04 Zeneca Ltd Process
US6096496A (en) * 1997-06-19 2000-08-01 Frankel; Robert D. Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
AU8376998A (en) * 1997-07-24 1999-02-16 Argonaut Technologies, Inc. Compositions for the storage and delivery of solid phase reactive particles and methods of using the same
US6960457B1 (en) * 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
GB2334347B (en) * 1998-02-13 2001-02-28 Univ Hertfordshire An improved method of fabricating coded particles
AU2534899A (en) * 1998-02-13 1999-08-30 University Of Hertfordshire An improved method of fabricating coded particles
GB9814259D0 (en) * 1998-07-02 1998-09-02 Univ Hertfordshire Improvements to the fabrication and method of use of coded particles in the field of combinatorial chemistry
WO1999047254A1 (en) * 1998-03-13 1999-09-23 Central Research Laboratories Limited Apparatus for, and method of, manufacturing a plurality of uniquely labelled articles
GB9808783D0 (en) * 1998-04-25 1998-06-24 Central Research Lab Ltd Labelling of small articles
WO1999067641A2 (en) 1998-06-24 1999-12-29 Illumina, Inc. Decoding of array sensors with microspheres
GB9820163D0 (en) * 1998-09-17 1998-11-11 Sentec Ltd Micro-fabricated coded labels, reading systems and their applications
CZ20013647A3 (cs) * 1999-04-09 2002-04-17 Glaxo Group Limited Chemická knihovna
US6908737B2 (en) 1999-04-15 2005-06-21 Vitra Bioscience, Inc. Systems and methods of conducting multiplexed experiments
US7253435B2 (en) 1999-04-15 2007-08-07 Millipore Corporation Particles with light-polarizing codes
CA2366093A1 (en) * 1999-04-15 2000-10-26 Ilya Ravkin Combinatorial chemical library supports having indicia at coding positions and methods of use
EP1173760B1 (en) 1999-04-16 2005-06-29 Tibotec BVBA Encoding of microcarriers
US6919009B2 (en) 1999-10-01 2005-07-19 Nanoplex Technologies, Inc. Method of manufacture of colloidal rod particles as nanobarcodes
US7225082B1 (en) 1999-10-01 2007-05-29 Oxonica, Inc. Colloidal rod particles as nanobar codes
US7045049B1 (en) 1999-10-01 2006-05-16 Nanoplex Technologies, Inc. Method of manufacture of colloidal rod particles as nanobar codes
RU2002130821A (ru) * 2000-04-19 2004-04-10 3Д Молекьюлар Сайенсиз Лимитед (Gb) Способ изготовления кодированных частиц
JP2004537712A (ja) 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
US7015047B2 (en) 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
US7811768B2 (en) 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
GB0109545D0 (en) * 2001-04-18 2001-06-06 Scient Generics Ltd Chemical libraries based on coded particles
GB0109746D0 (en) * 2001-04-18 2001-06-13 Scient Generics Ltd Chemical libraries based on coded particles
US7572642B2 (en) 2001-04-18 2009-08-11 Ambrigen, Llc Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns
GB0111470D0 (en) * 2001-05-10 2001-07-04 Scient Generics Ltd Homogenous photoresist functionalisation
WO2003038558A2 (en) * 2001-10-30 2003-05-08 Nanomics Biosystems Pty, Ltd. Device and methods for directed synthesis of chemical libraries
AU2003237213B2 (en) * 2002-06-21 2008-06-05 Stephen D. Nightingale Multi-functional product markers and methods for making and using the same
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US20040058457A1 (en) * 2002-08-29 2004-03-25 Xueying Huang Functionalized nanoparticles
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
CA2499046A1 (en) 2002-09-12 2004-03-25 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
WO2004024328A1 (en) 2002-09-12 2004-03-25 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
JP4520857B2 (ja) 2002-09-20 2010-08-11 インテル・コーポレーション 走査型プローブ顕微鏡検査(spm)読取用の特定の情報をエンコードするナノバーコードの制御された整列
US7361821B2 (en) 2002-09-20 2008-04-22 Intel Corporation Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
CA2539890A1 (en) * 2002-09-27 2004-04-08 Carlsberg A/S Spatially encoded polymer matrix
GB2393784B (en) * 2002-10-03 2005-06-15 Toshiba Res Europ Ltd An identification tag and method of making an identification tag
GB2393785B (en) 2002-10-03 2005-08-31 Toshiba Res Europ Ltd Method of making a free standing structure
US7312257B2 (en) 2003-01-23 2007-12-25 General Electric Company Polymer encapsulation of high aspect ratio materials and methods of making same
GB2405013B (en) * 2003-08-11 2006-02-15 Toshiba Res Europ Ltd A security marker and security marking method
US7488451B2 (en) 2003-09-15 2009-02-10 Millipore Corporation Systems for particle manipulation
WO2005061094A1 (en) 2003-12-22 2005-07-07 Versamatrix A/S Identification of encoded beads
EP1699553A2 (en) 2003-12-22 2006-09-13 VersaMatrix A/S Apparatus and methods for analysis and sorting of particles such as polymer beads
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US20050277710A1 (en) * 2004-06-14 2005-12-15 Joyce Richard P Tagged resin, method of making a tagged resin, and articles made therefrom
WO2006020363A2 (en) 2004-07-21 2006-02-23 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
WO2006055735A2 (en) 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
US7604173B2 (en) 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
DE602005019791D1 (de) 2004-11-16 2010-04-15 Illumina Inc Verfahren und vorrichtung zum lesen von kodierten mikrokugeln
WO2006061600A1 (en) * 2004-12-07 2006-06-15 University Of Southampton Particles for use as a solid support and process for their preparation
GB2422686A (en) * 2004-12-07 2006-08-02 Univ Southampton Preparation of solid support particles for chemical reactions
US8178278B2 (en) 2005-09-13 2012-05-15 Affymetrix, Inc. Miniaturized microparticles
US8592136B2 (en) 2005-09-13 2013-11-26 Affymetrix, Inc. Methods for producing codes for microparticles
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
EP1976626A2 (en) 2006-01-11 2008-10-08 Novo Nordisk A/S Improved spherical encoded beads
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
EP1995329B1 (en) 2007-05-10 2013-09-25 Sony Corporation Method for sequencing nucleic acids
JP4803125B2 (ja) * 2007-05-10 2011-10-26 ソニー株式会社 ビーズ群と該ビーズ群の作製方法、並びにビーズ群を用いる方法
JP4973993B2 (ja) * 2007-07-23 2012-07-11 財団法人生産技術研究奨励会 マイクロビーズの配列装置における解放装置及びその解放装置の設定方法
GB0725306D0 (en) * 2007-12-28 2008-02-06 Pronostics Ltd Improved microparticles
JP2009174954A (ja) * 2008-01-23 2009-08-06 Fujitsu Ltd コード化粒子
JP4582224B2 (ja) * 2008-05-02 2010-11-17 ソニー株式会社 マイクロビーズ作製方法及びマイクロビーズ
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
EP2312393A1 (en) * 2009-10-14 2011-04-20 Biocartis SA Method for producing microparticles
CA2831136A1 (en) 2011-03-21 2012-09-27 Biodesy, Llc Classification of kinase inhibitors using nonlinear optical techniques
US9139863B2 (en) 2012-03-16 2015-09-22 Genentech, Inc. Engineered conformationally-stabilized proteins
HK1205524A1 (en) 2012-03-16 2015-12-18 F. Hoffmann-La Roche Ag Engineered conformationally-stabilized proteins
CN106290917B (zh) 2012-04-25 2020-06-05 比奥德赛公司 用于检测蛋白质的变构调节剂的方法
US10436778B2 (en) 2013-03-15 2019-10-08 Plexbio Co., Ltd. Methods and systems for multiplex assays
US9795121B2 (en) 2014-05-05 2017-10-24 Regeneron Pharmaceuticals, Inc. Humanized C3 animals
EP3237906B8 (en) 2014-12-23 2020-10-28 Bluelight Therapeutics, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
TWI737614B (zh) 2015-06-11 2021-09-01 博錸生技股份有限公司 已編碼微載體及其製造方法以及用以進行多工分析之包含該等已編碼微載體之套件
JP7304697B2 (ja) 2015-12-23 2023-07-07 ムーンショット ファーマ エルエルシー 未成熟終止コドンのリードスルーを促進することにより免疫反応を誘発するための方法
US11796535B2 (en) 2016-09-16 2023-10-24 Plexbio Co., Ltd. Methods and systems for multiplex assays
MX2019010219A (es) 2017-02-27 2020-02-07 Regeneron Pharma Modelo humanizado de trastornos renales y hepáticos.
WO2018237326A1 (en) 2017-06-22 2018-12-27 1AlMOONSHOT PHARMA LLC Methods for treating cancer with compositions comprising amlexanox and immune modulators
JP7252354B2 (ja) * 2019-01-23 2023-04-04 ビージーアイ シェンチェン マイクロビーズ

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053433A (en) * 1975-02-19 1977-10-11 Minnesota Mining And Manufacturing Company Method of tagging with color-coded microparticles
CA1056653A (en) * 1975-11-10 1979-06-19 Edward J. Stevens Color-coded identifier microparticles
US4390452A (en) * 1979-08-20 1983-06-28 Minnesota Mining & Manufacturing Company Microparticles with visual identifying means
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4767205A (en) * 1986-01-28 1988-08-30 Flow Cytometry Standards Corporation Composition and method for hidden identification
CA2118806A1 (en) * 1991-09-18 1993-04-01 William J. Dower Method of synthesizing diverse collections of oligomers
HUT73150A (en) * 1992-11-06 1996-06-28 Chiron Mimotopes Pty Ltd Modular polymer and support for the synthesis thereof
US5429392A (en) * 1993-06-18 1995-07-04 Loving; Charles D. Composite microdot and method
GB2318666B (en) * 1994-04-25 1998-07-15 Univ Hertfordshire Coded items for labelling objects

Also Published As

Publication number Publication date
EP0863797A1 (en) 1998-09-16
EP0863797B1 (en) 2001-12-12
GB9622249D0 (en) 1996-12-18
GB9521943D0 (en) 1996-01-03
DE69618001D1 (de) 2002-01-24
ATE210496T1 (de) 2001-12-15
EP1018365A2 (en) 2000-07-12
EP1018365A8 (en) 2001-03-28
WO1997015390A1 (en) 1997-05-01
DE69618001T2 (de) 2002-08-14
AU7318496A (en) 1997-05-15
EP1018365A3 (en) 2000-10-11
AU696505B2 (en) 1998-09-10
EP1018365A9 (en) 2001-05-16
PT863797E (pt) 2002-05-31
ES2170276T3 (es) 2002-08-01
GB2306484A (en) 1997-05-07
CA2235837A1 (en) 1997-05-01
JP2000516195A (ja) 2000-12-05
GB2306484B (en) 1997-09-24

Similar Documents

Publication Publication Date Title
DK0863797T3 (da) Kodede partikler til sekvenssporing af fremgangsmåde ved fremstilling af kombinatorisk forbindelsesbibliotek
FI943566A7 (fi) Menetelmä kemikaalien tunnistamiseksi käyttäen ei-radioaktiivisia isot ooppeja
EP0415298A3 (en) Method for the determination of hdl-cholesterol using analytical element with integrated fractionation
DE69021309D1 (de) Magnetische Teilchen verwendender Immunotest.
DE69533294D1 (de) Pulverformulierungen, die Melezitose als Verdünnungsmittel enthalten
FR2720356B1 (fr) Procédé pour déterminer la sensibilité de déclenchement d'une opération de freinage automatique.
DE69019198D1 (de) Gerät zur Erzeugung eines Strahls aus geladenen Partikeln.
DE69020424D1 (de) Bildkodierverfahren.
ATE146607T1 (de) Organisches pigment enthaltender farbtoner und verfahren zu dessen herstellung
DK660789A (da) Fremgangsmaade til fremstilling af tonerpartikler til elektrostatiske, flydende fremkaldere
EP0459655A3 (en) Photoresist process employing an i-line peak light source
DE69322815D1 (de) Hierarchische Vorrichtung zur Kodierung/Dekodierung
NO901166D0 (no) Kjoeretoey for avfall.
DE69015549D1 (de) Dispersion von feinen Teilchen eines Kunststoffes.
DE69512354D1 (de) Verfahren zur optischen Projektionsbelichtung
FR2720209B1 (fr) Procédé de réalisation d'une transaction électronique sécurisée.
DE69523248D1 (de) Vorrichtung zur Kodierung/Dekodierung von Bildinformation
FR2711010B1 (fr) Procédé d'incinération de nuclides d'actinides mineurs.
FR2700882B1 (fr) Procédé et installation de décontamination d'une surface radioactive au moyen d'un faisceau de lumière cohérente.
FR2714464B1 (fr) Procédé de contrôle de la contamination surfacique d'un solide et dispositif de mise en Óoeuvre.
FR2704320B1 (fr) Procédé pour la vérification d'un étage terminal.
FR2720853B1 (fr) Procédé de régénération d'un solvant organique dégradé, utilisé pour le retraitement de combustibles nucléaires usés.
FR2708969B1 (fr) Procédé de réalisation d'ouvrages de génie civil et ouvrage obtenu.
FI902744A7 (fi) Säteilyn avulla kovettuva koostumus, joka perustuu polyorganosiloksaaniin joka sisältää propaanialdehydifunktion
FR2651588B1 (fr) Porte-objectif pourvu d'un volet d'occultation pour appareil de projection et appareil de projection comportant un tel porte-objectif.